Pedro Henrique Couto Oliveira
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Data da última atualização
»Last update
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02/01/2018 |
Dados pessoais (Personal data)
Nome completo
Full name |
Pedro Henrique Couto Oliveira |
Nome em citações bibliográficas
Quoting name |
Oliveira, PH |
Domínio científico de atuação
Scientific domain |
Ciências Médicas-Biotecnologia Médica. Engenharia e Tecnologia-Biotecnologia Industrial. Ciências Naturais-Ciências Biológicas. Ciências Exactas-Ciências da Computação e da Informação.
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Sexo
Gender |
Masculino»Male |
Graus Académicos
(Academic Degrees)
2006-2010 |
Doutoramento Phd |
Biotecnologia
(4 anos » years)
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Universidade Técnica de Lisboa,
Portugal.
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1999-2005 |
Licenciatura Licentiate degree |
Engenharia Biológica
(5 anos » years)
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Universidade Técnica de Lisboa,
Portugal.
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Formação complementar ( studies)
2013 |
Pós-Doutoramento Postdoctorate |
3 anos » years.
Institut Pasteur,
França.
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2010-2012 |
Pós-Doutoramento Postdoctorate |
4 anos » years.
Universidade Técnica de Lisboa,
Portugal.
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2008-2009 |
Outros Others |
Bioengineering. Massachusetts Institute of Technology,
Estados Unidos.
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2005-2005 |
Outros Others |
Bioengineering. University of London,
Reino Unido.
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Vínculos profissionais
(Professional Positions)
Universidade Técnica de Lisboa |
Jan/2010-Dez/2012 |
Outra Situação |
Línguas (Languages)
Compreende Understandig |
Português (Bem), Inglês (Bem), Francês (Razoavelmente), Chinês (Pouco), Espanhol (Razoavelmente). |
Fala Speaking |
Português (Bem), Inglês (Bem), Francês (Razoavelmente), Chinês (Pouco), Espanhol (Razoavelmente). |
Lê Reading |
Português (Bem), Inglês (Bem), Francês (Bem), Chinês (Pouco), Espanhol (Razoavelmente). |
Escreve Writing |
Português (Bem), Inglês (Bem), Francês (Razoavelmente), Chinês (Pouco), Espanhol (Razoavelmente). |
Prémios e títulos (Awards Prizes, and Honours)
2010 |
Top-Cited Article,
Elsevier.
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Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Capítulos de livros publicados Published book chapters |
1. |
Oliveira, PH. 2014. DNA instability in bacterial genomes: causes and consequences. In Genome Analysis: Current Procedures and Applications, ed. Maria Poptsova, 261 - 284. ISBN: 978-1-908230-29-4. UK: Horizon Press.
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2. |
Marcos, João C; Oliveira, PH. 2012. Biofármacos: Desafios e Limitações. In Conversas com Ciência, 63 - 65. ISBN: 978-989-98077-0-9. Braga, Portugal: Escola de Ciências da Universidade do Minho. |
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3. |
Oliveira, PH; Prazeres, Duarte M. F; Monteiro, Gabriel A. 2012. Structural and segregational instability in plasmid biology. In Plasmids: Genetics, Applications and Health, 79 - 100. ISBN: 978-1-62081-370-6. NY: Nova Publishers.
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Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing |
1. |
Oliveira, Pedro H; Touchon, Marie; Cury, Jean; Rocha, Eduardo P. C. 2017. "The chromosomal organization of horizontal gene transfer in bacteria", Nature Communications 8, 1: 1 - 11.
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2. |
Oliveira, Pedro H; Touchon, Marie; Rocha, Eduardo P. C. 2016. "Regulation of genetic flux between bacteria by restriction–modification systems", Proceedings of the National Academy of Sciences, XX: 201603257 - 201603257.
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3. |
Oliveira, Pedro H; Silva, Cláudia L; Cabral, Joaquim M. S. 2014. "Genomic instability in human stem cells: Current status and future challenges", STEM CELLS 32, 11: 2824 - 2832.
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4. |
Gonçalves, Geisa A. L; Oliveira, Pedro H; Gomes, Ana G; Prather, Kristala L. J; Lewis, Leslie A; Prazeres, Duarte M. F; Monteiro, Gabriel A. 2014. "Evidence that the insertion events of IS2 transposition are biased towards abrupt compositional shifts in target DNA and modulated
by a diverse set of culture parameters", Applied Microbiology and Biotechnology 98, 15: 6609 - 6619.
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5. |
Oliveira, P. H; Touchon, M.; Rocha, E. P. C. 2014. "The interplay of restriction-modification systems with mobile genetic elements and their prokaryotic hosts", Nucleic Acids Research 42, 16: 10618 - 10631.
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6. |
Oliveira, Pedro H; Lobato da S. C; Cabral, Joaquim M. S. 2013. "An Appraisal of Human Mitochondrial DNA Instability: New Insights into the Role of Non-Canonical DNA Structures and Sequence
Motifs", PLoS ONE 8, 3: e59907 - e59907.
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7. |
Oliveira, Pedro H; Mairhofer, Juergen. 2013. "Marker-free plasmids for biotechnological applications – implications and perspectives", Trends in Biotechnology 31, 9: 539 - 547.
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8. |
Lewis, Leslie A; Astatke, Mekbib; Umekubo, Peter T; Alvi, Shaheen; Saby, Robert; Afrose, Jehan; Oliveira, Pedro H; Monteiro, Gabriel A; Prazeres, Duarte M. F. 2012. "Protein-DNA Interactions Define the Mechanistic Aspects of Circle formation and Insertion Reactions in IS2 Transposition", Mobile DNA 3, 1: 1 - 1.
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9. |
Oliveira, Pedro H; Boura, Joana S; Abecasis, Manuel M; Gimble, Jeffrey M; da Silva, C. L; Cabral, Joaquim M. 2012. "Impact of hypoxia and long-term cultivation on the genomic stability and mitochondrial performance of ex vivo expanded human
stem/stromal cells", Stem Cell Research 9, 3: 225 - 236.
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10. |
Borlido, L.; Azevedo, A.M.; Sousa, A.G.; Oliveira, P.H.; Roque, A.C.A.; Aires-Barros, M.R.. 2012. "Fishing human monoclonal antibodies from a CHO cell supernatant with boronic acid magnetic particles", Journal of Chromatography B 903, 1: 163 - 170.
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11. |
Oliveira, Pedro H; Prather, Kristala L. J; Prazeres, Duarte M. F; Monteiro, Gabriel A. 2011. "Mutation detection in plasmid-based biopharmaceuticals", Biotechnology Journal 6, 4: 378 - 391.
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12. |
Oliveira, Pedro H; Prather, Kristala J; Prazeres, Duarte M. F; Monteiro, Gabriel A. 2010. "Analysis of DNA repeats in bacterial plasmids reveals the potential for recurrent instability events", Applied Microbiology and Biotechnology 87, 6: 2157 - 2167.
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13. |
Oliveira, Pedro H; Prather, Kristala J; Prazeres, Duarte M; Monteiro, Gabriel A. 2009. "Structural instability of plasmid biopharmaceuticals: challenges and implications", Trends in Biotechnology 27, 9: 503 - 511.
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14. |
Oliveira, Pedro H; Prazeres, Duarte M; Monteiro, Gabriel A. 2009. "Deletion formation mutations in plasmid expression vectors are unfavored by runaway amplification conditions and differentially
selected under kanamycin stress", Journal of Biotechnology 143, 4: 231 - 238.
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15. |
Ribeiro, Sofia C; Oliveira, Pedro H; Prazeres, Duarte M. F; Monteiro, Gabriel A. 2008. "High Frequency Plasmid Recombination Mediated by 28 bp Direct Repeats", Molecular Biotechnology 40, 3: 252 - 260.
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16. |
Oliveira, Pedro H; Lemos, Francisco; Monteiro, Gabriel A; Prazeres, Duarte M. 2008. "Recombination frequency in plasmid DNA containing direct repeats—predictive correlation with repeat and intervening sequence
length", Plasmid 60, 2: 159 - 165.
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17. |
Oliveira, P.H.; Batagov, A.; Ward, J.; Baganz, F.; Krabben, P.. 2006. "Identification of erythrobactin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea", Letters in Applied Microbiology 42, 4: 375 - 380.
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18. |
Aleixo, Ana I; Oliveira, Pedro H; Diogo, Hermínio P; Minas da P. M. E. 2005. "Enthalpies of formation and lattice enthalpies of alkaline metal acetates", Thermochimica Acta 428, 1-2: 131 - 136.
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Trabalhos completos/resumidos em eventos com arbitragem científica Papers in conference proceedings with scientific refereeing |
1. |
Oliveira, Pedro H; Boura, Joana S; Abecasis, Manuel M; da Silva, C. L; Cabral, Joaquim M. S. 2011. "An appraisal of genetic stability in human mesenchymal stem cells", Trabalho apresentado em 2011 1st Portuguese Meeting in Bioengineering ¿ The Challenge of the XXI Century (ENBENG), In 1st Portuguese Biomedical Engineering Meeting, Lisbon, Portugal.
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Apresentação oral de trabalho Oral work presentation |
1. |
Oliveira, PH; Touchon, M.; Rocha, E. P. C. Restriction-modification systems as key players in horizontal gene transfer and genome diversification,7th New England Biolabs (NEB) Meeting,Poland,2015 (Congresso). |
2. |
Oliveira, PH; Touchon, M.; Rocha, E. P. C. Genetic mobility and the distribution of restriction modification systems in prokaryotes,13th European Conference on Computational Biology (ECCB 2014) (Selected for F1000 Posters),Strasbourg,2014 (Poster).
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3. |
Oliveira, PH; Touchon, M.; Rocha, E. P. C. Genetic mobility and the distribution of restriction modification systems in prokaryotes,EMBO Conference on Microbiology after the Genomics Revolution: Genomes 2014,Paris,2014 (Poster). |
4. |
Oliveira, PH; Rocha, E. P. C. A comparative genomics approach provides new insights into the distribution and evolutionary history of restriction modification
systems in bacteria,Annual Meeting of the Society for Molecular Biology and Evolution,Chicago,2013 (Congresso). |
5. |
Lewis, Leslie A; Gonçalves, Geisa A. L; Oliveira, PH; Astatke, Mekbib; Gomes, Ana G; Prather, Kristala L. J; Alvi, Shaheen; Saby, Robert; Afrose, Jehan; Prazeres, Duarte M. F; Monteiro, Gabriel A. Mechanistic definition of IS2 transposition and the basis for its non-random insertional specificity in relevant DNA-based
biopharmaceuticals.,2013 (Congresso). |
6. |
Oliveira, PH; Boura, Joana S; Abecasis, Manuel M; Gimble, Jeffrey M; da Silva, C. L; Cabral, Joaquim M. Effect of hypoxia and long-term culture on the genomic stability and mitochondrial performance of human mesenchymal stem cells
expanded in vitro for clinical applications,15th European Congress on Biotechnology-Biocrossroads,Istanbul,2012 (Poster). |
7. |
Gonçalves, G.A.L.; Oliveira, PH; Lewis, Leslie A; Prazeres, Duarte M. F; Monteiro, Gabriel A. Identification of IS2 transposition in pVAX1-based plasmid, a common vector for DNA vaccine development,15th European Congress on Biotechnology-Biocrossroads,Turkey,2012 (Poster). |
8. |
Gomes, A.G.; Oliveira, PH. Comparative genomic analysis indicates strand compositional asymmetries as regional landmarks in plasmid evolution,15th European Congress on Biotechnology-Biocrossroads,2012 (Poster). |
9. |
Oliveira, PH; da Silva, C. L; Cabral, Joaquim M. S. An appraisal of human mtDNA instability: role of DNA topology and composition,3rd Scientific Meeting of the Institute for Biotechnology and Bioengineering,Lisbon,2012 (Congresso). |
10. |
Oliveira, PH; Gonçalves, G.A.L.; Lewis, Leslie A; Prazeres, Duarte M. F; Monteiro, Gabriel A. Preferential transposition of the mobile element IS2 into AT- and GC-skew polarity switches,15th European Congress on Biotechnology-Biocrossroads,2012 (Poster). |
11. |
Oliveira, PH. Biological Reactors in Health and Biotechnology,2012 (Seminário). |
12. |
Oliveira, PH; da Silva, C. L; Cabral, Joaquim M. S. An appraisal of human mtDNA instability: role of DNA topology and sequence motifs,15th European Congress on Biotechnology-Biocrossroads,Istanbul,2012 (Congresso). |
13. |
Oliveira, PH; Boura, Joana S; Abecasis, Manuel M; Gimble, J.; da Silva, C. L; Cabral, Joaquim M. S. An appraisal of genetic stability during the ex-vivo expansion of human mesenchymal stem cells,11th International Symposium on Mutations in the Genome,Santorini,2011 (Poster). |
14. |
Oliveira, PH; da Silva, C. L; Cabral, Joaquim M. S. Unusual DNA structures and instability motifs correlate with human mitochondrial deletion breakpoints involved in genetic
disorders and cancer,11th International Symposium on Mutations in the Genome,Santorini,2011 (Poster). |
15. |
Oliveira, PH; Boura, Joana S; Abecasis, Manuel M; da Silva, C. L; Cabral, Joaquim M. S. An appraisal of genetic stability in human mesenchymal stem cells,1st Portuguese Meeting in Bioengineering,Lisbon,2011 (Congresso). |
16. |
Oliveira, PH; Boura, Joana S; Abecasis, Manuel M; Gimble, J.; da Silva, C. L; Cabral, Joaquim M. S. Genetic stability during the ex-vivo expansion of human mesenchymal stem cells for clinical applications,6th International Meeting of the Portuguese Society for Stem Cells and Cellular Therapy (SPCE-TC),Cantanhede,2011 (Congresso). |
17. |
Oliveira, PH; da Silva, C. L; Cabral, Joaquim M. S. Bias in human mitochondrial DNA repeat distribution correlates with common deletion/amplification breakpoints involved in
genetic disorders and cancer,5th International Meeting of the Portuguese Society for Stem Cells and Cellular Therapy (SPCE-TC),Guimarães,2010 (Congresso). |
18. |
Oliveira, PH; Lopes, G.; Prather, Kristala J; Prazeres, Duarte M. F; Monteiro, Gabriel A. Structural instability in plasmid biopharmaceuticals for DNA vaccination,2nd Scientific Meeting of the Institute for Biotechnology and Bioengineering,Braga,2010 (Congresso). |
19. |
Lopes, G.; Oliveira, Pedro H; Prather, Kristala L. J; Prazeres, Duarte M. F; Monteiro, Gabriel A. Rational engineering of E. coli strains and vectors for improved manufacturing of plasmid biopharmaceuticals,2nd MIT-Portugal Annual Conference: Creating Value through Systems Thinking,Porto,2010 (Poster). |
20. |
Oliveira, PH; Prazeres, Duarte M. F; Monteiro, Gabriel A. Hotspots for recombination are widespread among plasmid vectors,3rd FEMS congress,Gothenburg,2009 (Poster). |
21. |
Oliveira, PH; Prather, Kristala L. J; Prazeres, Duarte M. F; Monteiro, Gabriel A. Structural instability in plasmid vectors for DNA vaccination,MicroBiotec 2009,Vilamoura,2009 (Congresso). |
22. |
Oliveira, PH; Prather, Kristala J; Prazeres, Duarte M. F; Monteiro, Gabriel A. III International Conference on Environmental, Industrial and Microbial Biotechnology (BioMicroWorld),III International Conference on Environmental, Industrial and Microbial Biotechnology (BioMicroWorld),Lisbon,2009 (Congresso). |
23. |
Monteiro, Gabriel A; Prazeres, Duarte M. F; Azzoni, A.; Ribeiro, Sofia C; Carvalho, J.; Oliveira, Pedro H; Freitas, S.; Magalhães, S.; Lima, J.; Beira, J.. Design and stability of plasmid vectors,Ist Scientific Meeting of the Institute for Biotechnology and Bioengineering (IBB),Faro,2009 (Poster). |
24. |
Oliveira, PH; Prather, Kristala J; Prazeres, Duarte M. F; Monteiro, Gabriel A. Genome-wide analysis of DNA repeats in bacterial plasmids identifies genetically unstable hotspots and candidate regions for
minimization,8th European Symposium on Biochemical Engineering Science (ESBES),Bologna,2009 (Poster). |
25. |
Santos, Ricardo; Marques, Marco P; Oliveira, Pedro H; Carvalho, F.; Carvalho, C.; Monteiro, Gabriel A; Cabral, Joaquim M. S; Frade, R.; Silva, M.; Fernandes, P.. The sunny side of mycobacteria,30th Annual Congress of the European Society of Mycobacteriology,Porto,2009 (Congresso). |
26. |
Monteiro, Gabriel A; Prazeres, Duarte M. F; Fonseca, L.P.; Martins, S.; Oliveira, Pedro H; Azzoni, A.; Lima, J.. Quality control and monitoring of plasmid biopharmaceuticals,Ist Scientific Meeting of the Institute for Biotechnology and Bioengineering (IBB),Faro,2009 (Poster). |
27. |
Oliveira, PH; Prather, Kristala L. J; Prazeres, Duarte M; Monteiro, Gabriel A. Rational engineering of E. coli strains and vectors for improved manufacturing of plasmid biopharmaceuticals,1st MIT-Portugal Annual Conference: Engineering for Better Jobs,Lisbon,2009 (Poster). |
28. |
Oliveira, PH; Prazeres, Duarte M; Monteiro, Gabriel A. Plasmid DNA instability mediated by direct repeats and type-2 insertion sequences,EMBO conference Recombination Mechanisms,Il Ciocco,2008 (Poster). |
29. |
Oliveira, PH; Marques, Marco P; Santos, Ricardo; Claudino, M.; Monteiro, Gabriel A; Cabral, J.M.S.. Searching for a multipurpose Mycobacterium,XIIIrd MicroBiotec,Lisbon,2007 (Poster). |
30. |
Oliveira, PH; Nunes, S.C.; Ribeiro, Sofia C; Prazeres, Duarte M. F; Monteiro, Gabriel A. Kanamycin-induced recombination in E. coli cells harbouring plasmids with direct repeats,32nd FEBS Congress – Molecular Machines,Vienna,2007 (Poster). |
31. |
Oliveira, PH; Prazeres, Duarte M. F; Monteiro, Gabriel A. Plasmid recombination by direct repeats and type 2 insertion sequences,XIIIrd MicroBiotec,Lisbon,2007 (Poster). |
32. |
Oliveira, PH; Ribeiro, Sofia C; Prazeres, Duarte M. F; Monteiro, Gabriel A. Deletions in Escherichia coli plasmids harbouring direct repeats – Environmental factors and the adaptive response,XVth National Congress of Biochemistry,Aveiro,2006 (Poster). |
33. |
Oliveira, PH; Linde, E.; Baganz, F.; Ward, J.; Krabben, P.. From genome to improved antibiotic production by Saccharopolyspora erythraea,ExGen - Exploiting Genomics Grant Holders,Cambridge,2006 (Poster). |
34. |
Ribeiro, Sofia C; Oliveira, PH; Prazeres, Duarte M. F; Monteiro, Gabriel A. Stress-induced mutation in E. coli cells harbouring plasmids with direct repeats – The adaptive response,31st FEBS Congress – Molecules in health and disease,Istanbul,2006 (Congresso). |
35. |
Krabben, P.; Oliveira, Pedro H; Baganz, F.; Ward, J.. Exploring the substrate spectrum of the antibiotic producing bacteria Saccharopolyspora erythraea,12th European Congress on Biotechnology,Copenhagen,2005 (Congresso). |
36. |
Aleixo, Ana I; Oliveira, Pedro H; Diogo, Hermínio P; Minas da P. M. E. Enthalpies of formation of alkaline metal acetates,6th Mediterranean Conference on Calorimetry and Thermal Analysis,Porto,2003 (Poster). |
Dados Complementares (Additional data)
Participação em eventos Event participation |
Participação como Keynote Speaker Participation as Keynote Speaker |
1. |
Genetic mobility and the distribution of restriction modification systems in prokaryotes, 2014 (Encontro). Nome do evento: Department Days of Institut Pasteur; Nome da Instituição: Institut Pasteur. |
2. |
Mechanistic definition of IS2 transposition and the basis for its non-random insertional specificity in relevant DNA-based
biopharmaceuticals, 2013 (Congresso). Nome do evento: 3rd Annual World Congress of Molecular and Cell Biology; Cidade do evento: Suzhou. |
3. |
Da sala de aula ao laboratório – Uma experiência na primeira pessoa, 2011 (Conferência). Nome do evento: Jornadas de Engenharia Química e Biológica (JEQB); Nome da Instituição: Instituto Superior Técnico; Cidade do evento: Lisbon. |
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Biofármacos: Desafios e Limitações, 2011 (Mesa-Redonda). Nome do evento: Tertúlias FNACiência; Cidade do evento: Guimarães / FNAC Guimarães. |
Participação editorial em revistas Magazine editorial participation |
1. |
Oliveira, PH. Cell Death and Differentiation, Função ou tipo de participação: Reviewer. |
2. |
Oliveira, PH. Nucleic Acids Research, Função ou tipo de participação: Reviewer. |
3. |
Oliveira, PH. FEMS Microbiology Letters, Função ou tipo de participação: Reviewer. |
4. |
Oliveira, PH. Biomed Research International, Função ou tipo de participação: Corpo editorial. |
5. |
Oliveira, PH. Pharmaceutica Analytica Acta, Função ou tipo de participação: Reviewer. |
6. |
Oliveira, PH. PLoS ONE, Função ou tipo de participação: Reviewer. |
7. |
Oliveira, PH. Cell and Tissue Research, Função ou tipo de participação: Reviewer. |
8. |
Oliveira, PH. Bioinformatics, Função ou tipo de participação: Reviewer. |
9. |
Oliveira, PH. Scientific Reports, Função ou tipo de participação: Reviewer. |
10. |
Oliveira, PH. Acta Biomaterialia, Função ou tipo de participação: Reviewer. |
11. |
Oliveira, PH. Food Technology and Biotechnology, Função ou tipo de participação: Reviewer. |
12. |
Oliveira, PH. BMC Genomics, Função ou tipo de participação: Reviewer. |
13. |
Oliveira, PH. Biotechnology Research International, desde 2012/02/01, Função ou tipo de participação: Reviewer. |
Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Produção técnica
Technical production |
Dados complementares
data |
Produção científica Scientific production |
22 |
Livros e capítulos Books and book chapters |
3 |
Capítulos de livros publicados Published book chapters |
3 |
Artigos científicos em revistas Papers in periodics |
18 |
Com arbitragem científica With scientific refereeing |
18 |
Trabalhos em eventos Papers in conference proceedings |
1 |
Com arbitragem científica With scientific refereeing |
1 |
Produção técnica Technical production |
36 |
Outros tipos de produção técnica Other technical production |
36 |
Dados complementares (Additional data) |
17 |
Participação em Eventos Event participation |
4 |
Participação editorial em revistas Magazine editorial participation |
13 |
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