Paulo Pereira received his Ph.D. from the Catholic University of Portugal (Biotechnology, specialization Microbiology) Dr. Pereira has been recruited as a quality and laboratory utilization expert for seminars and laboratory professional meeting throughout Europe 22+ years of experience in medical laboratory, having held key scientific leadership roles: 9+ years as medical technician 12+ years as researcher 3+ years as consultant of a metrology laboratory in a national transfusion and transplantation institute based on ISO/IEC 17025 specifications 16+ years as a consultant and auditor of quality management systems and technical requirements (ISO 9001, ISO/IEC 17025, and ISO 15189) in a national transfusion and transplantation institute 9+ years as a quality manager and the national coordinator of a quality management department in a national transfusion and transplantation institute 5+ years as a quality control teacher in the School of Health Technology, Lisbon Polytechnic Institute and the Medical School, Nova University of Lisbon Dr. Pereira is the author of several peer-review scientific and technical articles, and indexed book chapters. He serves as both reviewer scientific and technical articles and as a member of Editorial Boards Specialties: Expert in quality control of medical laboratory tests: verification, validation, internal quality control, external quality assessment, measurement uncertainty, and reference intervals Successful practice of CLSI protocols Sampling methodologies and statistical quality control applied to the blood components production Blood and plasma screening tests Risk management GLP in medical laboratory and GMP on the manufacture of blood components Successfully leading Quality teams Leading highly effective cross-functional teams through strong leadership skills ORCID: http://orcid.org/0000-0001-5945-7732 ResearcherID: http://www.researcherid.com/rid/M-4106-2016 ResearchGate: http://www.researchgate.net/profile/Paulo_Pereira11 LinkedIn: http://www.linkedin.com/in/pauloarpereira
Endereço de acesso a este CV: http://www.degois.pt/visualizador/curriculum.jsp?key=4441613804709966

Nome completo Full name	Paulo António Rodrigues Pereira
Nome em citações bibliográficas Quoting name	Pereira, Paulo

Endereço profissional Professional address

Instituto Português do Sangue e da Transplantação, I.P. Gabinete de Investigação, Inovação e Desenvolvimento Gabinete de Gestão da Qualidade Av. Miguel Bombarda 6 Lisboa 1000-208 Lisboa Portugal Telefone: (+351)210063047 Fax: (+351)210063070 Correio electrónico: paulo.pereira@ipst.min-saude.pt Homepage: http://www.ipst.pt

Sexo Gender

Masculino»Male

2015-2016	Doutoramento Phd
Doutoramento em Biotecnologia, Especialidade de Microbiologia (1 anos » years) . Universidade Católica Portuguesa, Portugal.

2000-2005	Mestrado Master degree
Engenharia da Saúde (3 anos » years) . Universidade Católica Portuguesa, Portugal.

Compreende Understandig	Inglês (Bem).
Fala Speaking	Inglês (Bem).
Lê Reading	Inglês (Bem).
Escreve Writing	Inglês (Bem).

Artigos em revistas sem arbitragem científica Papers in periodics without scientific refereeing

1.	Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard. 2015. "Evaluation of the measurement uncertainty in screening immunoassays in blood establishments: Computation of diagnostic accuracy models ", Transfusion and Apheresis Science  52, 1: 35 - 41. The European Union regulation for blood establishments does not require the evaluation of measurement uncertainty in virology screening tests, which is required by ISO 15189 guideline following GUM principles. GUM modular approaches have been discussed by medical laboratories researchers but no consensus has been achieved regarding practical application. Meanwhile, the application of empirical approaches fulfilling GUM principles has gained support. Blood establishments' screening tests accredited by ISO 15189 need to select an appropriate model even GUM models are intended uniquely for quantitative examination procedures. Alternative (to GUM) models focused on probability have been proposed in medical laboratories' diagnostic tests. This article reviews, discusses and proposes models for diagnostic accuracy in blood establishments' screening tests. The output of these models is an alternative to VIM's measurement uncertainty concept. Example applications are provided for an anti-HCV test where calculations were performed using a commercial spreadsheet. The results show that these models satisfy ISO 15189 principles and that the estimation of clinical sensitivity, clinical specificity, binary results agreement and area under ROC curve area an alternative to the measurement uncertainty concept.

2.	Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard; Sousa, Gracinda. 2015. "The role of uncertainty regarding the results of screening immunoassays in blood establishments ", Transfusion and Apheresis Science  52, 2: 252 - 2. The risk of uncertain results in infectious agents' tests is recognized in blood establishments, being particularly evident during the blood donor selection. The current risk-based approaches require risk assessment and "risk-based thinking". Accordingly, the blood establishment should consider the effect of uncertainty in all the technical decisions taken in a screening laboratory. Since the post-transfusion safety is one of the blood establishments' goals, the risk of post-transfusion infection should be evaluated and actions taken to decrease the chance of blood donations validation use false negative results. This article reviews and discusses the sources of uncertainty of infectious agents' reported results in blood establishments. It describes a set of sources of uncertainty that should be considered in screening immunoassay's decisions. The infectious agents' uncertainty concern is critical for reporting reliable results.

3.	Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard; Sousa, Gracinda. 2015. "Scheme for the selection of measurement uncertainty models in blood establishments' screening immunoassays ", Transfusion and Apheresis Science  52, 1: 42 - 47. Blood establishments routinely perform screening immunoassays to assess safety of the blood components. As with any other screening test, results have an inherent uncertainty. In blood establishments the major concern is the chance of false negatives, due to its possible impact on patients' health. This article briefly reviews GUM and diagnostic accuracy models for screening immunoassays, recommending a scheme to support the screening laboratories' staffs on the selection of a model considering the intended use of the screening results (i.e., post-transfusion safety). The discussion is grounded on a “risk-based thinking¿?, risk being considered from the donor screening interview to the blood components screening immunoassays. A combination of GUM and diagnostic accuracy models to evaluate measurement uncertainty in blood establishments is recommended.

Apresentação oral de trabalho Oral work presentation

1.	Pereira, Paulo. Measurement uncertainty in screening immunoassays in blood establishments,2016 (Outra). Thesis submitted to attain the degree of PhD in Biotechnology with specialization in Microbiology.

Produção científica Scientific production

Produção técnica Technical production

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Produção científica Scientific production

3

Artigos científicos em revistas Papers in periodics

3

Sem arbitragem científica Without scientific refereeing

3

Total

Produção técnica Technical production

1

Outros tipos de produção técnica Other technical production

1

Pedro Miguel Martins Encarnação