Curriculum Vitae

João Alexandre Reis Mendes Moreira
	Data da última atualização »Last update : 01/07/2014

João Alexandre Reis Mendes Moreira Publicou 37 artigos em revistas especializadas. Nas suas actividades profissionais interagiu com 88 colaboradores em co-autorias de trabalhos científicos.

Endereço de acesso a este CV: http://www.degois.pt/visualizador/curriculum.jsp?key=7907927727191275

Dados pessoais (Personal data)

Nome completo Full name	João Alexandre Reis Mendes Moreira
Nome em citações bibliográficas Quoting name	Moreira, João Alexandre Reis Mendes

Sexo
Gender

Masculino»Male

Graus Académicos (Academic Degrees)

Produção científica, técnica e artística/cultural (Scientific, technical and artistical/cultural production)

Artigos em revistas sem arbitragem científica
Papers in periodics without scientific refereeing

1.	Caldeira, M.V.; Curcio, M.; Leal, G.; Salazar, I.L.; Mele, M.; Santos, A.R.A.; Melo, C.V.; Pereira, P.; Canzoniero, L.M.T.; Duarte, C.B.. 2013. "Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons", Biochimica et Biophysica Acta - Molecular Basis of Disease 1832, 1: 263 - 274.

2.	Ferreira, J.V.; Fofo, H.; Bejarano, E.; Bento, C.F.; Ramalho, J.S.; Girao, H.; Pereira, P.. 2013. "STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy", Autophagy 9, 9: 1349 - 13.

3.	Bejarano, E.; Girao, H.; Yuste, A.; Patel, B.; Marques, C.; Spray, D.C.; Pereira, P.; Cuervo, A.M.. 2012. "Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner", Molecular Biology of the Cell 23, 11: 2156 - 21.

4.	Matafome, P.; Santos-Silva, D.; Crisóstomo, J.; Rodrigues, T.; Rodrigues, L.; Sena, C.M.; Pereira, P.; Seiça, R.. 2012. "Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity", Archives of Physiology and Biochemistry 118, 2: 58 - 68.

5.	Sena, C.M.; Matafome, P.; Crisóstomo, J.; Rodrigues, L.; Fernandes, R.; Pereira, P.; Seiça, R.M.. 2012. "Methylglyoxal promotes oxidative stress and endothelial dysfunction", Pharmacological Research 65, 5: 497 - 506.

6.	Bento, C.F.; Pereira, P.. 2011. "Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes", Diabetologia 54, 8: 1946 - 19.

7.	Catarino, S.; Ramalho, J.S.; Marques, C.; Pereira, P.; Girão, H.. 2011. "Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal", Biochemical Journal 437, 2: 255 - 267.

8.	Sena, C.M.; Bento, C.F.; Pereira, P.; Seiça, R.. 2010. "Diabetes mellitus: New challenges and innovative therapies", EPMA Journal 1, 1: 138 - 163.

9.	Bento, C.F.; Fernandes, R.; Matafome, P.; Sena, C.M.; Seia, R.; Pereira, P.. 2010. "Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction", Experimental Physiology 95, 9: 955 - 970.

10.	Fernandes, A.F.; Bian, Q.; Jiang, J.-K.; Thomas, C.J.; Taylor, A.; Pereira, P.; Shang, F.. 2009. "Proteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells", Molecular Biology of the Cell 20, 16: 3690 - 36.

11.	Girão, H.; Catarino, S.; Pereira, P.. 2009. "Eps15 interacts with ubiquitinated Cx43 and mediates its internalization", Experimental Cell Research 315, 20: 3587 - 35.

12.	Wu, M.; Bian, Q.; Liu, Y.; Fernandes, A.F.; Taylor, A.; Pereira, P.; Shang, F.. 2009. "Sustained oxidative stress inhibits NF-¿B activation partially via inactivating the proteasome", Free Radical Biology and Medicine 46, 1: 62 - 69.

13.	Zhang, X.; Zhou, J.; Fernandes, A.F.; Sparrow, J.R.; Pereira, P.; Taylor, A.; Shang, F.. 2008. "The proteasome: A target of oxidative damage in cultured human retina pigment epithelial cells", Investigative Ophthalmology and Visual Science 49, 8: 3622 - 36.

14.	Fernandes, A.F.; Zhou, J.; Zhang, X.; Bian, Q.; Sparrow, J.R.; Taylor, A.; Pereira, P.; Shang, F.. 2008. "Oxidative inactivation of the proteasome in retinal pigment epithelial cells: A potential link between oxidative stress and up-regulation of interleukin-8", Journal of Biological Chemistry 283, 30: 20745 - 20.

15.	Girao, H.; Pereira, P.. 2007. "The proteasome regulates the interaction between Cx43 and ZO-1", Journal of Cellular Biochemistry 102, 3: 719 - 728.

16.	Marques, C.; Guo, W.; Pereira, P.; Taylor, A.; Patterson, C.; Evans, P.C.; Shang, F.. 2006. "The triage of damaged proteins: Degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones", FASEB Journal 20, 6: 741 - 743.

17.	Fernandes, A.F.; Guo, W.; Zhang, X.; Gallagher, M.; Ivan, M.; Taylor, A.; Pereira, P.; Shang, F.. 2006. "Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cells", Experimental Eye Research 83, 6: 1472 - 14.

18.	Girão, H.; Pereira, P.; Taylor, A.; Shang, F.. 2005. "Subcellular redistribution of components of the ubiquitin-proteasome pathway during lens differentiation and maturation", Investigative Ophthalmology and Visual Science 46, 4: 1386 - 13.

19.	Fernandes, R.; Girão, H.; Pereira, P.. 2004. "High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism", Journal of Biological Chemistry 279, 26: 27219 - 27.

20.	Marques, C.; Pereira, P.; Taylor, A.; Liang, J.N.; Reddy, V.N.; Szweda, L.I.; Shang, F.. 2004. "Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells", FASEB Journal 18, 12: 1424 - 14.

21.	Girão, H.; Pereira, P.; Ramalho, J.S.; Quinlan, R.; Prescott, A.. 2003. "Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases", Experimental Cell Research 291, 2: 502 - 513.

22.	Pereira, P.; Shang, F.; Hobbs, M.; Girão, H.; Taylor, A.. 2003. "Lens fibers have a fully functional ubiquitin-proteasome pathway", Experimental Eye Research 76, 5: 623 - 631.

23.	Nourooz-Zadeh, J.; Pereira, P.. 2000. "F2 isoprostanes, potential specific markers of oxidative damage in human retina", Ophthalmic Research 32, 4: 133 - 137.

24.	England, T.; Beatty, E.; Rehman, A.; Nourooz-Zadeh, J.; Pereira, P.; O\'Reilly, J.; Wiseman, H.; Geissler, C.; Halliwell, B.. 2000. "The steady-state levels of oxidative DNA damage and of lipid peroxidation (F2-isoprostanes) are not correlated in healthy human subjects", Free Radical Research 32, 4: 355 - 362.

25.	El-Khoury, A.E.; Pereira, P.C.M.; Borgonha, S.; Basile-Filho, A.; Beaumier, L.; Wang, S.Y.; Metges, C.C.; Ajami, A.M.; Young, V.R.. 2000. "Twenty-four-hour oral tracer studies with L-[1-13C]lysine at a low (15 mg · kg-1 · d-1) and intermediate (29 mg · kg-1 · d-1) lysine intake in healthy adults", American Journal of Clinical Nutrition 72, 1: 122 - 130.

26.	Raguso, C.A.; Pereira, P.; Young, V.R.. 1999. "A tracer investigation of obligatory oxidative amino acid losses in healthy, young adults", American Journal of Clinical Nutrition 70, 4: 474 - 483.

27.	Nourooz-Zadeh, J.; Pereira, P.. 1999. "Age-related accumulation of free polyunsaturated fatty acids in human retina", Ophthalmic Research 31, 4: 273 - 279.

28.	Rehman, A.; Nourooz-Zadeh, J.; Möller, W.; Tritschler, H.; Pereira, P.; Halliwell, B.. 1999. "Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus", FEBS Letters 448, 1: 120 - 122.

29.	Girao, H.; Mota, C.; Pereira, P.. 1999. "Cholesterol may act as an antioxidant in lens membranes", Current Eye Research 18, 6: 448 - 454.

30.	Mota, M.C.; Morgado, A.M.; Matos, A.; Pereira, P.; Burrows, H.. 1999. "Evaluation of a non-invasive fluorescence technique as a marker for diabetic lenses in vivo", Graefe's Archive for Clinical and Experimental Ophthalmology 237, 3: 187 - 192.

31.	Girão, H.; Mota, M.C.; Ramalho, J.S.; Pereira, P.. 1998. "Cholesterol oxides accumulate in human cataracts", Experimental Eye Research 66, 5: 645 - 652.

32.	Fernandes, R.; Pereira, P.; Ramalho, J.S.; Mota, M.C.; Oliveira, C.R.. 1996. "An experimental model for the evaluation of lipid peroxidation in lens membranes", Current Eye Research 15, 4: 395 - 402.

33.	Pereira, P.C.M.; Fernandes, R.; Ramalho, J.S.; Mota, M.C.; Oliveira, C.R.. 1996. "A technical approach to the evaluation of glucose oxidation: Implications for diabetic cataract", Ophthalmic Research 28, 5: 275 - 283.

34.	Yugay, M.T.; Pereira, P.C.M.; Leiria, F.; Mota, M.C.. 1996. "Oxidative damage to lens membranes induced by metal-catalyzed systems", Ophthalmic Research 28, SUPPL. 1: 92 - 96.

35.	Ramalho, J.S.; Marques, C.; Pereira, P.C.M.; Mota, M.C.. 1996. "Role of glycation in human lens protein structure change", European Journal of Ophthalmology 6, 2: 155 - 161.

36.	Marques, C.; Ramalho, J.S.; Pereira, P.; Mota, M.C.. 1995. "Bendazac decreases in vitro glycation of human lens crystallins. Decrease of in vitro protein glycation by bendazac", Documenta Ophthalmologica 90, 4: 395 - 404.

37.	Pereira, P.C.M.; Ramalho, J.S.; Faro, C.J.; Mota, M.C.. 1994. "Age-Related changes in normal and cataractous human lens crystallins, separated by fast-performance liquid chromatography", Ophthalmic Research 26, 3: 149 - 157.

Outra produção científica
Other scientific production

1.	Moreira, João M; Carvalho, José; Saraiva, Ricardo; Rodrigues, Eloy. 2010. "Repositório Científico de Acesso Aberto de Portugal : uma ferramenta ao serviço da ciência portuguesa", 10 pp.. Sem local: Associação Portuguesa de Bibli.