António Gil Pereira de Castro
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                        												Data da última atualização
                        												»Last update
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                        												16/03/2011 | 
                
              
            
 Dados pessoais (Personal data)  
            
               
                  
                     Nome completo
                        						 Full name | 
                     António Gil Pereira de Castro | 
                   
                  
                     Nome em citações bibliográficas
                        							 Quoting name | 
                     Castro, António Gil Pereira de  | 
                   
                  
                     Categoria profissional
                        					 Position | 
                     Professor Associado | 
                   
                
               
                  
                     Endereço profissional
                        						 Professional address | 
                     Universidade do Minho Escola de Ciências da Saúde Instituto de Investigação em Ciências da Vida e da Saúde (ICVS) Campus de Gualtar Gualtar 4710-057 Braga Portugal Telefone: (+351)253604815Extensão: 604815 Correio electrónico: acastro@ecsaude.uminho.pt | 
                   
                
               
                  
                     Sexo
                        							 Gender | 
                     Masculino»Male | 
                   
                 
 
                  			Graus Académicos
                  			 (Academic Degrees) 
            
               
                  
                     | 1990-1994 | 
                     Doutoramento Phd | 
                   
                  
                     Microbiologia
                        							(3 anos » years)
                        						.
                        					 Universidade do Porto,
                        			Portugal.
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                     | 1982-1987 | 
                     Licenciatura Licentiate degree | 
                   
                  
                     Biologia
                        							(4 anos » years)
                        						.
                        					 Universidade do Porto,
                        			Portugal.
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 Formação complementar ( studies) 
            
               
                  
                     | 2005-2008 | 
                     Pós-Doutoramento Postdoctorate | 
                   
                  
                     | 3 anos » years.
                        						DNAX Research Institute,
                        			Estados Unidos.
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                     | 1998-2000 | 
                     Pós-Doutoramento Postdoctorate | 
                   
                  
                     | 2 anos » years.
                        						Fundação Calouste Gulbenkian,
                        			Portugal.
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 Vínculos profissionais
                  				 (Professional Positions) 
            
               
               
                  
                     | Out/2002-Actual | 
                     Professor Associado | 
                   
                
               
               
                  
                     | Out/2001-Set/2002 | 
                     Professor Auxiliar | 
                   
                
               
                  
                     | Cooperativa de Ensino Superior Politécnico e Universitário | 
                   
                
               
                  
                     | Out/2000-Set/2002 | 
                     Professor Auxiliar | 
                   
                 
 Prémios e títulos (Awards Prizes, and Honours) 
            
               
                  
                     | 1994 | 
                     Prémio Pfizer de Investigação,
                        					Pfizer.
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                     | 2006 | 
                     Prémio Citomed R&D, Melhor Poster,
                        					Citomed R&D.
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                     | 2006 | 
                     Prémio de Excelência em Imunologia Mário Arala Chaves,
                        					Sociedade Portuguêsa de Imunologia.
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                     | 2010 | 
                     SPI Best Paper Award, 2010,
                        					Sociedade Portuguêsa de Imunologia.
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                     | 2010 | 
                     Prémio Pulido Valente Ciência 2010,
                        					Fundação Professor Francisco Pulido Valente e Fundação para a Ciência e Tecnologia.
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                  											Produção científica, técnica e artística/cultural
                  											 (Scientific, technical and artistical/cultural
                     													production) 
            
               
                  
                     Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing | 
                   
                
               
                  
                     | 1. | 
                     Nobrega, Claudia; Roque, Susana; Nunes-Alves, Cláudio; Coelho, Angela; Medeiros, Irene; Castro, António G; Appelberg, Rui; Correia-Neves, Margarida.  2010. "Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen", Journal of Immunology {(Baltimore,} Md.: 1950) 184, 1: 351 - 358.
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                     | 2. | 
                     Oliveira, João T; Santos, Tírcia C; Martins, Luís; Picciochi, Ricardo; Marques, Alexandra P; Castro, António G; Neves, Nuno M; Mano, João F; Reis, Rui L.  2010. "Gellan gum injectable hydrogels for cartilage tissue engineering applications: in vitro studies and preliminary in vivo evaluation", Tissue Engineering. Part A 16, 1: 343 - 353.
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                     | 3. | 
                     Torrado, Egídio; Fraga, Alexandra G; Logarinho, Elsa; Martins, Teresa G; Carmona, Jenny A; Gama, José B; Carvalho, Maria A; Proença, Fernanda; Castro, Antonio G; Pedrosa, Jorge.  2010. "{IFN-gamma-dependent} activation of macrophages during experimental infections by Mycobacterium ulcerans is impaired by the
                        toxin mycolactone", Journal of Immunology {(Baltimore,} Md.: 1950) 184, 2: 947 - 955.
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                     | 4. | 
                     Teixeira, Luzia; Botelho, Ana S; Mesquita, Sandro D; Correia, Alexandra; Cerca, Filipe; Costa, Renata; Sampaio, Paula; Castro, António G; Vilanova, Manuel.  2010. "Plasmacytoid and conventional dendritic cells are early producers of {IL-12} in Neospora caninum-infected mice", Immunology and Cell Biology 88, 1: 79 - 86.
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                     | 5. | 
                     Almeida, A J; Cunha, C; Carmona, J A; Sampaio-Marques, B; Carvalho, A; Malavazi, I; Steensma, H Y; Johnson, D I; Leão, C; Logarinho, E; Goldman, G H; Castro, A G; Ludovico, P; Rodrigues, F.  2009. "Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis", Fungal Genetics and Biology: {FG} \& B 46, 12: 919 - 926.
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                     | 6. | 
                     Oliveira, J T; Santos, T C; Martins, L; Silva, M A; Marques, A P; Castro, A G; Neves, N M; Reis, R L.  2009. "Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously
                        implanted in nude mice", Journal of Tissue Engineering and Regenerative Medicine 3, 7: 493 - 500.
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                     | 7. | 
                     Gaspar, M M; Cruz, A; Fraga, A G; Castro, A G; Cruz, M E. M; Pedrosa, J.  2008. "Developments on drug delivery systems for the treatment of mycobacterial infections", Current Topics in Medicinal Chemistry 8, 7: 579 - 591. | 
                   
                  
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                     | 8. | 
                     Mesquita, Ana R; Correia-Neves, Margarida; Roque, Susana; Castro, António G; Vieira, Paulo; Pedrosa, Jorge; Palha, Joana A; Sousa, Nuno.  2008. "{IL-10} modulates depressive-like behavior", Journal of Psychiatric Research 43, 2: 89 - 97.
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                     | 9. | 
                     Lima-Rodrigues, Manuel; Valle-Fernandes, Ana; Lamas, Nuno; Cruz, Andrea; Baltazar, Fátima; Milanezi, Fernanda; Nunes, Rui; Reis, Rui M; Pedrosa, Jorge; Castro, António G; Almeida, Armando.  2008. "A new model of laryngitis: neuropeptide, cyclooxygenase, and cytokine profile", The Laryngoscope 118, 1: 78 - 86.
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                     | 10. | 
                     Teixeira, L; Botelho, A S; Batista, A R; Meireles, C S; Ribeiro, A; Domingues, H S; Costa, J M. C. D; Castro, A G; Faustino, A M. R; Vilanova, M.  2007. "Analysis of the immune response to Neospora caninum in a model of intragastric infection in mice", Parasite Immunology 29, 1: 23 - 36.
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                     | 11. | 
                     Torrado, Egídio; Fraga, Alexandra G; Castro, António G; Stragier, Pieter; Meyers, Wayne M; Portaels, Françoise; Silva, Manuel T; Pedrosa, Jorge.  2007. "Evidence for an intramacrophage growth phase of Mycobacterium ulcerans", Infection and Immunity 75, 2: 977 - 987.
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                     | 12. | 
                     Torrado, Egídio; Adusumilli, Sarojini; Fraga, Alexandra G; Small, Pamela L. C; Castro, António G; Pedrosa, Jorge.  2007. "Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has
                        implications for the control of infection", Infection and Immunity 75, 8: 3979 - 3988.
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                     | 13. | 
                     Santos, T C; Marques, A P; Silva, S S; Oliveira, J M; Mano, J F; Castro, A G; Reis, R L.  2007. "In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes", Journal of Biotechnology 132, 2: 218 - 226.
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                     | 14. | 
                     Botelho, A S; Teixeira, L; Correia-da-Costa, J M; Faustino, A M. R; Castro, A G; Vilanova, M.  2007. "Neospora caninum: high susceptibility to the parasite in {C57BL/10ScCr} mice", Experimental Parasitology 115, 1: 68 - 75.
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                     | 15. | 
                     Cruz, Andrea; Khader, Shabaana A; Torrado, Egidio; Fraga, Alexandra; Pearl, John E; Pedrosa, Jorge; Cooper, Andrea M; Castro, António G.  2006. "Cutting edge: {IFN-gamma} regulates the induction and expansion of {IL-17-producing} {CD4} T cells during mycobacterial infection", Journal of Immunology {(Baltimore,} Md.: 1950) 177, 3: 1416 - 1420. | 
                   
                  
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                     | 16. | 
                     Neighbors, Margaret; Hartley, Suzanne B; Xu, Xiuling; Castro, Antonio G; Bouley, Donna M; O'Garra, Anne.  2006. "Breakpoints in immunoregulation required for Th1 cells to induce diabetes", European Journal of Immunology 36, 9: 2315 - 2323.
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                     | 17. | 
                     Oliveira, Martinha S; Fraga, Alexandra G; Torrado, Egídio; Castro, António G; Pereira, João P; Filho, Adhemar L; Milanezi, Fernanda; Schmitt, Fernando C; Meyers, Wayne M; Portaels, Françoise; Silva, Manuel T; Pedrosa, Jorge.  2005. "Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice", Infection and Immunity 73, 10: 6299 - 6310.
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                     | 18. | 
                     Castro, A G; Neighbors, M; Hurst, S D; Zonin, F; Silva, R A; Murphy, E; Liu, Y J; O'Garra, A.  2000. "Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only
                        in the presence of lipopolysaccharide", The Journal of Experimental Medicine 192, 10: 1529 - 1534. | 
                   
                  
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                     | 19. | 
                     Castro, A G; Hauser, T M; Cocks, B G; Abrams, J; Zurawski, S; Churakova, T; Zonin, F; Robinson, D; Tangye, S G; Aversa, G; Nichols, K E; Vries, J E.; Lanier, L L; O'Garra, A.  1999. "Molecular and functional characterization of mouse signaling lymphocytic activation molecule {(SLAM):} differential expression
                        and responsiveness in Th1 and Th2 cells", Journal of Immunology {(Baltimore,} Md.: 1950) 163, 11: 5860 - 5870. | 
                   
                  
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                     | 20. | 
                     Castro, A G; Silva, R A; Appelberg, R.  1995. "Endogenously produced {IL-12} is required for the induction of protective T cells during Mycobacterium avium infections in
                        mice", Journal of Immunology {(Baltimore,} Md.: 1950) 155, 4: 2013 - 2019. | 
                   
                  
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                     | 21. | 
                     Castro, A G; Silva, R A; Minóprio, P; Appelberg, R.  1995. "In vivo evidence for a {non-T} cell origin of interleukin-5", Scandinavian Journal of Immunology 41, 3: 288 - 292. | 
                   
                  
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                     | 22. | 
                     Appelberg, R; Castro, A G; Gomes, S; Pedrosa, J; Silva, M T.  1995. "Susceptibility of beige mice to Mycobacterium avium: role of neutrophils", Infection and Immunity 63, 9: 3381 - 3387. | 
                   
                  
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                     | 23. | 
                     Castro, A G; Minóprio, P; Appelberg, R.  1995. "The relative impact of bacterial virulence and host genetic background on cytokine expression during Mycobacterium avium infection
                        of mice", Immunology 85, 4: 556 - 561. | 
                   
                  
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                     | 24. | 
                     Appelberg, R; Sarmento, A; Castro, A G.  1995. "Tumour necrosis factor-alpha {(TNF-alpha)} in the host resistance to mycobacteria of distinct virulence", Clinical and Experimental Immunology 101, 2: 308 - 313. | 
                   
                  
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                     | 25. | 
                     Pedrosa, J; Flórido, M; Kunze, Z M; Castro, A G; Portaels, F; McFadden, J; Silva, M T; Appelberg, R.  1994. "Characterization of the virulence of Mycobacterium avium complex {(MAC)} isolates in mice", Clinical and Experimental Immunology 98, 2: 210 - 216. | 
                   
                  
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                     | 26. | 
                     Appelberg, R; Castro, A G; Silva, M T.  1994. "Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis", Immunology 83, 2: 302 - 307. | 
                   
                  
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                     | 27. | 
                     Appelberg, R; Castro, A G; Pedrosa, J; Silva, R A; Orme, I M; Minóprio, P.  1994. "Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium
                        avium infection", Infection and Immunity 62, 9: 3962 - 3971. | 
                   
                  
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                     | 28. | 
                     Appelberg, R; Castro, A G; Pedrosa, J; Minóprio, P.  1994. "Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice", Immunology 82, 3: 361 - 364. | 
                   
                  
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                     | 29. | 
                     Castro, A G; Esaguy, N; Macedo, P M; Aguas, A P; Silva, M T.  1991. "Live but not heat-killed mycobacteria cause rapid chemotaxis of large numbers of eosinophils in vivo and are ingested by the
                        attracted granulocytes", Infection and Immunity 59, 9: 3009 - 3014. | 
                   
                  
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                  											 (Production indicators) 
            
            
               
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