Ana Cecilia Afonso Roque
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Data da última atualização
»Last update
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20/11/2013 |
Dados pessoais (Personal data)
Nome completo
Full name |
Ana Cecilia Afonso Roque |
Nome em citações bibliográficas
Quoting name |
Roque, ACA |
Categoria profissional
Position |
Professor Auxiliar |
Domínio científico de atuação
Scientific domain |
Engenharia e Tecnologia-Biotecnologia Industrial. Engenharia e Tecnologia-Nanotecnologia. Ciências Médicas-Biotecnologia Médica. Ciências Exactas-Química.
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Endereço profissional
Professional address |
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia Centro de Química Fina e Biotecnologia Monte da Caparica Caparica 2929-516 Almada Portugal Telefone: (+351)212948385Extensão: 10985 Fax: (+351)212948550 Correio electrónico: cecilia.roque@fct.unl.pt Homepage: http://sites.fct.unl.pt/biomolecular_eng/ |
Sexo
Gender |
Feminino»Female |
Graus Académicos
(Academic Degrees)
2000-2004 |
Doutoramento Phd |
Biotecnologia
(4 anos » years)
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Universidade Técnica de Lisboa,
Portugal.
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1994-1999 |
Licenciatura Licentiate degree |
Engenharia Química - Biotecnologia
(5 anos » years)
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Universidade Técnica de Lisboa,
Portugal.
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Formação complementar ( studies)
2005-2005 |
Pós-Doutoramento Postdoctorate |
4 anos » years.
Universidade Técnica de Lisboa,
Portugal.
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2004-2005 |
Pós-Doutoramento Postdoctorate |
1 anos » years.
University of Cambridge,
Reino Unido.
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2004-2004 |
Pós-Doutoramento Postdoctorate |
Catholic University of America,
Estados Unidos.
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2003 |
Curso de curta duração Short course |
Supervising and small group teaching.
University of Cambridge,
Reino Unido.
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2003 |
Curso de curta duração Short course |
Supervising undergraduates more effectively.
University of Cambridge,
Reino Unido.
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2003 |
Curso de curta duração Short course |
Introduction to Bioinformatics.
University of Cambridge,
Reino Unido.
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2000-2001 |
Curso de curta duração Short course |
Basics of Building a Business.
University of Cambridge,
Reino Unido.
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1999 |
Curso de curta duração Short course |
Introduction to the UNIX system.
University of Cambridge,
Reino Unido.
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1999 |
Curso de curta duração Short course |
Introduction to Molecular Modelling.
University of Cambridge,
Reino Unido.
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Vínculos profissionais
(Professional Positions)
Universidade Nova de Lisboa |
Dez/2005-Actual |
Professor Auxiliar |
Set/2003-Jun/2005 |
Outra Situação |
Atividades de Ensino (Teaching activities)
Universidade Nova de Lisboa |
Disciplinas lecionadas»Taught units:
- Processos de Separação de Produtos Biológicos(Docente)
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Disciplinas lecionadas»Taught units:
- Engenharia Bioquímica I(Docente)
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Disciplinas lecionadas»Taught units:
- Fenómenos de Transferência I(Regente)
- Tecnologia de Enzimas(Regente)
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Disciplinas lecionadas»Taught units:
- Operações Sólido Fluido(Docente)
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Atividades de Conselhos, Comissões e Consultorias (Councils, Comissions and Consultancy activities)
Universidade Nova de Lisboa |
Mai/2011-Actual |
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Coordenadora Mestrado em Biotecnologia |
Set/2006-Abr/2011 |
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Comissão Científica Mestrado em Biotecnologia |
Atividades de Extensão Universitária (Other services rendered through University)
Universidade Nova de Lisboa |
Abr/2007-Actual |
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Atividade de extensão realizada»Extension activity rendered: - Organizer EXPO FCT |
Set/2006-Out/2007 |
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Atividade de extensão realizada»Extension activity rendered: - Organizer FCT Challengers |
Línguas (Languages)
Compreende Understandig |
Português (Bem), Espanhol (Razoavelmente), Francês (Bem), Inglês (Bem). |
Fala Speaking |
Português (Bem), Espanhol (Razoavelmente), Francês (Razoavelmente), Inglês (Bem). |
Lê Reading |
Português (Bem), Espanhol (Razoavelmente), Francês (Bem), Inglês (Bem). |
Escreve Writing |
Português (Bem), Espanhol (Pouco), Francês (Pouco), Inglês (Bem). |
Prémios e títulos (Awards Prizes, and Honours)
1999 |
Diploma e Prémio de Mérito,
Universidade Técnica de Lisboa.
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2001 |
“Allernova” – Winner team of the “1K Business Plan Competition”,
Cambridge University Entrepreneurs Centre.
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2004 |
Visiting Fellowship,
Fundacao Calouste Gulbenkian.
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2004 |
AJ Banks Award,
Society of Chemical Industry.
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2005 |
Young Investigators Award,
Hoffman-La Roche.
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2005 |
Best PhD thesis,
Grupo CUF, SGPS S.A. and Fundação para a Ciência e a Tecnologia.
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2006 |
PROGRAMA GULBENKIAN DE ESTÍMULO À INVESTIGAÇÃO,
Fundacao Calouste Gulbenkian.
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2010 |
Scientific Merit Award UNL-Santander Totta-Edição 2009/2010,
Universidade Nova de Lisboa e Banco Santander Totta.
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2011 |
SHIC´11 "First Honorable Mention",
Hovione.
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Membro de Associações Profissionais/Científicas (Professional/Scientific Association membership)
Out/2008 - Actual |
Sociedade Portuguesa de Biotecnologia, Membro.
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Jul/2004 - Actual |
International Society of Molecular Recognition, Membro.
ISMR council member.
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Produção científica, técnica e artística/cultural
(Scientific, technical and artistical/cultural
production)
Livros publicados/organizados ou edições Published/organized books or Editions |
1. |
Roque, Ana C. A. 2009. Ligand-Macromolecular Interactions in Drug Discovery. ed. 1, ISBN: 978-1-60761-243-8. Totowa, NJ: Humana Press.
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Capítulos de livros publicados Published book chapters |
1. |
Roque, ACA; Pina, A.S.; Hussain, A.. 2009. An historical overview of drug discovery. In Ligand-Macromolecule Interactions in Drug Discovery, 3 - 12. . NY: Humana Press Inc. . |
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2. |
Roque, ACA; Lowe, C. R. 2008. Affinity chromatography: history, perspectives, limitations and prospects. In Affinity Chromatography: Methods and Protocols , 1 - 21. . NY: Humana Press Inc.. |
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3. |
Roque, ACA; Lowe, C. R. 2008. Rationally designed ligands for use in Affinity Chromatography: An artificial Protein L. In Affinity Chromatography: Methods and Protocols , 93 - 109. . NY: Humana Press Inc. . |
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4. |
Roque, ACA; Lowe, C. R; Gupta, G.. 2005. Design, synthesis, and screening of biomimetic ligands for affinity chromatography. In Methods in Molecular Biology, 43 - 62. . NY: Humana Press, Inc.. |
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Artigos em revistas com arbitragem científica Papers in periodics with scientific refereeing |
1. |
Branco, Ricardo J; Dias, Ana M; Roque, Ana C. 2012. "Understanding the molecular recognition between antibody fragments and protein A biomimetic ligand", Journal of Chromatography A 1244, 1: 106 - 115.
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2. |
Sandu, Irina C. A; Roque, Ana C. A; Matteini, Paolo; Schäfer, Stephan; Agati, Giovanni; Correia, Catarina R; Viana, Joana F. F. P. 2012. "Fluorescence recognition of proteinaceous binders in works of art by a novel integrated system of investigation", Microscopy Research and Technique 75, 3: 316 - 324.
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3. |
Batalha, Iris L; Lowe, Christopher R; Roque, Ana C. 2012. "Platforms for enrichment of phosphorylated proteins and peptides in proteomics", Trends in Biotechnology 30, 2: 100 - 110.
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4. |
Santana, Sara D; Pina, Ana S; Roque, Ana C. 2012. "Immobilization of enterokinase on magnetic supports for the cleavage of fusion proteins", Journal of Biotechnology, 161: 378 - 382.
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5. |
Borlido, L.; Azevedo, A.M.; Sousa, A.G.; Oliveira, P.H.; Roque, A.C.A.; Aires-Barros, M.R.. 2012. "Fishing human monoclonal antibodies from a CHO cell supernatant with boronic acid magnetic particles", Journal of Chromatography B 903, -: 163 - 170.
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6. |
Ataíde, Filipe; Azevedo, Cristiana; Clemente, Joao J; Cunha, Antonio E; Freitas, Filomena; Reis, Maria A; Roque, Ana C; Oliveira, Rui. 2012. "Analysis of oxygen transport enhancement by functionalized magnetic nanoparticles (FMP) in bioprocesses", New Biotechnology 29, xx: S75 - S75.
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7. |
Sandu, Irina C. A; Schäfer, Stephan; Magrini, Donata; Bracci, Susanna; Roque, Cecilia A. 2012. "Cross-Section and Staining-Based Techniques for Investigating Organic Materials in Painted and Polychrome Works of Art: A
Review", Microscopy and Microanalysis 18, 04: 860 - 875.
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8. |
Barroso, Telma; Roque, Ana C. A; Aguiar-Ricardo, Ana. 2012. "Bioinspired and Sustainable Chitosan Based Monoliths for Antibody Capture and Release", RSC Advances, xx: xx - xx.
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9. |
Borlido, L.; Azevedo, A.M.; Roque, A.C.A.; Aires-Barros, M.R.. 2011. "Potential of boronic acid functionalized magnetic particles in the adsorption of human antibodies under mammalian cell culture
conditions", Journal of Chromatography A 1218, 43: 7821 - 7827.
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10. |
Dias, A.M.G.C.; Hussain, A.; Marcos, A.S.; Roque, A.C.A.. 2011. "A biotechnological perspective on the application of iron oxide magnetic colloids modified with polysaccharides", Biotechnology Advances 29, 1: 142 - 155.
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11. |
Bicho, Ana; Roque, Ana C. A; Cardoso, Ana S; Domingos, Patrícia; Batalha, Iris L. 2010. "In vitro studies with mammalian cell lines and gum arabic-coated magnetic nanoparticles", Journal of Molecular Recognition 23, 6: 536 - 542.
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12. |
Bicho, A.; Peça, Inês N; Roque, A.C.A.; Cardoso, M. M. 2010. "Anti-CD8 conjugated nanoparticles to target mammalian cells expressing CD8", International Journal of Pharmaceutics 399, 1-2: 80 - 86.
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13. |
Batalha, Iris L; Hussain, Abid; Roque, A. C. A. 2010. "Gum Arabic coated magnetic nanoparticles with affinity ligands specific for antibodies", Journal of Molecular Recognition 23, 5: 462 - 471.
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14. |
Barroso, Telma; Temtem, Márcio; Hussain, Abid; Aguiar-Ricardo, Ana; Roque, Ana C. 2010. "Preparation and characterization of a cellulose affinity membrane for human immunoglobulin G (IgG) purification", Journal of Membrane Science 348, 1-2: 224 - 230.
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15. |
Pina, A. S; Lowe, C. R; Roque, A. C. A. 2010. "Comparison of Fluorescence Labelling Techniques for the Selection of Affinity Ligands from Solid-Phase Combinatorial Libraries", Separation Science and Technology 45, 15: 2187 - 2193.
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16. |
Ferreira, I.M.P.L.V.O.; Pinho, O.; Monteiro, D.; Faria, S.; Cruz, S.; Perreira, A.; Roque, A.C.; Tavares, P.. 2010. "Short communication: Effect of kefir grains on proteolysis of major milk proteins", Journal of Dairy Science 93, 1: 27 - 31.
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17. |
Roque, Ana C; Bicho, A.; Batalha, Iris L; Cardoso, Ana S; Hussain, Abid. 2009. "Biocompatible and bioactive gum Arabic coated iron oxide magnetic nanoparticles", Journal of Biotechnology 144, 4: 313 - 320.
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18. |
Hussain, A.; Pina, A.S.; Roque, A.C.A.. 2009. "Bio-recognition and detection using liquid crystals", Biosensors and Bioelectronics 25, 1: 1 - 8.
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19. |
Roque, A. C. A; Bispo, S.; Pinheiro, A. R. N; Antunes, J. M. A; Gonçalves, D.; Ferreira, H. A. 2009. "Antibody immobilization on magnetic particles", Journal of Molecular Recognition 22, 2: 77 - 82.
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20. |
Pina, A.S.; Roque, A.C.A.. 2009. "Studies on the molecular recognition between bioactive peptides and angiotensin-converting enzyme", Journal of Molecular Recognition 22, 2: 162 - 168.
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21. |
Roque, A.C.A.; Wilson, O.C.. 2008. "Adsorption of gum Arabic on bioceramic nanoparticles", Materials Science and Engineering: C 28, 3: 443 - 447.
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22. |
Roque, Ana C; Silva, Cláudia S; Taipa, M. Â. 2007. "Affinity-based methodologies and ligands for antibody purification: Advances and perspectives", Journal of Chromatography A 1160, 1-2: 44 - 55.
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23. |
Ferreira, Isabel M. P. L. V. O; Eça, Rosário; Pinho, Olívia; Tavares, Pedro; Pereira, Alice; Cecília Roque, A. 2007. "Development and Validation of an HPLC/UV Method for Quantification of Bioactive Peptides in Fermented Milks", Journal of Liquid Chromatography & Related Technologies 30, 14: 2139 - 2147.
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24. |
Stevenson, Adrian C; Araya-Kleinsteuber, Bernardita; Kioupritzi, Eleftheria; Roque, Ana C. A; Lowe, Christopher R. 2006. "Noncontact excitation of quartz crystal resonator chips", Applied Physics Letters 89, 8: 083516 - 083516.
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25. |
Ruiu, L.; Roque, A.C.A.; Taipa, M.A.; Lowe, C.R.. 2006. "De novo design, synthesis and screening of a combinatorial library of complementary ligands directed towards the surface of
cutinase fromFusarium solani pisi", Journal of Molecular Recognition 19, 4: 372 - 378.
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26. |
Araya-Kleinsteuber, Bernardita; Roque, Ana C. A; Kioupritzi, Eleftheria; Stevenson, Adrian C; Lowe, Christopher R. 2006. "Magnetic acoustic resonance immunoassay (MARIA): a multifrequency acoustic approach for the non-labelled detection of biomolecular
interactions", Journal of Molecular Recognition 19, 4: 379 - 385.
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27. |
Stevenson, A. C; Roque, A. C. A; Araya-Kleinsteuber, B.; Kioupritzi, E.; Lowe, C. R. 2006. "Wireless excitation of quartz crystals immersed in an aqueous fluid", The Analyst 131, 4: 474 - 474.
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28. |
Roque, A. C. A; Lowe, Christopher R. 2006. "Advances and applications of de novo designed affinity ligands in proteomics", Biotechnology Advances 24, 1: 17 - 26.
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29. |
Roque, A. C. A; Lowe, Christopher R. 2005. "Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains", Biotechnology and Bioengineering 91, 5: 546 - 555.
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30. |
Roque, A. C. A; Taipa, M. Â; Lowe, Christopher R. 2005. "Synthesis and screening of a rationally designed combinatorial library of affinity ligands mimicking protein L fromPeptostreptococcus
magnus", Journal of Molecular Recognition 18, 3: 213 - 224.
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31. |
Roque, A. C. A; Taipa, M. Â; Lowe, Christopher R. 2005. "An artificial protein L for the purification of immunoglobulins and Fab fragments by affinity chromatography", Journal of Chromatography A 1064, 2: 157 - 167.
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32. |
Roque, A.C.A.; Lowe, C.R.; Taipa, M.A.. 2004. "Antibodies and Genetically Engineered Related Molecules: Production and Purification", Biotechnology Progress 20, 3: 639 - 654.
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33. |
Roque, A. C. A; Taipa, M.Ângela; Lowe, Christopher R. 2004. "A new method for the screening of solid-phase combinatorial libraries for affinity chromatography", Journal of Molecular Recognition 17, 3: 262 - 267.
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Dados Complementares (Additional data)
Dissertação de Mestrado Master degree dissertation |
1. |
Development of a piezoelectric biosensor based on PVDF films, 2011. |
2. |
Magnetic nanoparticles for Biocatalysis and Bioseparation, 2011. |
3. |
Modified gum Arabic as a coating agent for iron oxide magnetic nanoparticles, 2010. |
4. |
Magnetic nanoparticles for selective adsorption of organic compounds, 2010. |
5. |
Iron oxide nanoparticles - cytotoxicity in Caco2 Cells, 2010. |
6. |
Development of a strategy for the affinity purification of lectin Concavalin Brasiliensis with magnetic nanoparticles, 2010. |
7. |
Development of an affinity pair tag-receptor for recombinant protein expression and purification, 2010. |
8. |
Desenvolvimento de Nanopartículas de PLGA-co-PEG para libertação de Docetaxel em células/tecidos alvo, 2008. |
9. |
Nanopartículas Magnéticas em processos de bioseparação por afinidade, 2008. |
10. |
Preparation of Affinity Membranes using Alternative Solvents, 2008. |
11. |
In vitro studies of Gum Arabic-coated Magnetic Nanoparticles with Mammalian Cell Cultures, 2008. |
Trabalho de conclusão de curso de Bacharelato/Licenciatura Bachelor/Licenciate degree conclusion work |
1. |
Modification of magnetic nanoparticles with biomolecules, 2010. |
2. |
Biopolymer films containing liquid crystals, 2010. |
3. |
Immobilization of enzymes on magnetic nanoparticles, 2010. |
4. |
Encapsulation of liquid crystals on nanoparticles, 2010. |
5. |
IFM for the biochemical study of art, 2010. |
6. |
Modification of magnetic nanoparticles for bioseparation purposes, 2009. |
7. |
Coating of magnetic nanoparticles with EPS polymer, 2009. |
8. |
Gum Arabic coated Magnetic Adsorbents for Bioseparations, 2009. |
9. |
Functionalization of magnetic nanoparticles with biopolymers, 2008. |
10. |
Synthesis and Screening of rationally designed combinatorial libraries for proteomics applications, 2008. |
11. |
Covalent Immobilization of Antibodies to Magnetic Microparticles, 2007. |
12. |
Purification of bioactive peptides, 2007. |
13. |
Interaction studies between bioactive peptides and ACE, 2007. |
Iniciação científica Scientific initiation |
1. |
Biochemistry in Art, 2010. |
Orientação de outra natureza Other orientation |
1. |
Liquid Crystal Embedded Polymer Films, 2010. |
Participação no júri de Graus Académicos Academic Degrees jury participation |
1. |
Roque, ACA. De novo design, synthesis and screening of combinatorial libraries of affinity ligands directed towards the surface of cutinase
from Fusarium solani pisi, 2008. |
1. |
Roque, ACA. Desgomagem enzimática de óleo de soja, 2010. |
2. |
Roque, ACA. Eliminação de dioxinas em cinzas volantes com nanopartículas de ferro, 2008. |
Indicadores de produção
(Production indicators)
Produção científica
Scientific production |
Dados complementares
data |
Produção científica Scientific production |
38 |
Livros e capítulos Books and book chapters |
5 |
Livros publicados ou organizados Published or organized books |
1 |
Capítulos de livros publicados Published book chapters |
4 |
Artigos científicos em revistas Papers in periodics |
33 |
Com arbitragem científica With scientific refereeing |
33 |
Dados complementares (Additional data) |
29 |
Orientações Orientations |
26 |
Participação no Júri de Graus Académicos Academic Degrees jury participation |
3 |
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