Luis Maria de Figureiredo Mascarenhas Lopes da Fonseca
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Data da última atualização
»Last update
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08/11/2018 |
Dados pessoais (Personal data)
Nome completo
Full name |
Luis Maria de Figureiredo Mascarenhas Lopes da Fonseca |
Nome em citações bibliográficas
Quoting name |
Luis L. Fonseca |
Categoria profissional
Position |
Investigador Auxiliar |
Domínio científico de atuação
Scientific domain |
Ciências Exactas-Ciências da Computação e da Informação.
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Endereço profissional
Professional address |
Georgia Institute of Technology The Wallace H. Coulter Department of Biomedical Engineering Laboratory for Biological Systems Analysis 950 Atlantic Drive 3033-2-2000 Atlanta Estados Unidos Telefone: (+1)4043855271 Fax: (+1)4048944243 Correio electrónico: llfonseca@gatech.edu |
Sexo
Gender |
Masculino»Male |
Graus Académicos
(Academic Degrees)
2006 |
Doutoramento Phd |
Bioquimica.
Universidade Nova de Lisboa,
Portugal.
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1993-1998 |
Licenciatura Licentiate degree |
Bioquimica
(5 anos » years)
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Universidade de Lisboa,
Portugal.
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Vínculos profissionais
(Professional Positions)
Georgia Institute of Technology |
Mai/2012-Actual |
Investigador Auxiliar |
Universidade Nova de Lisboa |
Out/2009-Abr/2012 |
Assistente de Investigação |
Out/2006-Set/2009 |
Assistente de Investigação |
Jan/2000-Set/2006 |
Outra Situação |
Nov/1998-Dez/1999 |
Outra Situação |
Set/1997-Out/1998 |
Estagiário Investigador |
Projetos de Investigação (Research projects)
Participação como Investigador Participation as Researcher |
2016-2019 THoR’s HAMMER Technologies for Host Resilience: Host Acute Models of Malaria to study Experimental Resilience |
Referência do projeto»Project reference: OD P51OD011132.
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2012-2017 MaHPIC - The Malaria Host-Pathogen Interaction Center |
Referência do projeto»Project reference: #HHSN272201200031C. Financiador(es)»Funding:
The National Institute of Allergy and Infectious Diseases.
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2007-2017 BESC - The BioEnergy Science Center is a U.S. Department of Energy |
Referência do projeto»Project reference: DE-AC05-00OR22725.
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2013-2014 REVERTING THE CARBON CYCLE: FROM CO TO BIODIESEL |
Referência do projeto»Project reference: EXPL/BIA-MIC/1455/2012.
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2011-2014 PHYTOLAC - Lactococcus Lactis Optimizado para a Produção de Polifenóis Nutracêuticos Derivados de Plantas |
Referência do projeto»Project reference: PTDC/EBB-EBI/113727/2009.
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2009-2012 Bio-based production of chemical building blocks: Corynebacterium glutamicum as a platform for new and efficient bioprocesses |
Referência do projeto»Project reference: ERA-IB/BIO/0002/2008.
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2006-2010 Assessment of Pathway Design through Multi-Level Modeling and Experimentation |
Referência do projeto»Project reference: MCB-0517135.
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2003-2006 Metabolic Trafficking Between Neurons and Astrocytes Under Conditions Implicated in Neurological Disorders: 13C-NMR and Flux
Analysis
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Referência do projeto»Project reference: POCTI/BIO/39214/2001.
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1995-2002 Cultura e Metabolismo de Células Animais: Tráfico Metabólico e Controlo de Produção de Proteínas Recombinantes |
Referência do projeto»Project reference: PRAXIS/2/2.1/BIO/1117/95.
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Línguas (Languages)
Compreende Understandig |
Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco). |
Fala Speaking |
Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco), Japonês (Pouco). |
Lê Reading |
Português (Bem), Inglês (Bem), Espanhol (Razoavelmente), Francês (Pouco). |
Escreve Writing |
Português (Bem), Inglês (Bem), Espanhol (Pouco), Francês (Pouco). |
Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Capítulos de livros publicados Published book chapters |
1. |
Fonseca, Luís L; Yin, Weiwei; Kemp, Melissa L; Voit, Eberhard O. 2013. Metabolic Systems Modeling, Power-Law Functions. In Encyclopedia of Systems Biology, ed. Werner DubitzkyOlaf WolkenhauerKwang-Hyun ChoHiroki Yokota, 1272 - 1275. ISBN: 978-1-4419-9862-0. New York, NY: Springer New York.
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Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing |
1. |
Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy; Yang, Zamin K; Tschaplinski, Timothy J; Dixon, Richard A; Voit, Eberhard O. 2018. "Mathematical models of lignin biosynthesis", Biotechnology for Biofuels 11, 1: 34 - 34.
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2. |
Olivença, Daniel V; Uliyakina, Inna; Fonseca, Luis L; Amaral, Margarida D; Voit, Eberhard O; Pinto, Francisco R. 2018. "A Mathematical Model of the Phosphoinositide Pathway", Scientific Reports 8, 1: 3904 - 0.
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3. |
M. Downs, D; V. Bazurto, J; Gupta, Anuj; L. Fonseca, L; O. Voit, E. 2018. "The three-legged stool of understanding metabolism: integrating metabolomics with biochemical genetics and computational modeling", AIMS Microbiology 4, 2: 289 - 303.
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4. |
Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy L; Yang, Zamin K; Tschaplinski, Timothy J; Dixon, Richard A; Voit, Eberhard O. 2018. "A dynamic model of lignin biosynthesis in Brachypodium distachyon", Biotechnology for Biofuels 11, 1: 253 - 253.
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5. |
Fonseca, Luis L; Joyner, Chester J; Saney, Celia L; Moreno, Alberto; Barnwell, John W; Galinski, Mary R; Voit, Eberhard O. 2018. "Analysis of erythrocyte dynamics in Rhesus macaque monkeys during infection with Plasmodium cynomolgi", Malaria Journal 17, 1: 410 - 0.
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6. |
MR, Galinski; SA, Lapp; MS, Peterson; F, Ay; CJ, Joyner; KG, LE R; LL, Fonseca; EO, Voit; CONSORTIUM, MAHPIC. 2017. "Plasmodium knowlesi: a superb in vivo nonhuman primate model of antigenic variation in malaria.", Parasitology 0, 0: 1 - 16.
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7. |
Fonseca, Luis L; Joyner, Chester J; Galinski, Mary R; Voit, Eberhard O. 2017. "A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta", Malaria Journal 16, 1: 375 - 0.
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8. |
Tang, Yan; Gupta, Anuj; Garimalla, Swetha; Galinski, Mary R; Styczynski, Mark P; Fonseca, Luis L; Voit, Eberhard O. 2017. "Metabolic modeling helps interpret Transcriptomic changes during malaria", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 0: 0 - 0.
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9. |
Fonseca, Luis L; Alezi, Harnel S; Moreno, Alberto; Barnwell, John W; Galinski, Mary R; Voit, Eberhard O. 2016. "Quantifying the removal of red blood cells in Macaca mulatta during a Plasmodium coatneyi infection", Malaria Journal 15, 1: 410 - 425.
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10. |
Dam, Phuongan; Fonseca, Luis L; Konstantinidis, Konstantinos T; Voit, Eberhard O. 2016. "Dynamic models of the complex microbial metapopulation of lake mendota", npj Systems Biology and Applications 2, 0: 16007 - 16.
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11. |
Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Witt, Stephan N. 2016. "Analysis of the Involvement of Different Ceramide Variants in the Response to Hydroxyurea Stress in Baker's Yeast", PLOS ONE 11, 1: e0146839 - e0146839.
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12. |
Dolatshahi, Sepideh; Fonseca, Luis L; Voit, Eberhard O. 2016. "New insights into the complex regulation of the glycolytic pathway in Lactococcus lactis. I. Construction and diagnosis of
a comprehensive dynamic model", Molecular Biosystems 12, 1: 23 - 36. |
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13. |
Dolatshahi, Sepideh; Fonseca, Luis L; Voit, Eberhard O. 2016. "New insights into the complex regulation of the glycolytic pathway in Lactococcus lactis. II. Inference of the precisely timed
control system regulating glycolysis", Mol. BioSyst. 12, 1: 37 - 47.
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14. |
Fonseca, Luis L; Voit, Eberhard O. 2015. "Comparison of mathematical frameworks for modeling erythropoiesis in the context of malaria infection", Mathematical Biosciences 270, 1: 224 - 236.
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15. |
Faraji, Mojdeh; Fonseca, Luis L; Escamilla-Treviño, Luis; Dixon, Richard A; Voit, Eberhard O. 2015. "Computational inference of the structure and regulation of the lignin pathway in Panicum virgatum", Biotechnology for Biofuels 8, 1: 151 - 0.
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16. |
Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Stelling, Jorg. 2015. "Dynamics of the Heat Stress Response of Ceramides with Different Fatty-Acyl Chain Lengths in Baker’s Yeast", PLOS Computational Biology 11, 8: e1004373 - e1004373.
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17. |
Faria, N.T.; Santos, M.V.; Fernandes, P.; Fonseca, L.L.; Fonseca, C.; Ferreira, F.C.. 2014. "Production of glycolipid biosurfactants, mannosylerythritol lipids, from pentoses and d-glucose/d-xylose mixtures by Pseudozyma
yeast strains", Process Biochemistry 49, 11: 1790 - 17. |
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18. |
Radoš, D.; Turner, D.L.; Fonseca, L.L.; Carvalho, A.L.; Blombach, B.; Eikmanns, B.J.; Neves, A.R.; Santos, H.. 2014. "Carbon flux analysis by 13C nuclear magnetic resonance to determine the effect of CO2 on anaerobic succinate production by
Corynebacterium glutamicum", Applied and Environmental Microbiology 80, 10: 3015 - 30. |
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19. |
Carvalho, Ana L; Turner, David L; Fonseca, Luís L; Solopova, Ana; Catarino, Teresa; Kuipers, Oscar P; Voit, Eberhard O; Neves, Ana R; Santos, Helena; Zilberstein, Dan. 2013. "Metabolic and Transcriptional Analysis of Acid Stress in Lactococcus lactis, with a Focus on the Kinetics of Lactic Acid Pools", PLoS ONE 8, 7: e68470 - e68470.
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20. |
Chen, Po-Wei; Fonseca, Luis L; Hannun, Yusuf A; Voit, Eberhard O; Stelling, Jorg. 2013. "Coordination of Rapid Sphingolipid Responses to Heat Stress in Yeast", PLoS Computational Biology 9, 5: e1003078 - e1.
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21. |
Fonseca, Carla P; Fonseca, LuÃs L; Montezinho, Liliana P; Alves, Paula M; Santos, Helena; Castro, M. M. C. A; Geraldes, Carlos F. G. C. 2013. "23Na multiple quantum filtered NMR characterisation of Na+ binding and dynamics in animal cells: a comparative study and effect
of Na+/Li+ competition", European Biophysics Journal 42, 7: 503 - 519.
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22. |
Fonseca, Luis L; Chen, Po-Wei; Voit, Eberhard O. 2012. "Canonical Modeling of the Multi-Scale Regulation of the Heat Stress Response in Yeast", Metabolites 2, 4: 221 - 241.
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23. |
Fonseca, Luis L; Sánchez, Claudia; Santos, Helena; Voit, Eberhard O. 2011. "Complex coordination of multi-scale cellular responses to environmental stress", Molecular BioSystems 7, 3: 731 - 731.
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24. |
Fonseca, César; Olofsson, Kim; Ferreira, Carla; Runquist, David; Fonseca, Luís L; Hahn-Hägerdal, Bärbel; Lidén, Gunnar. 2011. "The glucose/xylose facilitator Gxf1 from Candida intermedia expressed in a xylose-fermenting industrial strain of Saccharomyces
cerevisiae increases xylose uptake in SSCF of wheat straw", Enzyme and Microbial Technology 48, 6-7: 518 - 525.
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25. |
Ndukum, Juliet; Fonseca, LuÃs L; Santos, Helena; Voit, Eberhard O; Datta, Susmita. 2011. "Statistical Inference Methods for Sparse Biological Time Series Data", BMC Systems Biology 5, 1: 57 - 57.
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26. |
Voit, E.O.; Goel, G.; Chou, I.-C.; Fonseca, L.L.. 2009. "Estimation of metabolic pathway systems from different data sources", IET Systems Biology 3, 6: 513 - 513.
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27. |
Castro, Rute; Neves, Ana R; Fonseca, LuÃs L; Pool, Wietske A; Kok, Jan; Kuipers, Oscar P; Santos, Helena. 2009. " Characterization of the individual glucose uptake systems of Lactococcus lactis /: mannose-PTS,
cellobiose-PTS and the novel GlcU permease ", Molecular Microbiology 71, 3: 795 - 806.
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28. |
Cerdán, Sebastián; Sierra, Alejandra; Fonseca, Luis L; Ballesteros, Paloma; Rodrigues, Tiago B. 2009. " The turnover of the H3 deuterons from (2- 13 C) glutamate and (2- 13
C) glutamine reveals subcellular trafficking in the brain of partially deuterated rats ", Journal of Neurochemistry 109, S1: 63 - 72.
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29. |
Jorge, C.; FONSECA, L. L; Boos, W.; SANTOS, H.. 2008. "Role of periplasmic trehalase in uptake of trehalose by the thermophilic bacterium Rhodothermus marinus", JOURNAL OF BACTERIOLOGY 74, 6: 1871 - 1878.
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30. |
Ramírez, Belén G; Rodrigues, Tiago B; Violante, Inês R; Cruz, Fátima; Fonseca, Luís L; Ballesteros, Paloma; Castro, M. M. C; García-Martín, María L; Cerdán, Sebastián. 2007. "Kinetic properties of the redox switch/redox coupling mechanism as determined in primary cultures of cortical neurons and
astrocytes from rat brain", Journal of Neuroscience Research 85, 15: 3244 - 3253.
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31. |
Cerdán, Sebastián; Rodrigues, Tiago B; Sierra, Alejandra; Benito, Marina; Fonseca, Luis L; Fonseca, Carla P; García-Martín, María L. 2006. "The redox switch/redox coupling hypothesis", Neurochemistry International 48, 6-7: 523 - 530.
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32. |
Fonseca, Luís L; Monteiro, Miguel A; Alves, Paula M; Carrondo, Manuel J; Santos, Helena. 2005. "Cultures of rat astrocytes challenged with a steady supply of glutamate: New model to study flux distribution in the glutamate-glutamine
cycle", Glia 51, 4: 286 - 296.
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33. |
Santos, S¿nia S; Fonseca, Lu¿s L; Monteiro, Miguel A; Carrondo, Manuel J; Alves, Paula M. 2005. "Culturing primary brain astrocytes under a fully controlled environment in a novel bioreactor", Journal of Neuroscience Research 79, 1-2: 26 - 32.
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34. |
Fonseca, Luis L; Alves, Paula M; Carrondo, Manuel J; Santos, Helena. 2001. "Effect of ethanol on the metabolism of primary astrocytes studied by13C- and31P-NMR spectroscopy", Journal of Neuroscience Research 66, 5: 803 - 811.
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35. |
ALVES, P. M; FONSECA, L. L; PEIXOTO, C. C; ALMEIDA, A. C; CARRONDO, M. J. T; SANTOS, H.. 2000. "NMR Studies on Energy Metabolism of Immobilised Primary Neurons and Astrocytes during Hypoxia, Ischemia and Hypoglycemia", NMR in Biomed. 13, 0: 438 - 448. |
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Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Produção científica Scientific production |
36 |
Livros e capítulos Books and book chapters |
1 |
Capítulos de livros publicados Published book chapters |
1 |
Artigos científicos em revistas Papers in periodics |
35 |
Com arbitragem científica With scientific refereeing |
35 |
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