António Gil Pereira de Castro
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Data da última atualização
»Last update
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16/03/2011 |
Dados pessoais (Personal data)
Nome completo
Full name |
António Gil Pereira de Castro |
Nome em citações bibliográficas
Quoting name |
Castro, António Gil Pereira de |
Categoria profissional
Position |
Professor Associado |
Endereço profissional
Professional address |
Universidade do Minho Escola de Ciências da Saúde Instituto de Investigação em Ciências da Vida e da Saúde (ICVS) Campus de Gualtar Gualtar 4710-057 Braga Portugal Telefone: (+351)253604815Extensão: 604815 Correio electrónico: acastro@ecsaude.uminho.pt |
Sexo
Gender |
Masculino»Male |
Graus Académicos
(Academic Degrees)
1990-1994 |
Doutoramento Phd |
Microbiologia
(3 anos » years)
.
Universidade do Porto,
Portugal.
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1982-1987 |
Licenciatura Licentiate degree |
Biologia
(4 anos » years)
.
Universidade do Porto,
Portugal.
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Formação complementar ( studies)
2005-2008 |
Pós-Doutoramento Postdoctorate |
3 anos » years.
DNAX Research Institute,
Estados Unidos.
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1998-2000 |
Pós-Doutoramento Postdoctorate |
2 anos » years.
Fundação Calouste Gulbenkian,
Portugal.
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Vínculos profissionais
(Professional Positions)
Out/2002-Actual |
Professor Associado |
Out/2001-Set/2002 |
Professor Auxiliar |
Cooperativa de Ensino Superior Politécnico e Universitário |
Out/2000-Set/2002 |
Professor Auxiliar |
Prémios e títulos (Awards Prizes, and Honours)
1994 |
Prémio Pfizer de Investigação,
Pfizer.
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2006 |
Prémio Citomed R&D, Melhor Poster,
Citomed R&D.
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2006 |
Prémio de Excelência em Imunologia Mário Arala Chaves,
Sociedade Portuguêsa de Imunologia.
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2010 |
SPI Best Paper Award, 2010,
Sociedade Portuguêsa de Imunologia.
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2010 |
Prémio Pulido Valente Ciência 2010,
Fundação Professor Francisco Pulido Valente e Fundação para a Ciência e Tecnologia.
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Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing |
1. |
Nobrega, Claudia; Roque, Susana; Nunes-Alves, Cláudio; Coelho, Angela; Medeiros, Irene; Castro, António G; Appelberg, Rui; Correia-Neves, Margarida. 2010. "Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen", Journal of Immunology {(Baltimore,} Md.: 1950) 184, 1: 351 - 358.
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2. |
Oliveira, João T; Santos, Tírcia C; Martins, Luís; Picciochi, Ricardo; Marques, Alexandra P; Castro, António G; Neves, Nuno M; Mano, João F; Reis, Rui L. 2010. "Gellan gum injectable hydrogels for cartilage tissue engineering applications: in vitro studies and preliminary in vivo evaluation", Tissue Engineering. Part A 16, 1: 343 - 353.
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3. |
Torrado, Egídio; Fraga, Alexandra G; Logarinho, Elsa; Martins, Teresa G; Carmona, Jenny A; Gama, José B; Carvalho, Maria A; Proença, Fernanda; Castro, Antonio G; Pedrosa, Jorge. 2010. "{IFN-gamma-dependent} activation of macrophages during experimental infections by Mycobacterium ulcerans is impaired by the
toxin mycolactone", Journal of Immunology {(Baltimore,} Md.: 1950) 184, 2: 947 - 955.
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4. |
Teixeira, Luzia; Botelho, Ana S; Mesquita, Sandro D; Correia, Alexandra; Cerca, Filipe; Costa, Renata; Sampaio, Paula; Castro, António G; Vilanova, Manuel. 2010. "Plasmacytoid and conventional dendritic cells are early producers of {IL-12} in Neospora caninum-infected mice", Immunology and Cell Biology 88, 1: 79 - 86.
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5. |
Almeida, A J; Cunha, C; Carmona, J A; Sampaio-Marques, B; Carvalho, A; Malavazi, I; Steensma, H Y; Johnson, D I; Leão, C; Logarinho, E; Goldman, G H; Castro, A G; Ludovico, P; Rodrigues, F. 2009. "Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis", Fungal Genetics and Biology: {FG} \& B 46, 12: 919 - 926.
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6. |
Oliveira, J T; Santos, T C; Martins, L; Silva, M A; Marques, A P; Castro, A G; Neves, N M; Reis, R L. 2009. "Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously
implanted in nude mice", Journal of Tissue Engineering and Regenerative Medicine 3, 7: 493 - 500.
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7. |
Gaspar, M M; Cruz, A; Fraga, A G; Castro, A G; Cruz, M E. M; Pedrosa, J. 2008. "Developments on drug delivery systems for the treatment of mycobacterial infections", Current Topics in Medicinal Chemistry 8, 7: 579 - 591. |
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8. |
Mesquita, Ana R; Correia-Neves, Margarida; Roque, Susana; Castro, António G; Vieira, Paulo; Pedrosa, Jorge; Palha, Joana A; Sousa, Nuno. 2008. "{IL-10} modulates depressive-like behavior", Journal of Psychiatric Research 43, 2: 89 - 97.
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9. |
Lima-Rodrigues, Manuel; Valle-Fernandes, Ana; Lamas, Nuno; Cruz, Andrea; Baltazar, Fátima; Milanezi, Fernanda; Nunes, Rui; Reis, Rui M; Pedrosa, Jorge; Castro, António G; Almeida, Armando. 2008. "A new model of laryngitis: neuropeptide, cyclooxygenase, and cytokine profile", The Laryngoscope 118, 1: 78 - 86.
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10. |
Teixeira, L; Botelho, A S; Batista, A R; Meireles, C S; Ribeiro, A; Domingues, H S; Costa, J M. C. D; Castro, A G; Faustino, A M. R; Vilanova, M. 2007. "Analysis of the immune response to Neospora caninum in a model of intragastric infection in mice", Parasite Immunology 29, 1: 23 - 36.
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11. |
Torrado, Egídio; Fraga, Alexandra G; Castro, António G; Stragier, Pieter; Meyers, Wayne M; Portaels, Françoise; Silva, Manuel T; Pedrosa, Jorge. 2007. "Evidence for an intramacrophage growth phase of Mycobacterium ulcerans", Infection and Immunity 75, 2: 977 - 987.
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12. |
Torrado, Egídio; Adusumilli, Sarojini; Fraga, Alexandra G; Small, Pamela L. C; Castro, António G; Pedrosa, Jorge. 2007. "Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has
implications for the control of infection", Infection and Immunity 75, 8: 3979 - 3988.
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13. |
Santos, T C; Marques, A P; Silva, S S; Oliveira, J M; Mano, J F; Castro, A G; Reis, R L. 2007. "In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes", Journal of Biotechnology 132, 2: 218 - 226.
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14. |
Botelho, A S; Teixeira, L; Correia-da-Costa, J M; Faustino, A M. R; Castro, A G; Vilanova, M. 2007. "Neospora caninum: high susceptibility to the parasite in {C57BL/10ScCr} mice", Experimental Parasitology 115, 1: 68 - 75.
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15. |
Cruz, Andrea; Khader, Shabaana A; Torrado, Egidio; Fraga, Alexandra; Pearl, John E; Pedrosa, Jorge; Cooper, Andrea M; Castro, António G. 2006. "Cutting edge: {IFN-gamma} regulates the induction and expansion of {IL-17-producing} {CD4} T cells during mycobacterial infection", Journal of Immunology {(Baltimore,} Md.: 1950) 177, 3: 1416 - 1420. |
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16. |
Neighbors, Margaret; Hartley, Suzanne B; Xu, Xiuling; Castro, Antonio G; Bouley, Donna M; O'Garra, Anne. 2006. "Breakpoints in immunoregulation required for Th1 cells to induce diabetes", European Journal of Immunology 36, 9: 2315 - 2323.
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17. |
Oliveira, Martinha S; Fraga, Alexandra G; Torrado, Egídio; Castro, António G; Pereira, João P; Filho, Adhemar L; Milanezi, Fernanda; Schmitt, Fernando C; Meyers, Wayne M; Portaels, Françoise; Silva, Manuel T; Pedrosa, Jorge. 2005. "Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice", Infection and Immunity 73, 10: 6299 - 6310.
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18. |
Castro, A G; Neighbors, M; Hurst, S D; Zonin, F; Silva, R A; Murphy, E; Liu, Y J; O'Garra, A. 2000. "Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only
in the presence of lipopolysaccharide", The Journal of Experimental Medicine 192, 10: 1529 - 1534. |
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19. |
Castro, A G; Hauser, T M; Cocks, B G; Abrams, J; Zurawski, S; Churakova, T; Zonin, F; Robinson, D; Tangye, S G; Aversa, G; Nichols, K E; Vries, J E.; Lanier, L L; O'Garra, A. 1999. "Molecular and functional characterization of mouse signaling lymphocytic activation molecule {(SLAM):} differential expression
and responsiveness in Th1 and Th2 cells", Journal of Immunology {(Baltimore,} Md.: 1950) 163, 11: 5860 - 5870. |
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20. |
Castro, A G; Silva, R A; Appelberg, R. 1995. "Endogenously produced {IL-12} is required for the induction of protective T cells during Mycobacterium avium infections in
mice", Journal of Immunology {(Baltimore,} Md.: 1950) 155, 4: 2013 - 2019. |
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21. |
Castro, A G; Silva, R A; Minóprio, P; Appelberg, R. 1995. "In vivo evidence for a {non-T} cell origin of interleukin-5", Scandinavian Journal of Immunology 41, 3: 288 - 292. |
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22. |
Appelberg, R; Castro, A G; Gomes, S; Pedrosa, J; Silva, M T. 1995. "Susceptibility of beige mice to Mycobacterium avium: role of neutrophils", Infection and Immunity 63, 9: 3381 - 3387. |
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23. |
Castro, A G; Minóprio, P; Appelberg, R. 1995. "The relative impact of bacterial virulence and host genetic background on cytokine expression during Mycobacterium avium infection
of mice", Immunology 85, 4: 556 - 561. |
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24. |
Appelberg, R; Sarmento, A; Castro, A G. 1995. "Tumour necrosis factor-alpha {(TNF-alpha)} in the host resistance to mycobacteria of distinct virulence", Clinical and Experimental Immunology 101, 2: 308 - 313. |
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25. |
Pedrosa, J; Flórido, M; Kunze, Z M; Castro, A G; Portaels, F; McFadden, J; Silva, M T; Appelberg, R. 1994. "Characterization of the virulence of Mycobacterium avium complex {(MAC)} isolates in mice", Clinical and Experimental Immunology 98, 2: 210 - 216. |
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26. |
Appelberg, R; Castro, A G; Silva, M T. 1994. "Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis", Immunology 83, 2: 302 - 307. |
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27. |
Appelberg, R; Castro, A G; Pedrosa, J; Silva, R A; Orme, I M; Minóprio, P. 1994. "Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium
avium infection", Infection and Immunity 62, 9: 3962 - 3971. |
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28. |
Appelberg, R; Castro, A G; Pedrosa, J; Minóprio, P. 1994. "Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice", Immunology 82, 3: 361 - 364. |
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29. |
Castro, A G; Esaguy, N; Macedo, P M; Aguas, A P; Silva, M T. 1991. "Live but not heat-killed mycobacteria cause rapid chemotaxis of large numbers of eosinophils in vivo and are ingested by the
attracted granulocytes", Infection and Immunity 59, 9: 3009 - 3014. |
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(Production indicators)
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