Luis Maria de Figureiredo Mascarenhas Lopes da Fonseca. Concluiu Bioquimica pela Universidade de Lisboa em 1998. Actua nas áreas de Ciências Naturais com ênfase em Ciências Biológicas e Ciências Exactas com ênfase em Ciências da Computação e da Informação.
Endereço de acesso a este CV: http://www.degois.pt/visualizador/curriculum.jsp?key=6840113449942472

Nome completo Full name	Luis Maria de Figureiredo Mascarenhas Lopes da Fonseca
Nome em citações bibliográficas Quoting name	Luis L. Fonseca
Categoria profissional Position	Investigador Auxiliar
Domínio científico de atuação Scientific domain	Ciências Exactas-Ciências da Computação e da Informação.

Endereço profissional Professional address

Georgia Institute of Technology The Wallace H. Coulter Department of Biomedical Engineering Laboratory for Biological Systems Analysis 950 Atlantic Drive 3033-2-2000 Atlanta Estados Unidos Telefone: (+1)4043855271 Fax: (+1)4048944243 Correio electrónico: llfonseca@gatech.edu

Sexo Gender

Masculino»Male

2006	Doutoramento Phd
Bioquimica. Universidade Nova de Lisboa, Portugal.

1993-1998	Licenciatura Licentiate degree
Bioquimica (5 anos » years) . Universidade de Lisboa, Portugal.

Georgia Institute of Technology

Mai/2012-Actual

Investigador Auxiliar

Universidade Nova de Lisboa

Out/2009-Abr/2012

Assistente de Investigação

Out/2006-Set/2009

Assistente de Investigação

Jan/2000-Set/2006

Outra Situação

Nov/1998-Dez/1999

Outra Situação

Set/1997-Out/1998

Estagiário Investigador

Participação como Investigador Participation as Researcher

2016-2019 THoR’s HAMMER Technologies for Host Resilience: Host Acute Models of Malaria to study Experimental Resilience

Referência do projeto»Project reference: OD P51OD011132.

2012-2017 MaHPIC - The Malaria Host-Pathogen Interaction Center

Referência do projeto»Project reference: #HHSN272201200031C. Financiador(es)»Funding: The National Institute of Allergy and Infectious Diseases.

2007-2017 BESC - The BioEnergy Science Center is a U.S. Department of Energy

Referência do projeto»Project reference: DE-AC05-00OR22725.

2013-2014 REVERTING THE CARBON CYCLE: FROM CO TO BIODIESEL

Referência do projeto»Project reference: EXPL/BIA-MIC/1455/2012.

2011-2014 PHYTOLAC - Lactococcus Lactis Optimizado para a Produção de Polifenóis Nutracêuticos Derivados de Plantas

Referência do projeto»Project reference: PTDC/EBB-EBI/113727/2009.

2009-2012 Bio-based production of chemical building blocks: Corynebacterium glutamicum as a platform for new and efficient bioprocesses

Referência do projeto»Project reference: ERA-IB/BIO/0002/2008.

2006-2010 Assessment of Pathway Design through Multi-Level Modeling and Experimentation

Referência do projeto»Project reference: MCB-0517135.

2003-2006 Metabolic Trafficking Between Neurons and Astrocytes Under Conditions Implicated in Neurological Disorders: 13C-NMR and Flux Analysis

Referência do projeto»Project reference: POCTI/BIO/39214/2001.

1995-2002 Cultura e Metabolismo de Células Animais: Tráfico Metabólico e Controlo de Produção de Proteínas Recombinantes

Referência do projeto»Project reference: PRAXIS/2/2.1/BIO/1117/95.

Compreende Understandig	Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco).
Fala Speaking	Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco), Japonês (Pouco).
Lê Reading	Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco).
Escreve Writing	Português (Bem), Inglês (Bem), Espanhol (Pouco), Francês (Pouco).

Capítulos de livros publicados Published book chapters

1.	Fonseca, Luís L; Yin, Weiwei; Kemp, Melissa L; Voit, Eberhard O. 2013. Metabolic Systems Modeling, Power-Law Functions.  In Encyclopedia of Systems Biology, ed. Werner DubitzkyOlaf WolkenhauerKwang-Hyun ChoHiroki Yokota, 1272 - 1275. ISBN: 978-1-4419-9862-0. New York, NY: Springer New York.

Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing

1.	Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy; Yang, Zamin K; Tschaplinski, Timothy J; Dixon, Richard A; Voit, Eberhard O. 2018. "Mathematical models of lignin biosynthesis", Biotechnology for Biofuels 11, 1: 34 - 34.

2.	Olivença, Daniel V; Uliyakina, Inna; Fonseca, Luis L; Amaral, Margarida D; Voit, Eberhard O; Pinto, Francisco R. 2018. "A Mathematical Model of the Phosphoinositide Pathway", Scientific Reports 8, 1: 3904 - 0.

3.	M. Downs, D; V. Bazurto, J; Gupta, Anuj; L. Fonseca, L; O. Voit, E. 2018. "The three-legged stool of understanding metabolism: integrating metabolomics with biochemical genetics and computational modeling", AIMS Microbiology 4, 2: 289 - 303.

4.	Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy L; Yang, Zamin K; Tschaplinski, Timothy J; Dixon, Richard A; Voit, Eberhard O. 2018. "A dynamic model of lignin biosynthesis in Brachypodium distachyon", Biotechnology for Biofuels 11, 1: 253 - 253.

5.	Fonseca, Luis L; Joyner, Chester J; Saney, Celia L; Moreno, Alberto; Barnwell, John W; Galinski, Mary R; Voit, Eberhard O. 2018. "Analysis of erythrocyte dynamics in Rhesus macaque monkeys during infection with Plasmodium cynomolgi", Malaria Journal 17, 1: 410 - 0.

6.	MR, Galinski; SA, Lapp; MS, Peterson; F, Ay; CJ, Joyner; KG, LE R; LL, Fonseca; EO, Voit; CONSORTIUM, MAHPIC. 2017. "Plasmodium knowlesi: a superb in vivo nonhuman primate model of antigenic variation in malaria.", Parasitology 0, 0: 1 - 16.

7.	Fonseca, Luis L; Joyner, Chester J; Galinski, Mary R; Voit, Eberhard O. 2017. "A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta", Malaria Journal 16, 1: 375 - 0.

8.	Tang, Yan; Gupta, Anuj; Garimalla, Swetha; Galinski, Mary R; Styczynski, Mark P; Fonseca, Luis L; Voit, Eberhard O. 2017. "Metabolic modeling helps interpret Transcriptomic changes during malaria", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 0: 0 - 0.

9.	Fonseca, Luis L; Alezi, Harnel S; Moreno, Alberto; Barnwell, John W; Galinski, Mary R; Voit, Eberhard O. 2016. "Quantifying the removal of red blood cells in Macaca mulatta during a Plasmodium coatneyi infection", Malaria Journal 15, 1: 410 - 425.

10.	Dam, Phuongan; Fonseca, Luis L; Konstantinidis, Konstantinos T; Voit, Eberhard O. 2016. "Dynamic models of the complex microbial metapopulation of lake mendota", npj Systems Biology and Applications 2, 0: 16007 - 16.

11.	Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Witt, Stephan N. 2016. "Analysis of the Involvement of Different Ceramide Variants in the Response to Hydroxyurea Stress in Baker's Yeast", PLOS ONE 11, 1: e0146839 - e0146839.

12.	Dolatshahi, Sepideh; Fonseca, Luis L; Voit, Eberhard O. 2016. "New insights into the complex regulation of the glycolytic pathway in Lactococcus lactis. I. Construction and diagnosis of a comprehensive dynamic model", Molecular Biosystems 12, 1: 23 - 36.

13.	Dolatshahi, Sepideh; Fonseca, Luis L; Voit, Eberhard O. 2016. "New insights into the complex regulation of the glycolytic pathway in Lactococcus lactis. II. Inference of the precisely timed control system regulating glycolysis", Mol. BioSyst. 12, 1: 37 - 47.

14.	Fonseca, Luis L; Voit, Eberhard O. 2015. "Comparison of mathematical frameworks for modeling erythropoiesis in the context of malaria infection", Mathematical Biosciences 270, 1: 224 - 236.

15.	Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Dixon, Richard A; Voit, Eberhard O. 2015. "Computational inference of the structure and regulation of the lignin pathway in Panicum virgatum", Biotechnology for Biofuels 8, 1: 151 - 0.

16.	Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Stelling, Jorg. 2015. "Dynamics of the Heat Stress Response of Ceramides with Different Fatty-Acyl Chain Lengths in Baker’s Yeast", PLOS Computational Biology 11, 8: e1004373 - e1004373.

17.	Faria, N.T.; Santos, M.V.; Fernandes, P.; Fonseca, L.L.; Fonseca, C.; Ferreira, F.C.. 2014. "Production of glycolipid biosurfactants, mannosylerythritol lipids, from pentoses and d-glucose/d-xylose mixtures by Pseudozyma yeast strains", Process Biochemistry 49, 11: 1790 - 17.

18.	Radoš, D.; Turner, D.L.; Fonseca, L.L.; Carvalho, A.L.; Blombach, B.; Eikmanns, B.J.; Neves, A.R.; Santos, H.. 2014. "Carbon flux analysis by 13C nuclear magnetic resonance to determine the effect of CO2 on anaerobic succinate production by Corynebacterium glutamicum", Applied and Environmental Microbiology 80, 10: 3015 - 30.

19.	Carvalho, Ana L; Turner, David L; Fonseca, Luís L; Solopova, Ana; Catarino, Teresa; Kuipers, Oscar P; Voit, Eberhard O; Neves, Ana R; Santos, Helena; Zilberstein, Dan. 2013. "Metabolic and Transcriptional Analysis of Acid Stress in Lactococcus lactis, with a Focus on the Kinetics of Lactic Acid Pools", PLoS ONE 8, 7: e68470 - e68470.

20.	Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Stelling, Jorg. 2013. "Coordination of Rapid Sphingolipid Responses to Heat Stress in Yeast", PLoS Computational Biology 9, 5: e1003078 - e1.

21.	Fonseca, Carla P; Fonseca, Luís L; Montezinho, Liliana P; Alves, Paula M; Santos, Helena; Castro, M. M. C. A; Geraldes, Carlos F. G. C. 2013. "23Na multiple quantum filtered NMR characterisation of Na+ binding and dynamics in animal cells: a comparative study and effect of Na+/Li+ competition", European Biophysics Journal 42, 7: 503 - 519.

22.	Fonseca, Luis L; Chen, Po-Wei; Voit, Eberhard O. 2012. "Canonical Modeling of the Multi-Scale Regulation of the Heat Stress Response in Yeast", Metabolites 2, 4: 221 - 241.

23.	Fonseca, Luis L; Sánchez, Claudia; Santos, Helena; Voit, Eberhard O. 2011. "Complex coordination of multi-scale cellular responses to environmental stress", Molecular BioSystems 7, 3: 731 - 731.

24.	Fonseca, César; Olofsson, Kim; Ferreira, Carla; Runquist, David; Fonseca, Luís L; Hahn-Hägerdal, Bärbel; Lidén, Gunnar. 2011. "The glucose/xylose facilitator Gxf1 from Candida intermedia expressed in a xylose-fermenting industrial strain of Saccharomyces cerevisiae increases xylose uptake in SSCF of wheat straw", Enzyme and Microbial Technology 48, 6-7: 518 - 525.

25.	Ndukum, Juliet; Fonseca, Luís L; Santos, Helena; Voit, Eberhard O; Datta, Susmita. 2011. "Statistical Inference Methods for Sparse Biological Time Series Data", BMC Systems Biology 5, 1: 57 - 57.

26.	Voit, E.O.; Goel, G.; Chou, I.-C.; Fonseca, L.L.. 2009. "Estimation of metabolic pathway systems from different data sources", IET Systems Biology 3, 6: 513 - 513.

27.	Castro, Rute; Neves, Ana R; Fonseca, Luís L; Pool, Wietske A; Kok, Jan; Kuipers, Oscar P; Santos, Helena. 2009. " Characterization of the individual glucose uptake systems of Lactococcus lactis /: mannose-PTS, cellobiose-PTS and the novel GlcU permease ", Molecular Microbiology 71, 3: 795 - 806.

28.	Cerdán, Sebastián; Sierra, Alejandra; Fonseca, Luis L; Ballesteros, Paloma; Rodrigues, Tiago B. 2009. " The turnover of the H3 deuterons from (2- 13 C) glutamate and (2- 13 C) glutamine reveals subcellular trafficking in the brain of partially deuterated rats ", Journal of Neurochemistry 109, S1: 63 - 72.

29.	Jorge, C.; FONSECA, L. L; Boos, W.; SANTOS, H.. 2008. "Role of periplasmic trehalase in uptake of trehalose by the thermophilic bacterium Rhodothermus marinus", JOURNAL OF BACTERIOLOGY  74, 6: 1871 - 1878.

30.	Ramírez, Belén G; Rodrigues, Tiago B; Violante, Inês R; Cruz, Fátima; Fonseca, Luís L; Ballesteros, Paloma; Castro, M. M. C; García-Martín, María L; Cerdán, Sebastián. 2007. "Kinetic properties of the redox switch/redox coupling mechanism as determined in primary cultures of cortical neurons and astrocytes from rat brain", Journal of Neuroscience Research 85, 15: 3244 - 3253.

31.	Cerdán, Sebastián; Rodrigues, Tiago B; Sierra, Alejandra; Benito, Marina; Fonseca, Luis L; Fonseca, Carla P; García-Martín, María L. 2006. "The redox switch/redox coupling hypothesis", Neurochemistry International 48, 6-7: 523 - 530.

32.	Fonseca, Luís L; Monteiro, Miguel A; Alves, Paula M; Carrondo, Manuel J; Santos, Helena. 2005. "Cultures of rat astrocytes challenged with a steady supply of glutamate: New model to study flux distribution in the glutamate-glutamine cycle", Glia 51, 4: 286 - 296.

33.	Santos, S¿nia S; Fonseca, Lu¿s L; Monteiro, Miguel A; Carrondo, Manuel J; Alves, Paula M. 2005. "Culturing primary brain astrocytes under a fully controlled environment in a novel bioreactor", Journal of Neuroscience Research 79, 1-2: 26 - 32.

34.	Fonseca, Luis L; Alves, Paula M; Carrondo, Manuel J; Santos, Helena. 2001. "Effect of ethanol on the metabolism of primary astrocytes studied by13C- and31P-NMR spectroscopy", Journal of Neuroscience Research 66, 5: 803 - 811.

35.	ALVES, P. M; FONSECA, L. L; PEIXOTO, C. C; ALMEIDA, A. C; CARRONDO, M. J. T; SANTOS, H.. 2000. "NMR Studies on Energy Metabolism of Immobilised Primary Neurons and Astrocytes during Hypoxia, Ischemia and Hypoglycemia", NMR in Biomed. 13, 0: 438 - 448.

Produção científica Scientific production

Total

Produção científica Scientific production

36

Livros e capítulos Books and book chapters

1

Capítulos de livros publicados Published book chapters

1

Artigos científicos em revistas Papers in periodics

35

Com arbitragem científica With scientific refereeing

35

	Carla Sofia Rodrigues Ferreira
	Inês Ribeiro Violante
	Maria Helena Dias dos Santos