Teresa Maria Caldeira Martins
|
|
Data da última actualização
»Last update
:
06/04/2011 |
Dados pessoais (Personal data)
Nome completo
Full name |
Teresa Maria Caldeira Martins |
Nome em citações bibliográficas
Quoting name |
Martins, Teresa Maria Caldeira |
Categoria profissional
Position |
Investigador Auxiliar |
Domínio científico de actuação
Scientific domain |
Ciências Naturais-Ciências Biológicas. Ciências Médicas-Ciências da Saúde.
|
Endereço profissional
Professional address |
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra Av. Bissaya Barreto, 98 Coimbra 3000-075 Coimbra Portugal Apartado: 2005 Telefone: (+351)239400200Extensão: 2753 Fax: (+351)239484317 Correio electrónico: tmartins@ipocoimbra.min-saude.pt Homepage: www.ipocoimbra.min-saude.pt |
Sexo
Gender |
Feminino»Female |
Graus Académicos
(Academic Degrees)
1994-1998 |
Doutoramento Phd |
Biomedicina (Imunologia).
Universidade do Porto,
Portugal.
|
1989-1993 |
Licenciatura Licentiate degree |
Biologia
(4 anos » years)
.
Universidade de Coimbra,
Portugal.
|
Formação complementar ( studies)
2008-2008 |
Curso de curta duração Short course |
Neuroimmunology.
Universidade de Coimbra,
Portugal.
|
2008-2008 |
Curso de curta duração Short course |
Oncobiology.
Universidade de Coimbra,
Portugal.
|
2008-2008 |
Curso de curta duração Short course |
Immunology.
Universidade de Coimbra,
Portugal.
|
2008-2008 |
Curso de curta duração Short course |
Cell Death.
Universidade de Coimbra,
Portugal.
|
2007-2007 |
Outros Others |
Workshop European Tissuebanking for Medical Research. Erasmus MC - Roterdam,
Países Baixos.
|
1999-2003 |
Pós-Doutoramento Postdoctorate |
Universidade do Porto,
Portugal.
|
2000-2000 |
Outros Others |
1st International Symposium on Laboratory Animals. Universidade de Coimbra,
Portugal.
|
1999-1999 |
Curso de curta duração Short course |
V Curso de Genética em Oncologia.
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra,
Portugal.
|
1997-1997 |
Curso de curta duração Short course |
Modulation of the Immune system.
Universidade do Porto,
Portugal.
|
1996-1996 |
Curso de curta duração Short course |
Activation of the Immune System.
Universidade do Porto,
Portugal.
|
1995 |
Curso de curta duração Short course |
Immune system: genes and development.
Sociedade Portuguesa de Imunologia,
Portugal.
|
1995 |
Curso de curta duração Short course |
Basic Immunology.
Fundação Calouste Gulbenkian,
Portugal.
|
1994 |
Curso de curta duração Short course |
Immunity to Intracellular Infections.
Universidade do Porto,
Portugal.
|
1993 |
Curso de curta duração Short course |
II Curso de Genética em Oncologia.
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra,
Portugal.
|
1992 |
Curso de curta duração Short course |
Curso Teórico-Prático de Psiquiatria Genética.
Hospitais da Universidade de Coimbra,
Portugal.
|
1992 |
Curso de curta duração Short course |
I Curso de Genética em Oncologia.
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra,
Portugal.
|
Vínculos profissionais
(Professional Positions)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Mai/2003-Actual |
Investigador Auxiliar |
Escola Universitária Vasco da Gama |
Set/2002-Set/2005 |
Professor Auxiliar |
Jan/1994-Mai/2003 |
Outra Situação |
Escola Superior de Enfermagem Cidade do Porto |
Out/1999-Dez/1999 |
Professor Auxiliar |
Actividades de Investigação e Desenvolvimento (Research and Development activities)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Actividades de Ensino (Teaching activities)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Actividades de Conselhos, Comissões e Consultorias (Councils, Comissions and Consultancy activities)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Out/2007-Actual |
|
Vogal do Gabinete Coordenador da Investigação |
Actividades de Direcção e Administração (Management and Administration activities)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Fev/2004-Actual |
|
-
Directora do Laboratório de Patologia Molecular |
Actividades de Extensão Universitária (Other services rendered through University)
Instituto Português de Oncologia Doutor Francisco Gentil - IPO Coimbra |
Ago/2004-Actual |
|
Actividade de extensão realizada»Extension activity rendered: - Ocupação Temporária de Jovens nas Férias - Ciência Viva |
Linhas de Investigação (Research fields)
1. |
Genética e Biologia do cancro |
|
|
Projectos de Investigação (Research projects)
Outro Tipo de Participação Other kind of participation |
Experimental autoimmune diabetes vaccination: role of Treg cells and pro-inflammatory cytokines |
Referência do projecto»Project reference: POCTI/MGI/34175/99.
|
Lymphocyte antigen CD38 and immune homeostasis |
Referência do projecto»Project reference: POCTI/BCI/34197/99.
|
Multifunctional ectoenzymes CD38 e CD157: role in solid tumours and lymphoid malignancies |
Referência do projecto»Project reference: POCTI/BCI/44109/2002.
|
Risk-modifying genetic factors in BRCA172-associated breast and/or ovarian cancer |
Referência do projecto»Project reference: POCTI/MGI/48912/2002.
|
Analysis of molecular alterations that are relevant for GIST carcinogenesis and treatment |
Referência do projecto»Project reference: Novartis Oncology.
|
Línguas (Languages)
Compreende Understandig |
Inglês (Bem), Espanhol (Bem), Francês (Razoavelmente). |
Fala Speaking |
Inglês (Bem), Espanhol (Bem), Francês (Razoavelmente). |
Lê Reading |
Inglês (Bem), Espanhol (Bem), Francês (Razoavelmente). |
Escreve Writing |
Inglês (Bem), Espanhol (Bem), Francês (Razoavelmente). |
Prémios e títulos (Awards Prizes, and Honours)
1998 |
1º Prémio Bial em Biomedicina,
Bial.
|
2007 |
Bolsa Prof. E Limbert em Patologia da Tiróide,
Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo /Genzyme.
|
Membro de Associações Profissionais/Científicas (Professional/Scientific Association membership)
2007- Actual |
European Association for Cancer Research, Membro.
|
Nov/1994 - Actual |
Portuguese Immunology Society (SPI), Membro.
|
Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Capítulos de livros publicados Published book chapters |
1. |
Martins, Teresa C. 2009. Mycobacteria and autoimmunity: the two sides of a coin. In Cur. Topics on the Profiles of Host Immunological Response to Mycobacterial Infections, 183 - 217. . India: Research Signpost. |
|
|
|
Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing |
1. |
Prazeres, Hugo J; Torres, Joana; Rodrigues, Fernando; Vinagre, João; Teixeira, Marta; Pastoriza, M C; Gomes, Daniela; Cameselle-Teijeiro, José; Vidal, Anxo; Martins, Teresa C; Simões, Manuel S; Soares, Paula. 2011. "Multiple levels of inactivation of LRP1B, a modulator of MMP2 in the extracellular environment of human cancer cells", Oncogene 30, 11: 1302 - 1317. |
|
|
|
2. |
Nobre, Rui J; Cruz, Eugénia; Real, Odete; Almeida, Luís P; Martins, Teresa C. 2010. "Characterization of the Common and Rare Human Papillomaviruses in Portuguese Women by Polymerase Chain Reaction, Restriction
Fragment Length Polymorphism and Sequencing", J. Med. Virol, 82: 1024 - 1032. |
|
|
|
3. |
Prazeres, Hugo J; Rodrigues, Fernando; Naidenov, Plamen; Figueiredo, Paulo; Soares, Paula; Lacerda, Manuela; Campos, Beatriz; Martins, Teresa C. 2008. "Loss of Heterozygosity at 19p13.2 and 2q21 in Tumours from Familial Clusters of Non-Medullary Thyroid Carcinoma", Familial Cancer , 7: 141 - 149. |
|
|
|
4. |
Nobre, Rui J; Almeida, Luís P; Martins, Teresa C. 2008. "Complete genotyping of mucosal human papillomavirus using a restriction fragment length polymorphism analysis and an original
typing algorithm", J. Clin. Virol, 42: 13 - 21. |
|
|
|
5. |
Viegas, Marta S; Seco, F; Martins, Teresa C; Carmo, Anália. 2007. "An improved and cost effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed
paraffin-embedded tissues", Eur. J. Histochemistry , 51: 59 - 66. |
|
|
|
6. |
Viegas, Marta S; Carmo, Anália; Seco, F; Lacerda, Manuela; Martins, Teresa C. 2007. "CD38 plays a role in effective containment of mycobacteria within granulomata and polarization of Th1 immune responses against
Mycobacterium avium", Microbes Infect, 9: 847 - 854. |
|
|
|
7. |
Martins, Teresa C; Prazeres, Hugo J; Rodrigues, Fernando; Figueiredo, Paulo; Naidenov, Plamen; Soares, Paula; Bugalho, Maria J; Faro, Carlos; Campos, Beatriz; Lacerda, Manuela. 2006. "Recurrence of the Cys611Tyr mutation and a novel Arg886Trp substitution in the RET proto-oncogene in multiple endocrine neoplasia
type 2 families and sporadic medullary thyroid carcinoma cases originating from the central region of Portugal", Clin. Endocrinol 64, -: 659 - 666. |
|
|
|
8. |
Martins, Teresa C. 2005. "Buba – adapting to a life on three legs", FAB Journal 43, -: 56 - 57. |
|
|
|
9. |
Martins, Teresa C; Águas, Artur P. 1999. "Mechanisms of M. avium-induced resistance against IDDM in non-obese diabetic (NOD) mice: role of Fas and Th1 cells", Clin. Exp. Immunol 115, -: 248 - 254. |
|
|
|
10. |
Martins, Teresa C; Águas, Artur P. 1999. "NOD mice are resistant to depletion of thymic cells caused by acute stress or infection", Autoimmunity 29, -: 273 - 280. |
|
|
|
11. |
Martins, Teresa C; Águas, Artur P. 1999. "A role for CD45RBloCD38 T cells and co-stimulatory pathways of T cell activation in protection of NOD mice from diabetes", Immunology 96, -: 600 - 605. |
|
|
|
12. |
Martins, Teresa C; Águas, Artur P. 1998. "Involvement of c-myc in the resistance of non-obese diabetic (NOD) to glucocorticoid-induced apoptosis", Immunology 95, 3: 377 - 382. |
|
|
|
13. |
Martins, Teresa C; Águas, Artur P. 1996. "Changes in B and T lymphocytes associated with mycobacteria-induced protection of NOD mice from diabetes", J. Autoimmunity 9, -: 501 - 507. |
|
|
|
14. |
Martins, Teresa C; Águas, Artur P. 1995. "Stress modulates acute inflammation triggered by mycobacteria in autoimmunity-prone and normal mice", Inflamm. Res. 44, -: 393 - 399. |
|
|
|
Trabalhos completos/resumidos em eventos com arbitragem científica Papers in conference proceedings with scientific refereeing |
1. |
Martins, Teresa C; Viegas, Marta S; Lund, Frances; Thankappan, A. 2010. "CD38 is required for dendritic cell priming of Th1 responses to Mycobacterium avium infection", Trabalho apresentado em 14th International Congress of Immunology., In International Immunol , Kobe. |
|
|
|
2. |
Martins, Teresa C; Viegas, Marta S. 2009. "Absence of CD38 compromises leukocyte recruitment and macrophage activation during responses to mycobacteria", Trabalho apresentado em III International Congress of Molecular Medicine, In IUBMB Life, Istanbul. |
|
|
|
3. |
Martins, Teresa C; Gonçalves, Vera; Pais, Rosete. 2009. "Polymorphisms in DEFA1, 2 and 3 and DEFA5 are associated with increased risk for HPV infection and development of cervical
cancer.", Trabalho apresentado em III International Congress of Molecular Medicine, In IUBMB Life , Istanbul. |
|
|
|
4. |
Gonçalves, Vera; Prazeres, Hugo J; Lacerda, Manuela; Martins, Teresa C. 2009. "Genetic susceptibility factors for breast cancer in the Portuguese population: AIB1, PPARGC1A, CYP1A1 and DSS1", Trabalho apresentado em III International Congress of Molecular Medicine, In IUBMB Life , Istanbul. |
|
|
|
5. |
Martins, Teresa C; Gonçalves, Vera; Pais, Rosete; Teles, Vera. 2009. "Polymorphisms in DEFA1, 2, 3, DEFA5 and TLR7: association with susceptibility to HPV infection and persistence and development
of cervical cancer", Trabalho apresentado em 2nd European Congress of Immunology, In Eur. J. Immunol, Berlin. |
|
|
|
6. |
Martins, Teresa C; Viegas, Marta S; Lun, Frances; Cooper, Andrea; Pearl, John. 2009. "CD38 plays a role in the development of productive immune responses against Mycobacterium tuberculosis", Trabalho apresentado em 2nd European Congress of Immunology, In Eur J Immunol, Berlin. |
|
|
|
7. |
Lacerda, Manuela; Gonçalves, Vera; Monteiro, Maria M; Madeira, Andreia; Martins, Teresa C. 2008. "Loss of expression of Claspin in tumour cells may be involved in breast carcinogenesis", Trabalho apresentado em 20th Meeting of the European Association for Cancer Research – EACR20, In European J. Cancer, Lyon, France. |
|
|
|
8. |
Viegas, Marta S; Carmo, Anália; Martins, Teresa C. 2006. "Absence of CD38 accelerates development of a lupus-like disease in C57Bl.6-lpr/lpr mice", Trabalho apresentado em The CD38 ectoenzyme family: advances in basic science and clinical practice, In Molecular Medicine, Turin, Itália. |
|
|
|
9. |
Viegas, Marta S; Martins, Teresa C. 2004. "Absence of CD38 accelerates development of systemic autoimmune disease", Trabalho apresentado em 4th International Congress on Autoimmunity, In Autoimmun. Rev., Budapeste. |
|
|
|
10. |
Ferreira, Patrícia; Martins, Teresa C. 2004. "Prevention of diabetes in NOD mice: role for TGFbeta-CD40 cross-talk on B cells.", Trabalho apresentado em 4th International Congress on Autoimmunity, In Autoimmun. Rev., Budapeste. |
|
|
|
11. |
Rodrigues, Monica I; Águas, Artur P; Martins, Teresa C. 2003. "Deficient activation of NOD T cells: reduced tyrosine phosphorylation and c-myc expression", Trabalho apresentado em 15th European Immunology Meeting, In Immunol. Lett., Rhodes. |
|
|
|
12. |
Viegas, Marta S; Águas, Artur P; Martins, Teresa C. 2003. "CD38: a role in immunity to mycobacterial infection? ", Trabalho apresentado em 15th European Immunology Meeting, In Immunol. Lett, Rhodes. |
|
|
|
13. |
Ferreira, Patrícia; Águas, Artur P; Martins, Teresa C. 2003. "Prevention of autoimmune diabetes of NOD mice by mycobacterial infection: role for myeloid and lymphoid dendritic cells", Trabalho apresentado em 15th European Immunology Meeting, In Immunol. Letts., Rhodes. |
|
|
|
14. |
Martins, Teresa C; Águas, Artur P. 2003. "Vaccination of NOD mice against diabetes by Mycobacterium avium infection: rescue of high activation threshold T cells from
hyporresponsiveness.", Trabalho apresentado em 15th European Immunology Meeting, In Immunol. Letts, Rhodes. |
|
|
|
15. |
Martins, Teresa C; Ferreira, Patrícia; Huygen, Kris; Águas, Artur P. 2003. "DNA vaccination of NOD mice against diabetes: role for IgG B cells and CD28-CD8 T cells?", Trabalho apresentado em 15th European Immunology Meeting, In Immunol. Letts., Rhodes. |
|
|
|
16. |
Martins, Teresa C; Águas, Artur P. 2000. "Diabetes vaccination: role of Treg cells in mycobacteria -induced resistance against diabetes in NOD mice ", Trabalho apresentado em 14th European Immunology Meeting, In Immunol. Lett. , Poznan. |
|
|
|
Apresentação oral de trabalho Oral work presentation |
1. |
Viegas, Marta S; Carmo, Anália; Martins, Teresa C. Absence of CD38 accelerates development of a lupus-like disease in C57Bl.6-lpr/lpr mice.,The CD38 ectoenzyme family: advances in basic science and clinical practice.,Turin,2006 (Comunicação). |
2. |
Prazeres, Hugo J; Gonçalves, Vera; Viegas, Marta S; Leite, Ana M; Santos, AH; Lima, Margarida; Martins, Teresa C. Lymphocyte differentiation marker CD38 and immune homeostasis: PvuII polymorphisms and development of B-chronic lymphocytic
leukaemia,2nd ESF – Functional Genomics Conference,Oslo,2005 (Poster). |
3. |
Viegas, Marta S; Martins, Teresa C. Relevance of CD38 on immune homeostasis: knocking out of CD38 accelerates development of autoimmune disease with kidney involvement,2nd ESF – Functional Genomics Conference,Oslo,2005 (Poster). |
4. |
Prazeres, Hugo J; Martins, Teresa C. Whole genomic allelic imbalance analysis in familial non-medullary thyroid cancer. ,2nd ESF – Functional Genomics Conference,Oslo,2005 (Poster). |
5. |
Martins, Teresa C; Prazeres, Hugo J; Cruz, Eugénia. CD157 polymorphisms on exon 3 are associated with development of cervical cancer in HPV-infected women,21st International Conference and Clinical Workshop on Papillomavirus,Cidade do México,2004 (Poster). |
6. |
Prazeres, Hugo J; Leite, Ana M; Martins, Teresa C. CD38 PvuII polymorphisms: over-representation of the AA genotype in B-CLL patients,XII Meeting of the European Association for Haematopathology.,Saloniki,2004 (Poster). |
7. |
Viegas, Marta S; Martins, Teresa C. Absence of CD38 accelerates development of systemic autoimmune disease. ,4th International Congress on Autoimmunity,Budapest,2004 (Poster). |
8. |
Ferreira, Patrícia; Martins, Teresa C. Prevention of diabetes in NOD mice: role for TGFbeta-CD40 cross-talk on B cells,4th International Congress on Autoimmunity,Budapest,2004 (Poster). |
9. |
Rodrigues, Mónica I; Águas, Artur P; Martins, Teresa C. Deficient activation of NOD T cells: reduced tyrosine phosphorylation and c-myc expression,15th European Immunology Meeting,Rhodes,2003 (Poster). |
10. |
Viegas, Marta S; Águas, Artur P; Martins, Teresa C. CD38: a role in immunity to mycobacterial infection? ,15th International Immunology Congress,Rhodes,2003 (Poster). |
11. |
Ferreira, Patrícia; Águas, Artur P; Martins, Teresa C. Prevention of autoimmune diabetes of NOD mice by mycobacterial infection: role for myeloid and lymphoid dendritic cells,15th European Immunology Meeting,Rhodes,2003 (Poster). |
12. |
Martins, Teresa C; Águas, Artur P. Vaccination of NOD mice against diabetes by Mycobacterium avium infection: rescue of high activation threshold T cells from
hyporresponsiveness,15th European Immunology Meeting,Rhodes,2003 (Poster). |
13. |
Martins, Teresa C; Ferreira, Patrícia; Huygen, Kris; Águas, Artur P. DNA vaccination of NOD mice against diabetes: role for IgG B cells and CD28-CD8 T cells?,15th European Immunology Meeting,Rhodes,2003 (Poster). |
14. |
Martins, Teresa C; Águas, Artur P. Effects of TGFbeta on B cells of vaccinated NOD mice are dependent on costimulation via CD40: role for inhibitory Smads?,6th International Symposium on “Predictive Oncology and Intervention Strategies”,Paris,2002 (Poster). |
15. |
Martins, Teresa C; Águas, Artur P. Glucocorticoid resistance of NOD mice lymphocytes: defective suppression of c-myc transcription results from delayed dissociation
of glucocorticoid receptor complex.,3rd International Congress on Signal Transduction,Dubrovnik,2002 (Poster). |
16. |
Viegas, Marta S; Águas, Artur P; Martins, Teresa C. Signalling cascade of CD38 in lupus-prone and normal mice: differences in c-myc expression and protein tyrosine phosphorylation,3rd International Congress on Signal Transduction,Dubrovnik,2002 (Poster). |
17. |
Martins, Teresa C; Águas, Artur P. Regulation by TGFbeta of CD40 expression on B cells of NOD mice vaccinated against diabetes,10th International Congress of Immunology,Stockolm,2001 (Poster). |
18. |
Martins, Teresa C; Águas, Artur P. In vitro response to SA-5K of immune cells from mycobacteria-immunised mice.,3rd BIOMED Meeting,Pisa,2000 (Comunicação). |
19. |
Martins, Teresa C; Águas, Artur P. Diabetes vaccination: role of Treg cells in mycobacteria -induced resistance against diabetes in NOD mice. ,14th European Immunology Meeting,Poznan,2000 (Comunicação). |
20. |
Martins, Teresa C; Águas, Artur P. Immune response to SA-5K,2nd BIOMED Meeting,Pisa,1999 (Comunicação). |
21. |
Martins, Teresa C; Águas, Artur P. Infection and apoptosis in NOD mice.,13th European Immunology Meeting,Amsterdam,1997 (Poster). |
22. |
Martins, Teresa C; Águas, Artur P. Infection and/or stress modify apoptosis frequency and lymphocyte subpopulations in the thymus of mice,14th International Congress: The Phagocyte - molecular and clinical aspects,Verona, Itália,1996 (Poster). |
23. |
Martins, Teresa C; Águas, Artur P. Mycobacteria-induced protection of NOD mice from diabetes is associated with enhancement in CD4+ T cells and B220+ B cells,2nd Symposium on the Pathogenesis and Immunotherapy of Autoimmune Diseases.,Milano,1996 (Poster). |
24. |
Martins, Teresa C; Águas, Artur P. Acute stress changes the inflammatory response of lupus-prone NZB/W mice.,9th International Congress of Immunology,San Francisco,1995 (Poster). |
Organização de evento Event organization |
1. |
Martins, Teresa C; Lopes, Maria C. Oncobiology,2007 (Outro / Organização). |
Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Produção técnica
Technical production |
Produção científica Scientific production |
31 |
Livros e capítulos Books and book chapters |
1 |
Capítulos de livros publicados Published book chapters |
1 |
Artigos científicos em revistas Papers in periodics |
14 |
Com arbitragem científica With scientific refereeing |
14 |
Trabalhos em eventos Papers in conference proceedings |
16 |
Com arbitragem científica With scientific refereeing |
16 |
Produção técnica Technical production |
25 |
Outros tipos de produção técnica Other technical production |
25 |
Visualizações do curriculum [
19
]
|
Página gerada pelo sistema Currículum DeGóis promovido pela FCT e GPEARI do MCTES e pelo Gávea/DSI/UM
em
24-01-2012
às
19:54:51
|
Plataforma de Curricula DeGóis: http://curriculum.degois.pt |
|