Amélia Maria Lopes Dias da Silva
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Data da última atualização
»Last update
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23/11/2018 |
Dados pessoais (Personal data)
Nome completo
Full name |
Amélia Maria Lopes Dias da Silva |
Nome em citações bibliográficas
Quoting name |
Silva, Amélia Maria Lopes Dias da |
Categoria profissional
Position |
Professor Auxiliar |
Domínio científico de atuação
Scientific domain |
Ciências Médicas-Ciências da Saúde.
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Endereço profissional
Professional address |
Universidade de Trás-os-Montes e Alto Douro
Escola de Ciências da Vida e do Ambiente
Departamento de Biologia e Ambiente
Departamento de Biologia
Vila Real
5001-801 Vila Real
Portugal
Apartado: 1013
Telefone: (+351)259350106Extensão: 2106
Correio electrónico: amsilva@utad.pt |
Sexo
Gender |
Feminino»Female |
Graus Académicos
(Academic Degrees)
| 2003 |
Doutoramento
Phd |
Bioquímica (especialidade Biofísica Celular).
Universidade de Coimbra,
Portugal.
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| 1992-1995 |
Mestrado
Master degree |
Biologia Celular
(2 anos » years)
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Universidade de Coimbra,
Portugal.
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| 1987-1992 |
Licenciatura
Licentiate degree |
Bioquímica
(5 anos » years)
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Universidade de Coimbra,
Portugal.
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Vínculos profissionais
(Professional Positions)
| Universidade de Trás-os-Montes e Alto Douro |
| Mar/2003-Actual |
Professor Auxiliar |
Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Capítulos de livros publicados
Published book chapters |
| 1. |
Zakharova, Lucia Y; Pashirova, Tatiana N; Fernandes, Ana R; Doktorovova, Slavomira; Martins-Gomes, Carlos; SILVA, Amélia M; Souto, Eliana B. 2018. Self-assembled quaternary ammonium surfactants for pharmaceuticals and biotechnology. In Organic Materials as Smart Nanocarriers for Drug Delivery, ed. Alexandru Mihai Grumezescu , 601 - 618. ISBN: 9780128136638. -: Elsevier.
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| 2. |
Martins-Gomes, Carlos; SILVA, Amélia M. 2018. Western Blot Methodologies for Analysis of In Vitro Protein Expression Induced by Teratogenic Agents. In Teratogenicity Testing, ed. Luís Félix, 191 - 203. ISBN: 978-1-4939-7882-3. New York, NY: Springer New York.
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| 3. |
Teixeira, M.C.; Martins-Gomes, C.; Singh, K.K.; Veiga, F.J.; Silva, A.M.; Souto, E.B.. 2018. Targeting of Lipid/Polymeric (Hybrid) Nanoparticles to the Brain for the Treatment of Degenerative Diseases. In Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors, ed. Prashant Kesharwani and Umesh Gupta, 147 - 168. ISBN: 9780128122181. -: Elsevier.
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| 4. |
Fernandes, Ana R; Martins-Gomes, Carlos; Santini, Antonello; SILVA, Amélia M; Souto, Eliana B. 2018. Psoriasis vulgaris—Pathophysiology of the disease and its classical treatment versus new drug delivery systems. In Design of Nanostructures for Versatile Therapeutic Applications, ed. Alexandru Mihai Grumezescu , 379 - 406. ISBN: 9780128136676. -: Elsevier.
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| 5. |
Fernandes, Ana R; Dias-Ferreira, João; Ferreira-da-Silva, Classius; Severino, Patrícia; Martins-Gomes, Carlos; SILVA, Amélia M; Souto, Eliana B. 2018. Drug nanocrystals: present, past and future. In Applications of Nanocomposite Materials in Drug Delivery, ed. Dr Inamuddin, Abdullah M. Asiri, Ali Mohammad, 239 - 253. ISBN: 9780128137413. -: Elsevier.
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| 6. |
Zielinska, A.; Pereira, I.; Antunes, S.; Veiga, F.J.; Santos, A.C.; Nowak, I.; Silva, A.M.; Souto, E.B.. 2018. Mesoporous silica nanoparticles as drug delivery systems against melanoma. In Design of Nanostructures for Theranostics Applications, ed. Alexandru Mihai Grumezescu, 437 - 466. ISBN: 9780128136690. -: Elsevier.
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| 7. |
Souto, Eliana B; Fernandes, A. R; Ferreira, J. D; da Silva, C. F; Severino, Patrícia; Martins-Gomes, Carlos; SILVA, Amélia M. 2018. Multifunctional Nanocomposites for Biotherapeutic Applications. In Multifunctional Nanocarriers for Contemporary Healthcare Applications, ed. Md. Abul BarkatHarshita A.B.Sarwar BegFarhan J. Ahmad, 328 - 356. ISBN: 9781522547815. -: IGI Global.
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| 8. |
Teixeira, M.C.; Sanchez-Lopez, E.; Espina, M.; Calpena, A.C.; Silva, Amelia M; Veiga, F.J.; Garcia, M.L.; Souto, Eliana B. 2018. Advances in antibiotic nanotherapy. In Emerging Nanotechnologies in Immunology, ed. R. Shegokar, E.B.Souto, William Andrew, 233 - 259. ISBN: 9780323400169. -: Elsevier.
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| 9. |
SILVA, Amélia M; Siopa, João R; Martins-Gomes, Carlos; Teixeira, Maria C; Santos, Dario J; Dos Anjos P. M; Andreani, Tatiana. 2018. New strategies for the treatment of autoimmune diseases using nanotechnologies. In Emerging Nanotechnologies in Immunology, ed. R. Shegokar, E.B.Souto, William Andrew, 135 - 163. ISBN: 9780323400169. -: Elsevier.
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| 10. |
Leal, Fernanda; Taghouti, Meriem; Nunes, Fernando; Silva, Amélia M; Coelho, Ana C; Matos, Manuela. 2017. Thymus Plants: A Review?Micropropagation, Molecular and Antifungal Activity. In Active Ingredients from Aromatic and Medicinal Plants, ed. Hany A. El-Shemy, 107 - 126. ISBN: 978-953-51-2975-2. 1: InTech.
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| 11. |
Sampaio, A.C.; Aires, A.; Souto, E.B.; Silva, A.M.. 2017. Essential Oils, Polyphenols and Glycosides: Secondary Plant Metabolites Against Microbes. In Frontiers in Clinical Drug Research-Anti Infectives, ed. Atta-ur-Rahman , 136 - 186. ISBN: 9781681083698. -: BENTHAM SCIENCE PUBLISHERS.
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| 12. |
Andreani, Tatiana; Severino, Patrícia; de Hollanda, L. M; Vazzana, Monica; Souto, Selma B; Santini, Antonello; Silva, Amélia M; Souto, Eliana B. 2017. Cancer therapies: applications, nanomedicines and nanotoxicology. In Nanostructures for Cancer Therapy, 241 - 260. ISBN: 9780323461443. Elsevier: Elsevier.
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| 13. |
Severino, Patrícia; Fangueiro, Joana F; Chaud, Marco V; Cordeiro, Juliana; Silva, Amelia M; Souto, Eliana B. 2016. Advances in nanobiomaterials for topical administrations: new galenic and cosmetic formulations. In Nanobiomaterials in Galenic Formulations and Cosmetics, 1 - 23. ISBN: 9780323428682. Elsevier: Elsevier.
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| 14. |
Fangueiro, Joana F; Souto, Eliana B; Silva, Amélia M. 2016. Encapsulation of nutraceuticals in novel delivery systems. In Nutraceuticals, 305 - 342. ISBN: 9780128043059. Elsevier: Elsevier.
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| 15. |
Severino, Patrícia; de Hollanda, L. M; Santini, Antonello; Reis, Lucinda V; Souto, Selma B; Souto, Eliana B; Silva, Amélia M. 2016. Advances in nanobiomaterials for oncology nanomedicine. In Nanobiomaterials in Cancer Therapy, 91 - 115. ISBN: 9780323428637. Elsevier: Elsevier.
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| 16. |
Andreani, Tatiana; Souza, Ana L. R; SILVA, Amélia M; Souto, Eliana B. 2012. Sol–Gel Carrier System: A Novel Controlled Drug Delivery. In Patenting Nanomedicines, ed. Eliana B. Souto, 151 - 166. ISBN: 978-3-642-29264-4. Berlin, Heidelberg: Springer Berlin Heidelberg.
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| 17. |
SANTOS, Rosa M; Barbosa, Rui M; Silva, Amélia M; Antunes, Célia M; Rosario, Luis M. 1994. [Ca2+]i-sensitive conductance in the regulation of pancreatic b-cell bursting. In Frontiers of Insulin Secretion and Pancreatic b-cell Research , ed. P. R. Flatt, & Lenzen, S.,, 181 - 186. . U.K.: Smith-Gordon. |
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Artigos em revistas com arbitragem científica
Papers in periodics with scientific refereeing |
| 1. |
Ferreira, Sandrine S; SILVA, Amélia M; Nunes, Fernando M. 2018. "Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds", Industrial Crops and Products 111, 2018: 141 - 148.
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| 2. |
Silva-Abreu, Marcelle; Calpena, Ana C; Espina, Marta; Silva, Amelia M; Gimeno, Alvaro; Egea, María A; García, María L. 2018. "Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy
for Ocular Inflammatory Disorders", Pharmaceutical Research 35, 1: 1 - 14.
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| 3. |
Sánchez-López, Elena; Egea, Maria A; Davis, Benjamin M; Guo, Li; Espina, Marta; Silva, Amelia M; Calpena, Ana C; Souto, Eliana M. B; Ravindran, Nivedita; Ettcheto, Miren; Camins, Antonio; García, Maria L; Cordeiro, Maria F. 2018. "Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma", Small 14, 2: 1701808 - 1701808.
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| 4. |
Martins-Gomes, Carlos; Taghouti, Meriem; Schäfer, Judith; Bunzel, Mirko; SILVA, Amélia M; Nunes, Fernando M. 2018. "Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss.", Journal of Functional Foods 43, 2018: 154 - 164.
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| 5. |
Sánchez-López, Elena; Ettcheto, Miren; Egea, Maria A; Espina, Marta; Cano, Amanda; Calpena, Ana C; Camins, Antoni; Carmona, Nuria; SILVA, Amélia M; Souto, Eliana B; García, Maria L. 2018. "Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization", Journal of Nanobiotechnology 16, 1: 1 - 16.
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| 6. |
Carbone, C.; Martins-Gomes, C.; Pepe, V.; Silva, A.M.; Musumeci, T.; Puglisi, G.; Furneri, P.M.; Souto, E.B.. 2018. "Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy", Colloids and Surfaces B: Biointerfaces 167, 2018: 337 - 344.
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| 7. |
Sario, Sara; SILVA, Amélia M; Gaivão, Isabel. 2018. "Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay
in neuroblasts)", Mutation Research/Genetic Toxicology and Environmental Mutagenesis 831, 2018: 19 - 23.
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| 8. |
Taghouti, Meriem; Martins-Gomes, Carlos; Schäfer, Judith; Félix, Luis M; Santos, João A; Bunzel, Mirko; Nunes, Fernando M; SILVA, Amélia M. 2018. " Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic
compounds ", Food & Function 9, 7: 3617 - 3629.
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| 9. |
Carbone, C.; Martins-Gomes, C.; Caddeo, C.; Silva, A.M.; Musumeci, T.; Pignatello, R.; Puglisi, G.; Souto, E.B.. 2018. "Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles", International Journal of Pharmaceutics 548, 1: 217 - 226.
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| 10. |
Pereira, Irina; Zielinska, Aleksandra; Ferreira, Nuno R; SILVA, Amélia M; Souto, Eliana B. 2018. "Optimization of linalool-loaded solid lipid nanoparticles using experimental factorial design and long-term stability studies
with a new centrifugal sedimentation method", International Journal of Pharmaceutics 549, 1-2: 261 - 270.
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| 11. |
Pereira, Irina; Severino, Patrícia; Santos, Ana C; SILVA, Amélia M; Souto, Eliana B. 2018. "Linalool bioactive properties and potential applicability in drug delivery systems", Colloids and Surfaces B: Biointerfaces 171, 2018: 566 - 578.
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| 12. |
Zielinska, Aleksandra; Martins-Gomes, Carlos; Ferreira, Nuno R; SILVA, Amélia M; Nowak, Izabela; Souto, Eliana B. 2018. "Anti-inflammatory and anti-cancer activity of citral: Optimization of citral-loaded solid lipid nanoparticles (SLN) using
experimental factorial design and LUMiSizer®", International Journal of Pharmaceutics 553, 1-2: 428 - 440.
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| 13. |
Sampaio, A.C.; Mendes, R.J.; Castro, P.G.; Silva, A.M.. 2017. "Solid lipid nanoparticles affect microbial colonization and enzymatic activity throughout the decomposition of alder leaves
in freshwater microcosms", Ecotoxicology and Environmental Safety 135, -: 375 - 380.
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| 14. |
Kiilll, Charlene P; Barud, Hernane S; Santagneli, Sílvia H; Ribeiro, Sidney J. L; SILVA, Amélia M; Tercjak, Agnieszka; Gutierrez, Junkal; Pironi, Andressa M; Gremião, Maria P. D. 2017. "Synthesis and factorial design applied to a novel chitosan/sodium polyphosphate nanoparticles via ionotropic gelation as an
RGD delivery system", Carbohydrate Polymers 157, -: 1695 - 1702.
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| 15. |
Teixeira, M.C.; Severino, P.; Andreani, T.; Boonme, P.; Santini, A.; Silva, A.M.; Souto, E.B.. 2017. "d -alpha-tocopherol nanoemulsions: Size properties, rheological behavior, surface tension, osmolarity and cytotoxicity", Saudi Pharmaceutical Journal 25, 2: 231 - 235.
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| 16. |
Friães, Sofia; SILVA, Amélia M; Boto, Renato E; Ferreira, Diana; Fernandes, José R; Souto, Eliana B; Almeida, Paulo; Ferreira, Luis F. V; Reis, Lucinda V. 2017. "Synthesis, spectroscopic characterization and biological evaluation of unsymmetrical aminosquarylium cyanine dyes", Bioorganic & Medicinal Chemistry 25, 14: 3803 - 3814.
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| 17. |
Queiroz, Marcelo; Oppolzer, David; Gouvinhas, Irene; SILVA, Amélia M; Barros, Ana I; Domínguez-Perles, Raúl. 2017. "New grape stems' isolated phenolic compounds modulate reactive oxygen species, glutathione, and lipid peroxidation in vitro
: Combined formulations with vitamins C and E", Fitoterapia 120, 2017: 146 - 157.
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| 18. |
Sousa, C.; Pereira, I.; Santos, A.C.; Carbone, C.; Kova¿?evic, A.B.; Silva, A.M.; Souto, E.B.. 2017. "Targeting dendritic cells for the treatment of autoimmune disorders", Colloids and Surfaces B: Biointerfaces 158, 2017: 237 - 248.
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| 19. |
Fernandes, A.R.; Ferreira, N.R.; Fangueiro, J.F.; Santos, A.C.; Veiga, F.J.; Cabral, C.; Silva, A.M.; Souto, E.B.. 2017. "Ibuprofen nanocrystals developed by 22 factorial design experiment: A new approach for poorly water-soluble drugs", Saudi Pharmaceutical Journal 25, 8: 1117 - 1124.
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| 20. |
Doktorovova, Slavomira; Souto, Eliana B; SILVA, Amélia M. 2017. " Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN):
in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines ", Pharmaceutical Development and Technology 23, 1: 96 - 105.
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| 21. |
Cañadas, Cristina; Alvarado, Helen; Calpena, Ana C; SILVA, Amélia M; Souto, Eliana B; García, Maria L; Abrego, Guadalupe. 2016. "In vitro, ex vivo and in vivo characterization of PLGA nanoparticles loading pranoprofen for ocular administration", International Journal of Pharmaceutics 511, 2: 719 - 727.
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| 22. |
Domínguez-Perles, Raúl; Guedes, Ana; Queiroz, Marcelo; SILVA, Amélia M; Barros, Ana I. 2016. "Oxidative stress prevention and anti-apoptosis activity of grape (Vitis vinifera L.) stems in human keratinocytes", Food Research International 87, -: 92 - 102.
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| 23. |
Boonme, Prapaporn; Kaewbanjong, Jarika; Amnuaikit, Thanaporn; Andreani, Tatiana; Silva, Amélia; Souto, Eliana. 2016. "Microemulsion and Microemulsion-Based Gels for Topical Antifungal Therapy with Phytochemicals", Current Pharmaceutical Design 22, 27: 4257 - 4263.
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| 24. |
Fujimura, Andressa T; Martinez, Renata M; Pinho-Ribeiro, Felipe A; Lopes Dias S. A. M; Baracat, Marcela M; Georgetti, Sandra R; Verri, Waldiceu A; Chorilli, Marlus; Casagrande, Rubia. 2016. "Resveratrol-Loaded Liquid-Crystalline System Inhibits UVB-Induced Skin Inflammation and Oxidative Stress in Mice", Journal of Natural Products 79, 5: 1329 - 1338.
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| 25. |
Sánchez-López, E.; Egea, M.A.; Cano, A.; Espina, M.; Calpena, A.C.; Ettcheto, M.; Camins, A.; Souto, E.B.; Silva, A.M.; García, M.L.. 2016. "PEGylated PLGA nanospheres optimized by design of experiments for ocular administration of dexibuprofen—in vitro, ex vivo
and in vivo characterization", Colloids and Surfaces B: Biointerfaces 145, -: 241 - 250.
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| 26. |
Santos, Stefanie; SILVA, Amélia M; Matos, Manuela; Monteiro, Sandra M; ¿?lvaro, Ana R. 2016. "Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53", Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 185186, -: 138 - 146.
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| 27. |
Fangueiro, Joana F; Calpena, Ana C; Clares, Beatriz; Andreani, Tatiana; Egea, Maria A; Veiga, Francisco J; Garcia, Maria L; SILVA, Amélia M; Souto, Eliana B. 2016. "Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): In vivo, in vitro
and ex vivo studies", International Journal of Pharmaceutics 502, 1-2: 161 - 169.
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| 28. |
Fangueiro, Joana; Veiga, Francisco; Silva, Amelia; Souto, Eliana. 2016. "Ocular Drug Delivery - New Strategies for Targeting Anterior and Posterior Segments of the Eye", Current Pharmaceutical Design 22, 9: 1135 - 1146.
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| 29. |
Severino, Patrícia; Szymanski, Marcelo; Favaro, Marianna; Azzoni, Adriano R; Chaud, Marco V; Santana, Maria H. A; SILVA, Amélia M; Souto, Eliana B. 2015. "Development and characterization of a cationic lipid nanocarrier as non-viral vector for gene therapy", European Journal of Pharmaceutical Sciences 66, -: 78 - 82.
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| 30. |
Soares, Jorge P; Silva, Amélia M; Fonseca, Sandra; Oliveira, Maria M; Peixoto, Francisco; Gaivão, Isabel; Mota, Maria P. 2015. "How can age and lifestyle variables affect DNA damage, repair capacity and endogenous biomarkers of oxidative stress?", Experimental Gerontology 62, -: 45 - 52.
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| 31. |
Andreani, Tatiana; SILVA, Amélia M; Souto, Eliana B. 2015. "Silica based-matrices: State of the art and new perspectives for therapeutic drug delivery", Biotechnology and Applied Biochemistry n, -: n/a - n/a.
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| 32. |
Fangueiro, Joana F; SILVA, Amélia M; Garcia, Maria L; Souto, Eliana B. 2015. "Current nanotechnology approaches for the treatment and management of diabetic retinopathy", European Journal of Pharmaceutics and Biopharmaceutics, -: na - na.
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| 33. |
Vazzana, M.; Andreani, T.; Fangueiro, J.; Faggio, C.; Silva, C.; Santini, A.; Garcia, M.L.; Silva, A.M.; Souto, E.B.. 2015. "Tramadol hydrochloride: Pharmacokinetics, pharmacodynamics, adverse side effects, co-administration of drugs and new drug
delivery systems", Biomedicine & Pharmacotherapy 70, 2015: 234 - 238.
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| 34. |
Andreani, Tatiana; Miziara, Leonardo; Lorenzón, Esteban N; de Souza, A. L. R; Kiill, Charlene P; Fangueiro, Joana F; Garcia, Maria L; Gremião, Palmira D; SILVA, Amélia M; Souto, Eliana B. 2015. "Effect of mucoadhesive polymers on the in vitro performance of insulin-loaded silica nanoparticles: Interactions with mucin
and biomembrane models", European Journal of Pharmaceutics and Biopharmaceutics 93, -: 118 - 126.
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| 35. |
Andreani, Tatiana; Kiill, Charlene P; de Souza, A. L. R; Fangueiro, Joana F; Doktorovová, Slavomira; Garcia, Maria L; Gramião, Maria P. D; SILVA, Amélia M; Souto, Eliana B. 2015. "Effect of cryoprotectants on the reconstitution of silica nanoparticles produced by sol–gel technology", Journal of Thermal Analysis and Calorimetry 120, 1: 1001 - 1007.
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| 36. |
Andreani, Tatiana; Fangueiro, Joana; Jose, Sajan; Santini, Antonello; Silva, Amelia; Souto, Eliana. 2015. "Hydrophilic Polymers for Modified-Release Nanoparticles: A Review of Mathematical Modelling for Pharmacokinetic Analysis", Current Pharmaceutical Design 21, 22: 3090 - 3096.
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| 37. |
Soares, Jorge P; SILVA, Amélia M; Oliveira, Maria M; Peixoto, Francisco; Gaivão, Isabel; Mota, Maria P. 2015. "Effects of combined physical exercise training on DNA damage and repair capacity: role of oxidative stress changes", AGE 37, 3: 1 - 12.
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| 38. |
Ribeiro, Miguel; Nunes, Fernando M; Guedes, Sofia; Domingues, Pedro; SILVA, Amélia M; Carrillo, Jose M; Rodriguez-Quijano, Marta; Branlard, Gérard; Igrejas, Gilberto. 2015. "Efficient chemo-enzymatic gluten detoxification: reducing toxic epitopes for celiac patients improving functional properties", Scientific Reports 5, -: 18041 - 18041.
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| 39. |
Soares, Jorge P; Silva, Ana I; SILVA, Amélia M; Almeida, Vanessa; Teixeira, João P; Matos, Manuela; Gaivão, Isabel; Mota, Maria P. 2015. " Effects of physical exercise training in DNA damage and repair activity in humans with different genetic polymorphisms
of hOGG1 (Ser326Cys) ", Cell Biochemistry and Function 33, 8: 519 - 524.
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| 40. |
Macedo, Ana S; Quelhas, Sara; SILVA, Amélia M; Souto, Eliana B. 2014. " Nanoemulsions for delivery of flavonoids: formulation and in vitro release of rutin
as model drug ", Pharmaceutical Development and Technology 19, 6: 677 - 680.
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| 41. |
Doktorovova, Slavomira; Shegokar, Ranjita; Fernandes, Lisete; Martins-Lopes, Paula; SILVA, Amélia M; Müller, Rainer H; Souto, Eliana B. 2014. "Trehalose is not a universal solution for solid lipid nanoparticles freeze-drying", Pharmaceutical Development and Technology 19, 8: 922 - 929.
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| 42. |
Doktorovova, Slavomira; SILVA, Amélia M; Gaivão, Isabel; Souto, Eliana B; Teixeira, João P; Martins-Lopes, Paula. 2014. "Comet assay reveals no genotoxicity risk of cationic solid lipid nanoparticles", Journal of Applied Toxicology 34, 4: 395 - 403.
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| 43. |
Monteiro-Cardoso, Vera F; SILVA, Amélia M; Oliveira, Maria M; Peixoto, Francisco; Videira, Romeu A. 2014. "Membrane lipid profile alterations are associated with the metabolic adaptation of the Caco-2 cells to aglycemic nutritional
condition", Journal of Bioenergetics and Biomembranes 46, 1: 45 - 57.
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| 44. |
Fangueiro, Joana F; Andreani, Tatiana; Egea, Maria A; Garcia, Maria L; Souto, Selma B; SILVA, Amélia M; Souto, Eliana B. 2014. "Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity", International Journal of Pharmaceutics 461, 1-2: 64 - 73.
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| 45. |
Souza, Ana L. R.; Andreani, Tatiana; de Oliveira, R. N; Kiill, Charlene P; Santos, Fernanda K.; Allegretti, Silmara M; Chaud, Marco V; Souto, Eliana B; SILVA, Amélia M; Gremião, Maria P. D. 2014. "In vitro evaluation of permeation, toxicity and effect of praziquantel-loaded solid lipid nanoparticles against Schistosoma
mansoni as a strategy to improve efficacy of the schistosomiasis treatment", International Journal of Pharmaceutics 463, 1: 31 - 37.
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| 46. |
Doktorovova, Slavomira; Souto, Eliana B; SILVA, Amélia M. 2014. "Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers – A systematic review of in vitro data", European Journal of Pharmaceutics and Biopharmaceutics 87, 1: 1 - 18.
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| 47. |
Sousa, Cristina P; Azevedo, Jorge T; SILVA, Amélia M; Viegas, Carlos A; Reis, Rui L; Gomes, Manuela E; Dias, Isabel R. 2014. "Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep", Acta Veterinaria Hungarica 62, 2: 205 - 214.
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| 48. |
Doktorovová, Slavomira; Santos, Dario L; Costa, Inês; Andreani, Tatiana; Souto, Eliana B; SILVA, Amélia M. 2014. "Cationic solid lipid nanoparticles interfere with the activity of antioxidant enzymes in hepatocellular carcinoma cells", International Journal of Pharmaceutics 471, 1-2: 18 - 27.
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| 49. |
Severino, Patrícia; Andreani, Tatiana; Jäger, Alessandro; Chaud, Marco V; Santana, Maria H. A; SILVA, Amélia M; Souto, Eliana B. 2014. "Solid lipid nanoparticles for hydrophilic biotech drugs: Optimization and cell viability studies (Caco-2 & HEPG-2 cell lines)", European Journal of Medicinal Chemistry 81, -: 28 - 34.
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| 50. |
Andreani, Tatiana; Souza, Ana L. R.; Kiill, Charlene P; Lorenzón, Esteban N; Fangueiro, Joana F; Calpena, Ana C; Chaud, Marco V; Garcia, Maria L; Gremião, Maria P. D; SILVA, Amélia M; Souto, Eliana B. 2014. "Preparation and characterization of PEG-coated silica nanoparticles for oral insulin delivery", International Journal of Pharmaceutics 473, 1-2: 627 - 635.
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| 51. |
Fangueiro, Joana F; Parra, Alexander; SILVA, Amélia M; Egea, Maria A; Souto, Eliana B; Garcia, Maria L; Calpena, Ana C. 2014. "Validation of a high performance liquid chromatography method for the stabilization of epigallocatechin gallate", International Journal of Pharmaceutics 475, 1-2: 181 - 190.
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| 52. |
Andreani, Tatiana; Kiill, Charlene P; Souza, Ana L. R.; Fangueiro, Joana F; Fernandes, Lisete; Doktorovová, Slavomira; Santos, Dario L; Garcia, Maria L; Gremião, Maria P. D; Souto, Eliana B; SILVA, Amélia M. 2014. "Surface engineering of silica nanoparticles for oral insulin delivery: Characterization and cell toxicity studies", Colloids and Surfaces B: Biointerfaces 123, -: 916 - 923.
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| 53. |
Fangueiro, Joana F; Andreani, Tatiana; Fernandes, Lisete; Garcia, Maria L; Egea, Maria A; SILVA, Amélia M; Souto, Eliana B. 2014. "Physicochemical characterization of epigallocatechin gallate lipid nanoparticles (EGCG-LNs) for ocular instillation", Colloids and Surfaces B: Biointerfaces 123, -: 452 - 460.
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| 54. |
Silva, Amélia M; Miranda, Andreia; Fernandes, Elisabete; Santos, Susana; Fraga, Irene; Santos, Dario L; Dias, Albino A; Bezerra, Rui M. 2013. "Endopolysaccharides from Ganoderma resinaceum, Phlebia rufa, and Trametes versicolor Affect Differently the Proliferation
Rate of HepG2 Cells", Applied Biochemistry and Biotechnology 169, 6: 1919 - 1926.
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| 55. |
Santos, Isis S; Ponte, Bruno M; Boonme, Prapaporn; Silva, Amélia M; Souto, Eliana B. 2013. "Nanoencapsulation of polyphenols for protective effect against colon–rectal cancer", Biotechnology Advances 31, 5: 514 - 523.
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| 56. |
Andreani, Tatiana; Sofia Macedo, A; F. Ferreira, S; M. Silva, A; Rosmaninho, Aristoteles; B. Souto, E. 2012. "Topical Targeting Therapies for Sexually Transmitted Diseases", Current Nanoscience 8, 4: 486 - 490.
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| 57. |
Severino, Patrícia; Andreani, Tatiana; Macedo, Ana S; Fangueiro, Joana F; Santana, Maria H. A; Silva, Amélia M; Souto, Eliana B. 2012. "Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery", Journal of Drug Delivery 2012, 2012: 1 - 10.
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| 58. |
Doktorovova, S.; Shegokar, R.; Martins-Lopes, P.; Silva, A.M.; Lopes, C.M.; Müller, R.H.; Souto, E.B.. 2012. "Modified Rose Bengal assay for surface hydrophobicity evaluation of cationic solid lipid nanoparticles (cSLN)", European Journal of Pharmaceutical Sciences 45, 5: 606 - 612.
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| 59. |
Souza, Ana L. R; Andreani, Tatiana; Nunes, Fernando M; Cassimiro, Douglas L; Almeida, Adélia E; Ribeiro, Clóvis A; Sarmento, Victor H. V; Gremião, Maria P. D; Silva, Amélia M; Souto, Eliana B. 2011. "Loading of praziquantel in the crystal lattice of solid lipid nanoparticles", Journal of Thermal Analysis and Calorimetry 108, 1: 353 - 360.
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| 60. |
Doktorovova, S.; Shegokar, R.; Rakovsky, E.; Gonzalez-Mira, E.; Lopes, C.M.; Silva, A.M.; Martins-Lopes, P.; Muller, R.H.; Souto, E.B.. 2011. "Cationic solid lipid nanoparticles (cSLN): Structure, stability and DNA binding capacity correlation studies", International Journal of Pharmaceutics 420, 2: 341 - 349.
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| 61. |
Dias, I.R.; Viegas, C.A.; Silva, A.M.; Pereira, H.F.; Sousa, C.P.; Carvalho, P.P.; Cabrita, A.S.; Fontes, P.J.; Silva, S.R.; Azevedo, J.M.T.. 2010. "Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from the northeast of Portugal", ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA 62, 2: 265 - 272.
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| 62. |
Souto, Eliana B; Martins-Lopes, Paula; Lopes, Carla M; Gaivão, Isabel; Silva, Amélia M; Guedes-Pinto, Henrique. 2009. "A Note on Regulatory Concerns and Toxicity Assessment in Lipid-Based Delivery Systems (LDS)", Journal of Biomedical Nanotechnology 5, 4: 317 - 322.
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| 63. |
 Misler, Stanley; Zhou, Zhuan; Dickey, Adam S; Silva, Amelia M; Pressel, David M; Barnett, David W. 2009. " Electrical activity and exocytotic correlates of biphasic insulin secretion from ß-cells of canine islets of
Langerhans: Contribution of tuning two modes of Ca 2+ entry-dependent exocytosis to two modes of
glucose-induced electrical activity ", Channels 3, 3: 181 - 193.
 |
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| 64. |
Misler, Stanley; Silva, Amelia M; Barnett, David W; Dickey, Adam S. 2009. "Phasic and tonic modes of depolarization-exocytosis coupling in ß-cells of porcine islets of Langerhans", Channels 3, 2: 101 - 109.
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| 65. |
Silva, Amelia M; Dickey, Adam S; Barnett, David W; Misler, Stanley. 2009. "Ion channels underlying stimulus-exocytosis coupling and its cell-to-cell heterogeneity in ß-cells of transplantable porcine
islets of Langerhans", Channels 3, 2: 91 - 100.
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| 66. |
Rosário, Luís M; BARBOSA, Rui M; ANTUNES, Célia M; BALDEIRAS, Inês E; SILVA, Amélia M; TOMÉ, Ângelo R; SANTOS, Rosa M. 2008. "Regulation by Glucose of Oscillatory Electrical Activity and 5-HT/Insulin Release from Single Mouse Pancreatic Islets in Absence
of Functional KATP Channels", Endocrine Journal 55, 4: 639 - 650.
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| 67. |
Silva, Amélia M; Rodrigues, Ricardo J; Tomé, Ângelo R; Cunha, Rodrigo A; Misler, Stanley; Rosário, Luís M; Santos, Rosa M. 2008. "Electrophysiological and Immunocytochemical Evidence for P2X Purinergic Receptors in Pancreatic ß Cells", Pancreas 36, 3: 279 - 283.
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| 68. |
Morais, Raul; Valente, A.; Almeida, J.C.; Silva, Amélia M; Soares, Salviano; Reis, M.J.C.S.; Valentim, R.; Azevedo, Jorge. 2006. "Concept study of an implantable microsystem for electrical resistance and temperature measurements in dairy cows, suitable
for estrus detection", Sensors and Actuators A: Physical 132, 1: 354 - 361.
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| 69. |
Silva, A. M; Liu-Gentry, J.; Dickey, A.S.; Barnett, D.W.; Misler, S.. 2005. "alpha-Latrotoxin increases spontaneous and depolarization-evoked exocytosis from pancreatic islet beta-cells", JOURNAL OF PHYSIOLOGY-LONDON 565, 3: 783 - 799.
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| 70. |
Barbosa, Rui M; Silva, Amelia M; Tome, Angelo R; Stamford, Jonathan A; Santos, Rosa M; Rosario, Luis M. 1998. "Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics", JOURNAL OF PHYSIOLOGY-LONDON 510, 1: 135 - 143.
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| 71. |
Santos, R. M; Barbosa, R.M.; C.M., Antunes.; Silva, A.M.; Salgado, A.P.; Abrunhosa, A.J.; Pereira, F.C.; Seiça, R.M.; Rosário, L.M.. 1997. "Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular
pH and modulation by glucose metabolism", ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, 426: 33 - 45. |
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| 72. |
Barbosa, Rui M; Silva, Amélia M; Tome, Angelo R; Stamford, Jonathan A; Santos, Rosa M; Rosario, Luis M. 1996. "Real Time Electrochemical Detection of 5-HT/Insulin Secretion from Single Pancreatic Islets: Effect of Glucose and K+Depolarization", Biochemical and Biophysical Research Communications 228, 1: 100 - 104.
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| 73. |
Salgado, A.P.; Silva, A.M.; Santos, R. M; Rosário, L.M.. 1996. "Multiphasic action of glucose and alpha-keto isocaproic acid on the intracellular pH of isolated mouse pancreatic beta-cells.", Journal of Biological Chemistry 271, 15: 8738 - 8467. |
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| 74. |
Silva, Amélia M; Rosario, Luis M; Santos, Rosa M. 1994. "Background Ca2+ influx mediated by a dihydropyridine- and voltage insensitive channel in pancreatic *-cells: modulation by
Ni2+, diphenylamine-2-carboxylate and glucose metabolism. ", Journal of Biological Chemistry 269, 25: 17095 - 17103. |
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| 75. |
Rosario, Luis M; Barbosa, Rui M; Antunes, Célia M; Silva, Amélia M; Abrunhosa, Antero J; Santos, Rosa M. 1993. "Bursting electrical activity in pancreatic beta-cells: evidence that the channel underlying the burst is sensitive to Ca2+
influx through L-type Ca2+ channels", Pflugers Archiv European Journal of Physiology 424, 5-6: 439 - 447.
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| 76. |
Santos, Rosa M; Barbosa, Rui M; Silva, Amélia M; Antunes, Célia M; Rosario, Luis M. 1992. "High external Ca2+ levels trigger membrane potential oscillations in mouse pancreatic ß-cells during blockade of K(ATP) channels", Biochemical and Biophysical Research Communications 187, 2: 872 - 879.
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Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Produção científica
Scientific production |
93 |
Livros e capítulos
Books and book chapters |
17 |
Capítulos de livros publicados
Published book chapters |
17 |
Artigos científicos em revistas
Papers in periodics |
76 |
Com arbitragem científica
With scientific refereeing |
76 |
|
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