Curriculum Vitae

José António de Sousa Moreira

Data da última atualização »Last update : 30/06/2015


José António de Sousa Moreira. Concluiu Química-Física pela Universidade de Santiago de Compostela em 2000. É Professor Auxiliar na Universidade do Algarve. Publicou 25 artigos em revistas especializadas e 21 trabalhos em actas de eventos. Recebeu 1 prémio e/ou homenagem. Entre 2005 e 2009 coordenou 2 projectos de investigação. Actua na área de Ciências Exactas com ênfase em Química. Nas suas actividades profissionais interagiu com 50 colaboradores em co-autorias de trabalhos científicos. No seu curriculum DeGóis os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Nitrosação de base do ADN, Mecanismos de Reação, Química, Relações Estrutura Reatividade e ALKYL NITRITES; DECOMPOSITION; AMIDES.


Endereço de acesso a este CV:

http://www.degois.pt/visualizador/curriculum.jsp?key=1151819664985000


Dados pessoais (Personal data)
Nome completo
Full name
José António de Sousa Moreira
Nome em citações bibliográficas
Quoting name
Moreira, José António
Categoria profissional
Position
Professor Auxiliar
Domínio científico de atuação
Scientific domain
Ciências Exactas-Química.
Endereço profissional
Professional address
Universidade do Algarve
Faculdade de Ciências e Tecnologia
Departamento de Química e Farmácia
Campus de Gambelas
8005-139 Faro
Portugal
Telefone: (+351)289800900Extensão: 7864
Fax: (+351)289800066
Correio electrónico: jmoreira@ualg.pt
Homepage: w3.ualg.pt/~jmoreira
Sexo
Gender
Masculino»Male




Graus Académicos (Academic Degrees)
1995-2000 Doutoramento
Phd
Química-Física.
Universidade de Santiago de Compostela, Espanha.
Instituição portuguesa que atribuiu reconhecimento/equivalência/registo » Portuguese Instituition providing acknowledgement/equivalence/registry : Universidade do Algarve.
Com o tipo » With the type: Registo » Registry.

1992-1995 Mestrado
Master degree
Química Orgânica Tecnológica (2 anos » years) .
Universidade Nova de Lisboa, Portugal.

1985-1991 Licenciatura
Licentiate degree
Química (4 anos » years) .
Universidade de Lisboa, Portugal.





Vínculos profissionais (Professional Positions)
Universidade do Algarve
Jan/2001-Actual Professor Auxiliar





Projetos de Investigação (Research projects)
Participação como Investigador responsável
Participation as responsible Researcher
2007-2009
Correlações Estrutura Reactividade em Reacções de Transferência do Grupo Nitroso para Nucleófilos-Structure-reactivity relationships on nitroso group transfer to nucleophiles
Referência do projeto»Project reference: PPCDT/QUI/57077/2004.
PPCDT
Financiador(es)»Funding: Fundação para a Ciência e a Tecnologia.

2005-2007
Correlações Estrutura Reactividade em Reacções de Transferência do Grupo Nitroso para Nucleófilos- Structure-reactivity relationships on nitroso group transfer to nucleophiles
Referência do projeto»Project reference: POCI/QUI/57077/2004.
POCI
Financiador(es)»Funding: Fundação para a Ciência e a Tecnologia.






Línguas (Languages)
Compreende
Understandig
Português (Bem), Espanhol (Bem), Galego (Bem), Francês (Razoavelmente), Inglês (Bem).
Fala
Speaking
Português (Bem), Espanhol (Bem), Galego (Bem), Francês (Pouco), Inglês (Razoavelmente).

Reading
Português (Bem), Espanhol (Bem), Galego (Bem), Francês (Razoavelmente), Inglês (Bem).
Escreve
Writing
Português (Bem), Espanhol (Bem), Galego (Bem), Francês (Pouco), Inglês (Razoavelmente).




Prémios e títulos (Awards Prizes, and Honours)
2001 Prémio extraordinario de doutoramento, Universidade de Santiago de Compostela.




Membro de Associações Profissionais/Científicas (Professional/Scientific Association membership)
Actual Sociedade Portuguesa de Química, Membro.
Actual American Chemical Society, Membro.




Produção científica, técnica e artística/cultural (Scientific, technical and artistical/cultural production)
Artigos em revistas com arbitragem científica
Papers in periodics with scientific refereeing
1. Pessêgo, Márcia; Moreira, José A; Da Costa, A. M. R; Corrochano, P.; Poblete, F. J; García-Río, Luís. 2013. "Electrostatic Repulsion between Cucurbit[7]urils Can Be Overcome in [3]Pseudorotaxane without Adding Salts", The Journal of Organic Chemistry 78, 8: 3886 - 3894.
2. Pessêgo, Márcia; Da Silva, J. P; Moreira, José A; García-Río, Luis. 2013. "Differences in Cucurbit[7]uril: Surfactant Complexation Promoted by the Cationic Head Group", ChemPlusChem 78, 9: 1058 - 1064.
3. Kiazadeh, Asal; Gomes, Henrique L; Rosa da C. A. M; Moreira, José A; de Leeuw, D. M; Meskers, Stefan C. J. 2012. "Intrinsic and extrinsic resistive switching in a planar diode based on silver oxide nanoparticles", Thin Solid Films 522, N/A: 407 - 411.
4. Pessêgo, Márcia; Moreira, José A; García-Río, Luís. 2012. "Evidence of Higher Complexes Between Cucurbit[7]uril and Cationic Surfactants", Chemistry - A European Journal 18, 25: 7931 - 7940.
5. Kiazadeh, Asal; Gomes, Henrique L; Rosa da C. A. M; Moreira, José A; de Leeuw, D. M; Meskers, Stefan C. J. 2011. "Non-volatile memory device using a polymer modified nanocrystal", Materials Science and Engineering: B 176, 19: 1552 - 1555.
6. Pessêgo, Márcia; Basilio, Nuno; Moreira, José A; García-Río, Luís. 2011. "Cucurbit[7]uril: Surfactant Host-Guest Complexes in Equilibrium with Micellar Aggregates", ChemPhysChem 12, 7: 1342 - 1350.
7. Moreira, José A; Rosa da C. A. M; García-Río, Luís; Pessêgo, Márcia. 2011. " Equilibrium constants and protonation site for N -methylbenzenesulfonamides ", Beilstein Journal of Organic Chemistry, 7: 1732 - 1738.
8. Moreira, José A; Pessêgo, Márcia; Rosa da C. A. M. 2011. "Importance of phenols structure on their activity as antinitrosating agents: A kinetic study", Journal of Pharmacy and Bioallied Sciences 3, 1: 128 - 128.
9. Kiazadeh, Asal; Gomes, Henrique L; Da Costa, A. M. R; Rocha, P.; Chen, Q.; Moreira, José A; de Leeuw, D. M; Meskers, Stefan C. J. 2011. "Planar Non-Volatile Memory based on Metal Nanoparticles", MRS Proceedings 1337, n/a: 151 - 156.
10. Basilio, Nuno; García-Río, Luís; Moreira, José A; Pessêgo, Márcia. 2010. "Supramolecular Catalysis by Cucurbit[7]uril and Cyclodextrins: Similarity and Differences", The Journal of Organic Chemistry 75, 3: 848 - 855.
11. Gago, Sandra; Neves, Patrícia; Monteiro, Bernardo; Pessêgo, Márcia; Lopes, André D; Valente, Anabela A; Almeida Paz, F. A; Pillinger, Martyn; Moreira, José A; Silva, Carlos M; Gonçalves, Isabel S. 2009. "Synthesis and Catalytic Properties in Olefin Epoxidation of Octahedral Dichloridodioxidomolybdenum(VI) Complexes Bearing N,N-Dialkylamide Ligands: Crystal Structure of [Mo2O4(mu(2)-O)Cl-2(dmf)(4)]", European Journal of Inorganic Chemistry 2009, 29-30: 4528 - 4537.
12. Francisco, Vitor; García-Río, Luís; Moreira, José A; Stedman, Geoffrey. 2008. "Kinetic study of an autocatalytic reaction: nitrosation of formamidine disulfide", New Journal of Chemistry 32, 12: 2292 - 2292.
13. Moreira, José A; García-Río, Luís; Ramón Leis, J; Adam, Cláudia. 2006. "Nitroso group transfer from N-nitrososulfonamides to thiolate ions. Intrinsic reactivity", Tetrahedron 62, 37: 8822 - 8829.
Abstract The nitroso group transfer from N-nitrososulfonamides to thiolate ions was studied. Based on the results, the reaction rate is strongly dependent on the nature of the leaving group (alg˜-1.30), but virtually independent of the basicity of the thiol (ßnuc˜0.10). This dependence is ascribed to the presence of a nucleophile desolvation equilibrium (ßd) that is followed by the attack of the thiolate ion on the nitroso group via a concerted mechanism. The equilibrium constants for the loss of a nitroso group from a nitrosothiol and an N-nitrososulfonamide were used to obtain the equilibrium constants for the different reactions involved. By using rate–equilibrium correlations, the parameters , ßd, and were obtained. .

14. Moreira, José A; Leis, Jose R; García-Río, Luís; Serantes, David. 2004. "Nitrosation of Amines in Non-Aqueous Solvents - Difference Between N-N=O and O-N=O Nitroso Donors", European Journal of Organic Chemistry 2004, 3: 614 - 622.
Abstract A kinetic study has been carried out on nitroso group transfer from substituted N-methyl-N-nitroso-benzenesulfonamides to different secondary amines: pyrrolidine, piperidine, N-methylpiperazine, and morpholine in cyclohexane. The observed pseudo-first-order rate constant kobs shows a linear and quadratic dependency on the amine concentration with the existence of a primary kinetic isotope effect. Experiments carried out at different temperatures show Arrhenius-type behavior. Addition of isopropylamine (iPrNH2) to the reaction medium produces an increase in kobs. In the presence of a high iPrNH2 concentrations the influence of secondary amine concentration on kobs shows the disappearance of the quadratic dependency of kobs on the secondary amine. These results would be compatible with an addition-elimination mechanism, similar to that observed for the aminolysis of the alkyl nitrites in apolar solvents. The observed behavior in the presence of 18-crown-6 is very different, however. Addition of crown ether catalyses the reaction of aminolysis of alkyl nitrites insofar as it does not alter the rate of the nitroso group transfer from N-nitrososulfonamides. This behavior has been interpreted in terms of a concerted reaction mechanism through cyclical transition states, with four or six centers, involving one or two molecules of secondary amine. Addition of iPrNH2 to the reaction medium causes the appearance of a third reaction path, which emerges through a mixed transition state formed by a molecule of a secondary amine and a molecule of isopropylamine. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).

15. Moreira, José A; Valente, Anabela A; Pillinger, Martyn; Nunes, Carla D; Gonçalves, Isabel S; Lopes, André D; Romão, Carlos C; Kuhn, Fritz E. 2004. "Dichloro and dimethyl dioxomolybdenum(VI)–diazabutadiene complexes as catalysts for the epoxidation of olefins", New Journal of Chemistry 2004, 28: 308 - 313.
Abstract The dioxomolybdenum(VI) complex [MoO2Cl2{p-tolyl(CH3DAB)}] has been prepared in good yield by reaction of the solvent adduct MoO2Cl2(THF)2 with one equivalent of the bidentate ligand N,N-p-tolyl-2,3-dimethyl-1,4-diazabutadiene. Treatment of the dichloro complex with the Grignard reagent CH3MgCl gives the dimethyl derivative [MoO2(CH3)2{p-tolyl(CH3DAB)}]. The complexes are highly active and selective catalysts for the homogeneous epoxidation of cyclooctene using tert-butyl hydroperoxide (TBHP) as the oxidant. In both cases, the initial activity is ca. 175 mol mol–1Mo h–1 and cyclooctene oxide is obtained quantitatively within 4 h. It was possible to recover the dimethyl complex at the end of the reaction and reuse it in a second run with only a small decrease in activity. The complexes are also active and selective for the epoxidation of other olefins, such as 1-octene, 2-octene, cyclododecene and (R)-( )-limonene, with TBHP. The catalytic production of cyclooctene oxide was investigated in detail, varying either the reaction temperature or the initial concentrations of substrate, oxidant and catalyst precursor. Kinetic studies show that the catalyst precursor–oxygen donor complex formation is first-order in TBHP and in the metal complex [MoO2Cl2{p-tolyl(CH3DAB)}]. A specific rate of 3.2 mol–1 dm3 s–1 was found for catalyst formation at 25°C. Activation parameters for this reaction have also been measured (H=48±3 kJ mol–1, S=–112±10 J mol–1 K–1).

16. Moreira, José A; Leis, Jose R; Norberto, Fátima; García-Río, Luís; Araujo, Eduarda; Ribeiro, Lara. 2003. "Mechanism for Basic Hydrolysis of N-Nitrosoguanidines in Aqueous Solution", The Journal of Organic Chemistry 68, 11: 4330 - 4337.
Abstract A kinetic study was carried out on the hydrolysis of two N-nitrosoguanidines, 1-nitroso-1-methyl-3-tolylsulfonylguanidine (TSGNO) and 1-nitroso-1-methyl-3-benzoylguanidine (BCGNO). We observed an absence of buffer catalysis using H2PO4-/HPO42-, H3BO3/H2BO3-, and HCO3-/CO32- regulators and a complex dependency of the rate constant on the pH. We discovered the existence of three simultaneous reaction paths: spontaneous decomposition of the neutral form of the N-nitrosoguanidine, decomposition of the monoanion, and decomposition through the form of the dianion. The analysis of the kinetic data has allowed us to obtain the acidity constant for the formation of the monoanion of the N-nitrosoguanidine, with values of p = 11.5. The reaction rate for the process through the monoanion, k2, decreases as the acidity increases. The application of the principle of nonperfect synchronization shows that the basicity and reactivity do not correlate when there exists a possibility of stabilization of the negative charge by resonance. This behavior is consistent with the mechanism E1cB whereby the stabler the negative charge, the slower the elimination reaction. When dealing with the case of the elimination through the neutral form we observe that the reaction rate increases together with the capacity of stabilization of the positive charge on the nitrogen atom adjacent to the imino group. For the reaction through the dianion we used a maximum value of k3 = 1010 s-1 to estimate the value of p for the formation of the dianion of the N-nitrosoguanidine, obtaining values of p < 24.

17. Moreira, José A; Norberto, Fátima; Leis, Jose R; García-Río, Luís. 2001. "Nitroso Group Transfer from Substituted N-Methyl-N-nitrosobenzenesulfonamides to Amines. Intrinsic and Apparent Reactivity", The Journal of Organic Chemistry 66, 2: 381 - 390.
Abstract We have studied the nitroso group transfer from substituted N-methyl-N-nitrosobenzenesulfonamides to primary and secondary amines, observing that the rate of the reaction increases as a consequence of the presence of electron withdrawing groups on the aromatic ring of the nitrosating agents. The rate constants determined for the nitroso group transfer, ktr, give good Bronsted-type relationships between log ktr (rate constant for nitroso group transfer) and p and p . The study of the nitrosation processes of secondary amines catalyzed by ONSCN and denitrosation catalyzed by SCN-, in combination with the formation equilibrium of ONSCN, has enabled us to calculate the value of the equilibrium constant for the loss of the NO group from a protonated N-nitrosamine (p ), which can be defined by analogy with p . The value of p for the loss of the NO group from an N-methyl-N-nitrosobenzenesulfonamide was obtained in a similar way. By using values of ¿pKNO = p - p , we were able to calculate the equilibrium constant for the nitroso group transfer and characterize the transition state. On the basis of Bronsted-type correlations, we have obtained values of and 0.55, showing a perfectly balanced transition state. In terms of the Marcus theory, the calculation of the intrinsic barriers for the nitroso group transfer reaction shows that the presence of electron withdrawing groups on the aromatic ring of the N-methyl-N-nitrosobenzenesulfonamides does not cause these barriers to vary.

18. Moreira, José A; Leis, Jose R; García-Río, Luís. 2000. "Reactivity in Water/Oil Microemulsions. Influence of Sodium Bis(2-ethylhexyl)sulfosuccinate/Isooctane/Water Microemulsions on the Solvolysis Mechanism of Substituted Benzoyl Chlorides", Journal of the American Chemical Society 122, 42: 10325 - 10334.
Abstract A study was carried out on the solvolysis of the following substituted benzoyl chlorides in sodium bis(2-ethylhexyl)sulfosuccinate (AOT)/isooctane/water microemulsions: 4-CH3O, 3,4-(CH3O)2, 4-CH3, 4-H, 4-Cl, 3-Cl, 4-CF3, 3-CF3, 3-NO2, and 4-NO2. The benzoyl chlorides are found distributed between the isooctane and the interface, where they react with its hydration water. From the kinetic data we have been able to obtain the true rate constant for the reaction at the interface, ki. Two extreme types of behavior have been observed: for those processes which occur via a predominantly dissociative pathway, ki decreases together with W (W = [H2O]/[AOT]), while for those processes which occur through a predominantly associative pathway, the rate constant at the interface, ki, increases as W decreases. The decrease of ki with W is interpreted as being due to the capacity of interfacial water for solvating the leaving Cl-. For the associative process, the increase in the nucleophilic capacity of the interfacial water as W decreases is the factor responsible for the increase in ki, so that the lesser capacity for solvation of the transition state can be compensated for as the water content of the microemulsion decreases. A comparative analysis of the reactivity of substituted benzoyl chlorides at the interface of the microemulsion shows an increase of the rate of the associative pathway and a decrease of the dissociative counterpart. Hence for W = 50, the change between the two reaction pathways is observed for the benzoyl chlorides with substituents 4-Cl and 3-Cl, while in bulk water this change takes place with more electron-attracting substituents. When the water content of the microemulsion decreases (W = 2), only the benzoyl chlorides 4-CH3O and 3,4-(CH3O)2 will react predominantly through the dissociative pathway.

19. Moreira, José A; Bernasconi, Claude F; Huang, Lisa L; Kittredge, Kevin W. 1999. "Intrinsic Rate Constants for Proton Transfer from a Monoketone to Amine Bases and Electrostatic Effects on the Intrinsic Rate Constants for the Deprotonation of Cationic Ketones by OH- ", Journal of the American Chemical Society 121, 8: 1674 - 1680.
Abstract Despite the central importance of monoketones as carbon acids, no intrinsic barriers or intrinsic rate constants for proton transfer to a standard family of bases such as amines have been reported. This paper presents the results of such determinations for the reaction of 2-acetyl-1-methylpyridinium ion (1) with secondary alicyclic amines. They yield log ko = 0.92 in water and log ko = 1.70 in 50% DMSO-50% water (v/v) at 20 °C. These intrinsic rate constants are lower than for any sterically unhindered carbon acids except for nitroalkanes, reflecting the strong p-acceptor character of the CO group as well as the strong solvation of the oxygen in the enolate ion. Rate constants, , for deprotonation of 1 by OH- have also been determined in water and 50% DMSO-50% water, with somewhat different results than those reported by Tobin and Frey (J. Am. Chem. Soc. 1996, 118, 12253). The value in water shows a small positive deviation from a correlation of such rate constants with the corresponding pKa of 17 simple monoketones and aldehydes reported by Keeffe and Kresge; this deviation as well as the much larger positive deviation for the deprotonation of 1-methyl-3-pyridinioacetophenone (7) and 1-pyridinioacetophenone (8) can be attributed to electrostatic effects resulting from transition-state imbalance.

20. Moreira, José A; García-Río, Luís; Leis, Jose R; Boni, Juan C. 1999. "Nitrosation of Amines in Nonaqueous Solvents. 3. Direct Observation of The Intermidiate in Cyclohexane", The Journal of Organic Chemistry 24, 64: 8887 - 8892.
Abstract The reactions of N-methylaniline (MeAn) with 2,2-dichloroethylnitrite (DCEN) and 2,2,2-trichloroethylnitrite (TCEN) in cyclohexane, and N-methylmethoxyamine (MMA) with TCEN in the same solvent, all gave the expected N-nitrosamines. Spectrophotometric monitoring of the MeAn/DCEN and MMA/TCEN reactions showed accumulation of the reaction intermediate. These are the first nitrosations of amines by alkyl nitrites in which observation of the intermediate has been possible; this is attributed to the low basicity of these amines (a) having effectively eliminated the possibility of the intermediate decomposing by base catalysis and (b) having decreased the rate of spontaneous decomposition of the intermediate more than the rate of its formation. Because of the scant capacity of cyclohexane to stabilize charge, it is assumed that both the formation and decomposition of the intermediate occur via concerted mechanisms with four-center transition states: formation through nucleophilic attack by the amine on the nitroso group accompanied by transfer of the amine proton to this group, decomposition through simultaneous cleavage of the N-O bond, and protonation of the alkoxide leaving group.

21. Moreira, José A; Leis, Jose R; Norberto, Fátima; Iley, Jim; García-Río, Luís. 1998. "Kinetics and mechanism of acid hydrolysis of 1-methyl-1-nitroso-3-p-tolylsulfonylguanidine and 1-methyl-1-nitroso-3-benzoylguanidine", Journal of Chemical Society, Perkin Transactions 2 , 1998: 665 - 658.
Kinetics of acid hydrolysis of 1-methyl-1-nitroso-3-p-tolylsulfonylguanidine 2 and of two 1-methyl-1-nitroso-3-benzoylguanidines (4-unsubstituted and 4-chloro) 5 and 6 have been studied. For the acid hydrolysis of 1-methyl-1-nitroso-3-p-tolylsulfonylguanidine 2, the absence of catalysis by thiocyanate ion, and the value of the kinetic solvent isotope effect indicate that either a rate determining proton transfer followed by fast denitrosation or a concerted pathway is involved in the mechanism. In the case of the acid hydrolysis of 1-methyl-1-nitroso-3-benzoylguanidines 5 and 6 it was observed that the protonated form decomposes via two parallel pathways. One involves a slow nucleophilic attack concerted with an intramolecular proton transfer, and the other a slow concerted denitrosation, where a second proton transfer and NO expulsion are simultaneous. .

22. Moreira, José A; Norberto, Fátima; García-Río, Luís; Leis, Jose R. 1998. "Nitrosation and denitrosation of substituted N-methylbenzenesulfonamides. Evidence of an imbanlaced concerted mechanism", Journal of Chemical Society, Perkin Transactions 2, 1998: 1613 - 1620.
The kinetics of the nitrosation reaction of several substituted sulfonamides and of the denitrosation of the resulting products have been studied. The denitrosation rate is first-order with respect to both the nitroso compound and acid concentration and no effect of added nucleophiles was observed. The denitrosation reaction is general-acid catalysed, with a Brønsted parameter, d, of 0.7, which is independent of the substituents on the aromatic ring. Kinetic solvent isotope effects range from kdH3O /kdD3O = 1.20 ± 0.05 to 2.04 ± 0.06 for denitrosation by L3O and from kdAH/kdAD = 1.5 ± 0.2 to 2.3 ± 0.3 for denitrosation by dichloroacetic acid, which suggest that a rate-determining proton transfer is involved in this reaction. For nitrosation reaction, the absence of catalysis by nucleophilic anions, the observed general-base catalysis (NO = 0.3) and the substituent effects suggest a concerted nitrosation–denitrosation process. The Leffler parameters obtained for N· · ·H bond formation (nuc = 0.7) as well as for N· · ·NO bond breaking (lg = 0.17) are in favour of an imbalance in the transition state (imbalance = 0.53) with the development of a positive charge on the nitrogen adjacent to the nitroso group. .

23. Moreira, José A; Norberto, Fátima; García-Río, Luís; Leis, Jose R. 1998. "Stability and nitrosation efficiency of substituted N-methyl-N-nitrosobezenesulfonamides", Journal of Physical Organic Chemistry 11, 10: 756 - 760.
ABSTRACT A series of substituted N-methyl-N-nitrosobenzenesulfonamides [2,4,6-(CH3)3, 4-CH3O, 4-CH3, 4-Cl and 4-NO2] were synthesized. All of them transfer their nitroso group to N-methylaniline in a quantitative manner, the more reactive being those substituted with electron-withdrawing groups, thus resembling some of the known alkyl nitrites. Studies of their acid denitrosation and base-catalysed hydrolysis demonstrated that the nitrosobenzenesulfonamides are fairly stable in aqueous media between pH 2 and 11. Their relative stability in aqueous media together with their ability to transfer the nitroso group to nucleophiles suggest their use as excellent alternatives to alkyl nitrites in both neutral and basic media.

24. Moreira, José A; Iley, Jim; Norberto, Fátima; Leis, Jose R. 1997. "Nitrosation of N-methyl-4-tolylsulfonylguanidine", JOURNAL OF CHEMICAL RESEARCH-S, 3: 88 - 89.
Abstract: Kinetic studies for the nitrosation of N-methyl-4-tolylsulfonylguanidine identify a mechanism involving rapid nitrosation of the N-methyl nitrogen atom followed by slow, general-base-catalysed proton transfer.

25. Norberto, Fátima; Moreira, José A; Rosa, Eduarda; Iley, Jim; Leis, Jose R; Peña, Maria E. 1993. "Kinetics and mechanism of nitrosation of clonidine: a bridge between nitrosation of amines and ureas", Journal of the Chemical Society, Perkin Transactions 2, 9: 1561 - 1561.

Trabalhos completos/resumidos em eventos com arbitragem científica
Papers in conference proceedings with scientific refereeing
1. Kiazadeh, Asal; Gomes, Henrique L; Rosa da C. A. M; Moreira, José A; de Leeuw, D. M; Meskers, Stefan C. J; Forner, Alesssandra. 2010. "Non-volatile memory device using a polymer modified nanocrystal", Trabalho apresentado em 7th International Conference on Nanosciences and Nanotechnologies (NN10), In Book of Abstracts of the 7th International Conference on Nanosciences and Nanotechnologies (NN10), Ouranoupolis Halkidiki.
2. Kiazadeh, Asal; Gomes, Henrique L; Rosa da C. A. M; Moreira, José A; de Leeuw, D. M; Meskers, Stefan C. J. 2010. "Electronic memory devices based on metal nanoparticles", Trabalho apresentado em 4th International Meeting on Developments in Materials, Processes and Applications of Emerging Technologies (MPA 2010), In Book of Abstracts of the 4th International Meeting on Developments in Materials, Processes and Applications of Emerging Technologies (MPA 2010), Braga.
3. Moreira, José A; García-Río, Luís; Stedman, Geoffrey; Francisco, Vitor. 2008. "The kinetics and mechanism of the reaction of nitrous acid with formamidine disulfide", Trabalho apresentado em XIX IUPAC Conference on Physical Organic Chemistry, In Book of Abstracts of the XIX IUPAC Conference on Physical Organic Chemistry, Santiago de Compostela.
4. Moreira, José A; García-Río, Luís. 2008. "Reactivity in ternary microemulsions of DDAB/Water/Dodecane", Trabalho apresentado em XIX IUPAC Conference on Physical Organic Chemistry, In Book of Abstracts of the XIX IUPAC Conference on Physical Organic Chemistry, Santiago de Compostela.
5. Pessêgo, Márcia; Moreira, José A; Rosa da C. A. M. 2008. "Reactivity towards nitroso group: phenols as oxygen or carbon nucleophile?", Trabalho apresentado em XIX IUPAC Conference on Physical Organic Chemistry, In Book of Abstracts of the XIX IUPAC Conference on Physical Organic Chemistry, Santiago de Compostela.
6. Pessêgo, Márcia; Moreira, José A; Rosa da C. A. M. 2007. "Nitrosative Deamination of Purine and Pyrimidine Bases: Implications in DNA Mutagenesis", Trabalho apresentado em XI European Symposium on Organic Reactivity, In Book of Abstracts of the XI European Symposium on Organic Reactivity, Faro.
7. Moreira, José A; Pessêgo, Márcia; Lopes, André D; Lourenço, João P; Grosso, Carla; Gonçalves, Isabel S. 2007. "A kinetic study of oxygen transfer from an oxygen donor to the complex Dichloro dioxomolybdenum(VI) bisdimethylformamide an effective espoxidation catalyst", Trabalho apresentado em XI European Symposium on Organic Reactivity, In Book of Abstracts of the XI European Symposium on Organic Reactivity, Faro.
8. Nunes, Carla D; Valente, Anabela A; Moreira, José A; Lopes, André D; Pillinger, Martyn; Romão, Carlos C; Kuhn, Fritz E; Gonçalves, Isabel S. 2004. "Dichloro and dimethyl dioxomolybdenum(vi)-diazabutadiene complexes as catalysts for the epoxidation of olefins", Trabalho apresentado em XIX Congresso da Sociedade Portuguesa de Química, In Livro de Actas do XIX Congresso da Sociedade Portuguesa de Química, Coimbra.
9. Moreira, José A; Serantes, David; García-Río, Luís; Leis, Jose R. 2001. "Aminolysis of N-methyl-N-nitrosobenzenesulfonamides in Non -Aqueous Solvents", Trabalho apresentado em VIII European Symposium on Organic Reactivity, In Book of Abstracts of the VIII European Symposium on Organic Reactivity, Cavtat.
10. Moreira, José A; García-Río, Luís; Leis, Jose R; Norberto, Fátima. 1999. "Nitroso Group Transfer From Substituted N-Methyl-N-Nitrosobecenesulfonamides To Amines. Intrinsic And Apparent Reactivity", Trabalho apresentado em VII European Symposium on Organic Reactivity, In Book of Abstracts of the VII European Symposium on Organic Reactivity, Ulm.
11. Moreira, José A; García-Río, Luís; Leis, Jose R; Norberto, Fátima. 1997. "Evidence of Concerted Mechanism of Acidic Denitrosation of Substituted N-Nitroso-N-Methyl-Benzene Sulfonamides", Trabalho apresentado em VI European Symposium on Organic Reactivity, In Book of Abstracts of the VI European Symposium on Organic Reactivity, Louvaine-la-neuve.
12. Moreira, José A; García-Río, Luís; Leis, Jose R; Norberto, Fátima. 1997. "Studies on the Reactivity of N-Nitrosophenylsulfonamides", Trabalho apresentado em Winter School in Organic Reactivity, In Book of abstracts of the Winter School in Organic Reactivity, Bressanone-Brixen.
13. Moreira, José A; Leis, Jose R; García-Río, Luís; Norberto, Fátima. 1996. "Comparative Study on the Reactivity of Substituted N-Nitroso Benzylsulfonamides", Trabalho apresentado em The Royal Society of Chemistry 6th Internacional Meeting in Reaction Mechanisms, In Book of Abstracts of The Royal Society of Chemistry 6th Internacional Meeting in Reaction Mechanisms, Canterbury.
14. Moreira, José A; Norberto, Fátima; Leis, Jose R; Rosa, Eduarda. 1995. "Effect of Different Electron Attracting Groups on the Reactivity of Nitrosoguanidines", Trabalho apresentado em V European Symposium on Organic Reactivity, In Book of abstracts of the V European Symposium on Organic Reactivity, Santiago de Compostela.
15. Moreira, José A; Norberto, Fátima; Leis, Jose R; Araujo, Eduarda. 1995. "Nitrosation of Ambident Amides And Derivatives of Guanidines", Trabalho apresentado em V European Symposium on Organic Reactivity, In Book of Abstracts of the V European Symposium on Organic Reactivity, Santiago de Compostela.
16. Moreira, José A; Norberto, Fátima; Iley, Jim; Rosa, Eduarda; Leis, Jose R. 1994. "Synthesis and Reactivity of Nitrosotoluenosulphonylguanidine", Trabalho apresentado em XXV Reunion Bienal de la Real Sociedad Española de Química, In Book of abstracts of the XXV Reunion Bienal de la Real Sociedad Española de Química, Vitória-Gazteiz.
17. Moreira, José A; Norberto, Fátima; Leis, Jose R. 1994. "Nitrosation of Sulfonylguanidine", Trabalho apresentado em 12th Conference on Physical Organic Chemistry IUPAC, In Book of abstracts of the 12th Conference on Physical Organic Chemistry IUPAC, Padova.
18. Moreira, José A; Norberto, Fátima; Iley, Jim; Rosa, Eduarda; Leis, Jose R. 1992. "Studies on the Nitrosation and Denitrosation of the Drug Clonidine", Trabalho apresentado em XXIV Reunion Bienal de la Real Sociedad Española de Química, In Book of Abstracts of the XXIV Reunion Bienal de la Real Sociedad Española de Química, Málaga.
19. Moreira, José A; Morais, José; Farinha, Ascensão. 1992. "Estudo Comparativo dos Detectores de Ionização de Chama e de Azoto-Fósforo no Doseamento de Diclofenac por Cromatografia Gasosa, em Amostras Biológicas", Trabalho apresentado em Encontro de Jovens Investigadores em Ciências Farmacêuticas, In Livro de Actas do Encontro de Jovens Investigadores em Ciências Farmacêuticas, Porto.
20. Moreira, José A; Norberto, Fátima; Iley, Jim; Pombo, Ana. 1991. "Estudo da Toxicidade de Nitrilos", Trabalho apresentado em II Congresso de Ciências Farmacêuticas, In Livro de Actas do II Congresso de Ciências Farmacêuticas, Lisboa.
21. Moreira, José A; Iley, Jim; Norberto, Fátima; Pombo, Ana. 1991. "Oxidation of Nitriles by a Citochrome P-450 Mono-Oxygenase Model System", Trabalho apresentado em XII Encontro da Sociedade Portuguesa de Química, In Livro de Actas do XII Encontro da Sociedade Portuguesa de Química, Coimbra.

Trabalhos completos/resumidos em eventos sem arbitragem científica
Papers in conference proceedings without scientific refereeing
1. Moreira, José A; García-Río, Luís; Pessêgo, Márcia. 2011. "Influence of the Head Group Surfactant on the Complexation with Cucurbit[7]uril", Trabalho apresentado em 13th European Symposium on Organic Reactivity, In Book of Abstracts of the 13th European Symposium on Organic Reactivity, Tartu.
2. Moreira, José A; García-Río, Luís; Pessêgo, Márcia. 2011. "Simultaneous formation of internal and external complexes between CB7 and cationic surfactants", Trabalho apresentado em 4th Iberian Meeting on Colloids and Interfaces, In Book of Abstracts of the 4th Iberian Meeting on Colloids and Interfaces, Porto.
3. Moreira, José A; García-Río, Luís; Pessêgo, Márcia. 2010. "NMR Characterization of Host:Guest Complexes of Cucurbit[7]uril and Alkyltrimethylammoium Surfactants", Trabalho apresentado em 24th Conference of the European Colloid and Interface Society, In Book of Abstracts of the 24th Conference of the European Colloid and Interface Society, Praga.





Dados Complementares (Additional data)


Participação editorial em revistas
Magazine editorial participation
1. Moreira, José A.. Journal of Physical Organic Chemistry, Função ou tipo de participação: Reviewer, Editora: Wiley.
2. Moreira, José A.. Tenside Surfactants Detergents, Função ou tipo de participação: Reviewer, Editora: Hanser.
3. Moreira, José A.. International Journal of Chemical Kinetics, Função ou tipo de participação: Reviewer, Editora: Wiley.







Indicadores de produção (Production indicators)

Total
Produção científica
Scientific production
49

Artigos científicos em revistas
Papers in periodics
25
Com arbitragem científica
With scientific refereeing
25
Trabalhos em eventos
Papers in conference proceedings
24
Com arbitragem científica
With scientific refereeing
21
Sem arbitragem científica
Without scientific refereeing
3


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