Helena Maria Lourenço Carvalheiro
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Data da última atualização
»Last update
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22/12/2014 |
Dados pessoais (Personal data)
Nome completo
Full name |
Helena Maria Lourenço Carvalheiro |
Nome em citações bibliográficas
Quoting name |
Carvalheiro, Helena Maria Lourenço |
Domínio científico de atuação
Scientific domain |
Ciências Médicas-Ciências da Saúde. Ciências Naturais-Ciências Biológicas. Ciências Médicas-Biotecnologia Médica.
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Endereço profissional
Professional address |
Centro de Neurociências e Biologia Celular Metabolismo, envelhecimento e doença Farmacologia Imuno-metabólica Rua Larga, Faculdade de Medicina, Pólo I, 1º andar 3004-50 Coimbra Portugal Correio electrónico: helena.c@ci.uc.pt |
Sexo
Gender |
Feminino»Female |
Graus Académicos
(Academic Degrees)
2007-2009 |
Mestrado Master degree |
Biologia Celular e Molecular
(2 anos » years)
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Universidade de Coimbra,
Portugal.
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2003-2007 |
Licenciatura Licentiate degree |
Biologia
(4 anos » years)
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Universidade de Coimbra,
Portugal.
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Vínculos profissionais
(Professional Positions)
Jan/2010-Actual |
Estagiário Investigador |
Ago/2009-Dez/2009 |
Assistente de Investigação |
Jan/2008-Jan/2009 |
Estagiário Investigador |
Projetos de Investigação (Research projects)
Participação como Doutorando Participation as Phd student |
2011-2015 Functional and molecular analysis of CD8+ T cell subsets in Rheumatoid Arthritis patients. |
Referência do projeto»Project reference: CD8TNF.
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2010-2013 The role of CD8+ T cells in the pathogenesis of Rheumatoid Arthritis |
Referência do projeto»Project reference: SFRH/BD/60467/2009.
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Participação como Mestrando Participation as Master degree student |
2007-2010 Intracellular signaling pathways involved in glioblastoma cells proliferation |
Referência do projeto»Project reference: 10/2006.
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2006-2009 Assessement of intratumoral genetic heterogeneity in gliomas by combined interphase FISH, cDNA microarray and imunophenotype
impact on the clinical and biological behaviour of the disease
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Referência do projeto»Project reference: 68708/2005.
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Línguas (Languages)
Compreende Understandig |
Português (Bem), Francês (Bem), Alemão (Razoavelmente), Espanhol (Bem), Inglês (Bem), Italiano (Bem). |
Fala Speaking |
Português (Bem), Francês (Bem), Alemão (Razoavelmente), Espanhol (Razoavelmente), Inglês (Bem), Italiano (Razoavelmente). |
Lê Reading |
Português (Bem), Francês (Bem), Alemão (Razoavelmente), Espanhol (Pouco), Inglês (Bem), Italiano (Bem). |
Escreve Writing |
Português (Bem), Francês (Bem), Alemão (Razoavelmente), Espanhol (Pouco), Inglês (Bem), Italiano (Razoavelmente). |
Prémios e títulos (Awards Prizes, and Honours)
2014 |
EULAR Bursary,
EULAR.
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2011 |
EFIS grant ,
EFIS.
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2010 |
Travel award,
Sociedade Portuguesa de Imunologia.
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Membro de Associações Profissionais/Científicas (Professional/Scientific Association membership)
Jan/2012 - Set/2014 |
EMEUNET - Emerging EULAR Network, Membro.
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Dez/2011 - Set/2014 |
Autoimmunity Network, Membro.
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Out/2009 - Jun/2014 |
Sociedade Portuguesa de Imunologia, Membro.
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Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Artigos em revistas sem arbitragem científica Papers in periodics without scientific refereeing |
1. |
Rodrigues-Sousa, T; Ladeirinha, AF; Santiago, AR; Carvalheiro, H; Raposo, B; Alarcao, A; Cabrita, AS; Holmdahl, R; Carvalho, L; Souto-Carneiro, MM. 2014. "Deficient Production of Reactive Oxygen Species Leads to Severe Chronic DSS-Induced Colitis in Ncf1/p47phox-Mutant Mice", PLoS ONE 9, 5: e97532 - e97532.
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2. |
Carvalheiro, H; da Silva, J; Souto-Carneiro, MM. 2013. "Potential roles for CD8+ T cells in rheumatoid arthritis", Autoimmunity Reviews 12, 3: 401 - 409.
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3. |
Carmo, A; Carvalheiro, H; Crespo, I; Nunes, I; Lopes, MC. 2011. "Effect of temozolomide on the U-118 glioma cell line", Oncology Letters 2, 6: 1165 - 1170.
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4. |
Carmo, A; Patricio, I; Cruz, MT; Carvalheiro, H; Oliveira, CR; Lopes, MC. 2010. "CXCL12/CXCR4 promotes motility and proliferation of glioma cells", Cancer Biology & Therapy 9, 1: 56 - 65.
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5. |
Raposo, B; Rodrigues-Santos, P; Carvalheiro, H; Água-Doce, AM; Carvalho, L; da Silva, J; Graça, L; Souto-Carneiro, MM. 2010. "Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis", Arthritis & Rheumatism 62, 10: 2953 - 2962.
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Trabalhos completos/resumidos em eventos sem arbitragem científica Papers in conference proceedings without scientific refereeing |
1. |
Carvalheiro, H; Duarte, C; Silva-Cardoso, S; da Silva, J; Souto-Carneiro, MM. 2014. " CD8+ T cell profiles in patients with rheumatoid arthritis and their relation with disease activity", Trabalho apresentado em 34th European Workshop for Rheumatology Research, In Annals of the rheumatic diseases, Lisbon. |
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2. |
Rodrigues-Sousa, T; Carvalheiro, H; Ladeirinha, AF; Alarcao, A; Cabrita, AS; Carvalho, L; Souto-Carneiro, MM. 2012. " Deficient production of reactive oxygen species leads to a chronic DSS-induced colitis in Ncf1-deficient B10.Q mice", Trabalho apresentado em European Congress of Immunology, In Immunology, Glasgow. |
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3. |
Carvalheiro, H; Souto-Carneiro, MM. 2012. "Monoclonal anti-CD8 therapy induces disease amelioration in collagen-induced arthritis in the B10.Q mouse model", Trabalho apresentado em European Congress of Immunology, In Immunology, Glasgow. |
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4. |
Abreu, M; Carvalheiro, H; Duarte, C; da Silva, J; Souto-Carneiro, MM. 2011. "Expression of CD62L, CD27 and CD11b define a marked cytotoxic effector role for NK cells in rheumatoid arthritis", Trabalho apresentado em 31st European Workshop for Rheumatology Research, In Annals of Rheumatic Diseases, Amsterdam. |
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5. |
Carvalheiro, H; Antunes, D; Duarte, C; Silva-Cardoso, S; Rodrigues-Sousa, T; da Silva, J; Souto-Carneiro, MM. 2011. "Characterisation of CD8+ T cell subsets in the synovial fluid and peripheral blood of rheumatoid arthritis patients", Trabalho apresentado em 1st European Workshop for Rheumatology Research, In Annals of Rheumatic Diseases, Amsterdam. |
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6. |
Carvalheiro, H; Carmo, A; Abreu, M; Lopes, MC. 2010. "Signaling pathways involved in glioblastoma resistance to temozolomide", Trabalho apresentado em 15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine, In International Journal of Molecular Medicine, Loutraki. |
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7. |
Carvalheiro, H; Carmo, A; Crespo, I; Lopes, MC. 2009. "Study of glioma cell survival in response to temozolomide treatment", Trabalho apresentado em Third International Congress of Molecular Medicine, In IUMB Life, Istanbul.
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8. |
Carmo, A; Carvalheiro, H; Cruz, MT; Lopes, MC. 2009. "CXCL12/CXCR4 modulates glioma cell survival and motility", Trabalho apresentado em Third International Congress of Molecular Medicine, In IUMB Life, Istanbul.
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9. |
Carmo, A; Carvalheiro, H; Cruz, MT; Lopes, MC. 2008. "AKT activation mediates the adhesion and migration of glioma cells", Trabalho apresentado em XVIII Congreso de la Asociación Latinoamericana de Farmacología, In Revista de Farmacologia de Chile, Coquimbo. |
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Apresentação oral de trabalho Oral work presentation |
1. |
Carvalheiro, H; Duarte, C; Silva-Cardoso, S; da Silva, J; Souto-Carneiro, MM. CD8+T cell profiles in patients with rheumatoid arthritis and their relation with disease activity,34th European Workshop for Rheumatology Research,Lisboa,2014 (Poster).
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2. |
Carvalheiro, H; Duarte, C; Silva-Cardoso, S; Souto-Carneiro, MM; da Silva, J. The role of CD8+ T cells in Rheumatoid Arthritis,4th PF2MUC Symposium - Personalized Medicine: Myth or Reality,2013 (Comunicação). |
3. |
Carvalheiro, H. The role of CD8+ T cells in autoimmunity. Focus in arthritis,XIII Congresso da Sociedade Ibérica de Citometria,Aveiro,2013 (Conferência ou palestra). |
4. |
Carvalheiro, H; Souto-Carneiro, MM. Anti-CD8 Therapy Induces Disease Amelioration in Collagen-induced Arthritis in the B10.Q Mouse Model,European Congress of Immunology,Glasgow,2012 (Poster). |
5. |
Carvalheiro, H; Silva-Cardoso, S; Duarte, C; Rodrigues-Sousa, T; da Silva, J; Souto-Carneiro, MM. Alterations in CD8+T cell subsets in synovial fluid and peripheral blood of patients with Rheumatoid Arthritis.,XXXVIII Annual Meeting Of The Portuguese Society Of Immunology,Porto,2012 (Poster). |
6. |
Abreu, M; Carvalheiro, H; Rodrigues-Sousa, T; Domingos, A; Rodrigues-Santos, P; Souto-Carneiro, MM. Alterations in the peripheral blood B cell subpopulations of multidrug resistant tuberculosis patients,XXXVIII Annual Meeting Of The Portuguese Society Of Immunology,Porto,2012 (Poster). |
7. |
Carvalheiro, H; Silva-Cardoso, S; Duarte, C; Rodrigues-Sousa, T; Antunes, D; da Silva, J; Souto-Carneiro, MM. CD8+ T cells in rheumatoid arthritis - differences between remission and active disease,Annual European Congress of Rheumatology EULAR 2012,Berlim,2012 (Outra). |
8. |
Rodrigues-Sousa, T; Carvalheiro, H; Ladeirinha, AF; Alarcao, A; Cabrita, AS; Carvalho, L; Souto-Carneiro, MM. Deficient production of reactive oxygen species leads to a chronic DSS-induced colitis in Ncf1-deficient B10.Q mice,European Congress of Immunology,Glasgow,2012 (Poster). |
9. |
Rodrigues-Sousa, T; Ladeirinha, AF; Carvalheiro, H; Raposo, B; Alarcao, A; Cabrita, AS; Carvalho, L; Rodrigues-Santos, P; Souto-Carneiro, MM. Ncf1/p47phox-mutant B10.Q mice develop a severe chronic DSS-induced colitis as a consequence of deficient production of reactive
oxygen species,XXXVIII Annual Meeting Of The Portuguese Society Of Immunology,Porto,2012 (Poster). |
10. |
Rodrigues-Sousa, T; Carvalheiro, H; Ladeirinha, AF; Alarcao, A; Cabrita, AS; Carvalho, L; Souto-Carneiro, MM. Deficient production of reactive oxygen species leads to a chronicDSS-induced colitis inNcf1-deficient B10.Q mice,2nd PF2MUC Symposium, Changing Paradigms of Science,Coimbra,2012 (Poster). |
11. |
Carvalheiro, H; Antunes, D; Duarte, C; Silva-Cardoso, S; Rodrigues-Sousa, T; da Silva, J; Souto-Carneiro, MM. Characterisation of CD8+ T cell subsets in the synovial fluid and peripheral blood of rheumatoid arthritis patients,31st European Workshop for Rheumatology Research,Amesterdão,2011 (Poster). |
12. |
Abreu, M; Carvalheiro, H; Duarte, C; da Silva, J; Souto-Carneiro, MM; Rodrigues-Santos, P. Expression of CD62L, CD27 and CD11b define a marked cytotoxic effector role for NK cells in rheumatoid arthritis,31st European Workshop for Rheumatology Research,Amesterdão,2011 (Poster). |
13. |
Carvalheiro, H; Raposo, B; Souto-Carneiro, MM. Accumulation of activated effector CD8+ T cells in the blood of mice with collagen-induced arthritis,5th ENII EFIS/EJI Immunology Summer School 2010,Capo Caccia,2010 (Poster). |
14. |
Carvalheiro, H; Antunes, D; Duarte, C; Silva-Cardoso, S; Rodrigues-Sousa, T; da Silva, J. Alterations in CD8+ T cell subsets in synovial fluid and peripheral blood of patients with Rheumatoid Arthritis,CNBC Annual Meeting 2010,Coimbra,2010 (Comunicação). |
15. |
Teixeira, AM; Carvalheiro, H; Souto-Carneiro, MM; Holmdahl, R; Rodrigues-Santos, P. Ncf1 mutant B10.Q mice with defective Reactive Oxygen Species (ROS) production show impaired peripheral NK cell differentiati,12th Meeting of the Society of Natural Immunity, NK2010,Cavtat-Dubrovnik,2010 (Poster). |
16. |
Carmo, A; Carvalheiro, H; Lopes, MC. Signaling pathways involved in glioblastoma resistance to temozolomide,15th Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine,Loutraki,2010 (Poster). |
17. |
Carvalheiro, H; Rodrigues-Sousa, T; Silva-Cardoso, S; Weinmann, P; Souto-Carneiro, MM. ROS deficient mice present a delayed immune response in zymosan-induced peritonitis,XXXVI SPI Annual Meeting,Braga,2010 (Comunicação). |
18. |
Carvalheiro, H; Balseiro, S; Rodrigues-Sousa, T; Antunes, D; Silva-Cardoso, S; Souto-Carneiro, MM; Rodrigues-Santos, P. The impact of cytokine and toll-like receptor gene polymorphisms in rheumatoid arthritis,XXXVI SPI Annual Meeting 2010,Braga,2010 (Poster). |
19. |
Carvalheiro, H; Carmo, A; Crespo, I; Lopes, MC. Study of glioma cell survival in response to temozolomide treatment,Turkish Society of Molecular Medicine, Third International Congress of Molecular Medicine,Istanbul,2009 (Poster). |
20. |
Carmo, A; Carvalheiro, H; Cruz, MT; Lopes, MC. CXCL12/CXCR4 modulates glioma cell survival and motility,Turkish Society of Molecular Medicine, Third International Congress of Molecular Medicine,Istanbul,2009 (Poster). |
21. |
Carmo, A; Carvalheiro, H; Cruz, MT; Lopes, MC. AKT activation mediates the adhesion and migration of glioma cells,XVIII Congreso de la Asociación Latinoamericana de Farmacología.,Coquimbo,2008 (Poster). |
Dados Complementares (Additional data)
Dissertação de Mestrado Master degree dissertation |
1. |
Sandra Cristina Silva Cardoso, Caracterização fenótipica e funcional de subpopulações de linfócitos T CD8+ em Sangue Periférico e Líquido Sinovial de doentes
de Artrite Reumatóide e quantificação de Citocinas e Quimiocinas no Soro desses doentes, 2011. Dissertação (Biologia Celular e Molecular) - Instituto Politécnico de Bragança (Co-orientador). |
1. |
José Rui Simplício, Functional analysis of CD8+ T cells in Rheumatoid Arthritis, 2014. Dissertação (Bioquímica) - Universidade de Coimbra (Orientador). |
Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Produção técnica
Technical production |
Dados complementares
data |
Produção científica Scientific production |
14 |
Artigos científicos em revistas Papers in periodics |
5 |
Sem arbitragem científica Without scientific refereeing |
5 |
Trabalhos em eventos Papers in conference proceedings |
9 |
Sem arbitragem científica Without scientific refereeing |
9 |
Produção técnica Technical production |
21 |
Outros tipos de produção técnica Other technical production |
21 |
Dados complementares (Additional data) |
2 |
Orientações Orientations |
2 |
Visualizações do curriculum [
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